BG27091A3 - Метод за получаване на цефамови производни - Google Patents

Метод за получаване на цефамови производни

Info

Publication number: BG27091A3
Authority: BG; Bulgaria
Prior art keywords: obtaining; cepham derivatives; cepham; derivatives; obtaining cepham
Prior art date: 1974-09-03

Application number

BG030902A

Other languages

Bulgarian (bg)

English (en)

Inventor

William Gottstein

Murray Kaplan

Alphonse Granatek

Original Assignee

Bristol - Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-09-03

Filing date

1975-09-01

Publication date

1979-08-15

1975-09-01 Application filed by Bristol - Myers Squibb Company filed Critical Bristol - Myers Squibb Company

1979-08-15 Publication of BG27091A3 publication Critical patent/BG27091A3/xx

Links

150000001781 cephams Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BG030902A 1974-09-03 1975-09-01 Метод за получаване на цефамови производни BG27091A3 (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US50299174A	1974-09-03	1974-09-03
US05/590,971 US4297489A (en)	1974-09-03	1975-06-27	7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (1)

Publication Number	Publication Date
BG27091A3 true BG27091A3 (bg)	1979-08-15

Family

ID=27054342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG030902A BG27091A3 (bg)	1974-09-03	1975-09-01	Метод за получаване на цефамови производни

Country Status (21)

Country	Link
US (1)	US4297489A (sv)
JP (1)	JPS6150956B2 (sv)
AR (1)	AR222771A1 (sv)
BG (1)	BG27091A3 (sv)
CA (4)	CA1135255A (sv)
CH (1)	CH636882A5 (sv)
DD (2)	DD130787A5 (sv)
DE (2)	DE2560655C2 (sv)
DK (4)	DK145262C (sv)
ES (2)	ES440707A1 (sv)
FI (1)	FI62841C (sv)
FR (1)	FR2283686A1 (sv)
HU (1)	HU169490B (sv)
IE (1)	IE43123B1 (sv)
IL (1)	IL48020A (sv)
LU (1)	LU73306A1 (sv)
NL (1)	NL161758C (sv)
NO (1)	NO152509C (sv)
OA (1)	OA05096A (sv)
SE (3)	SE431548B (sv)
YU (5)	YU213275A (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4286089A (en) *	1974-12-27	1981-08-25	Smithkline Corporation	7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4101656A (en) *	1976-07-12	1978-07-18	Smithkline Corporation	7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4278670A (en) *	1976-07-12	1981-07-14	Smithkline Corporation	7-Alpha-oxyiminoacylcephalosporins
DE2724092A1 (de) *	1977-05-27	1978-12-07	Smithkline Corp	Cephalosporine, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
FR2387235A1 (fr) *	1978-01-23	1978-11-10	Fujisawa Pharmaceutical Co	Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
US4374994A (en) *	1979-07-05	1983-02-22	Bristol-Myers Company	Process for preparation of 5-mercaptotetrazolyl-1-acetic acid
US4243803A (en) *	1979-07-05	1981-01-06	Bristol-Myers Company	Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
EP0095029B1 (en) *	1979-11-30	1986-11-05	Fujisawa Pharmaceutical Co., Ltd.	5-thio-tetrazol compounds and their preparation
JPS56158791A (en) *	1980-05-10	1981-12-07	Taisho Pharmaceut Co Ltd	Cephalosporin compound
GR75083B (sv) *	1980-09-17	1984-07-13	Lilly Co Eli
JPS57188594A (en) *	1981-05-15	1982-11-19	Eisai Co Ltd	Preparation of 7-(2-amino-2-phenylacetamido)cephem derivative
US4448958A (en) *	1982-10-20	1984-05-15	Bristol-Myers Company	Purification of ceforanide
US4749522A (en) *	1985-10-31	1988-06-07	Angio-Medical Corporation	Supercritical fluid extraction of animal derived materials
DE3641822A1 (de) *	1986-12-06	1988-06-16	Goedecke Ag	Verwendung von dihydrophenylaminosaeurederivaten und diese enthaltende arzneimittel zur immunmodulation und cytostase

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3819623A (en) *	1968-04-12	1974-06-25	Fujisawa Pharmaceutical Co	3,7-disubstituted cephalosporin compounds
DE1953861C2 (de) *	1969-10-25	1982-12-23	Fujisawa Pharmaceutical Co., Ltd., Osaka	7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren
US3814755A (en) *	1972-08-30	1974-06-04	Bristol Myers Co	7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
GB1478055A (en) *	1973-07-27	1977-06-29	Erba Carlo Spa	Cephalosporin compounds
US4074929A (en)	1973-08-29	1978-02-21	Amp Incorporated	Cable card edge connector
US4110338A (en) *	1973-10-31	1978-08-29	Fujisawa Pharmaceutical Co., Ltd.	Product and preparation of 1H-tetrazole-5-thiol derivatives
US4205166A (en) *	1974-02-20	1980-05-27	Fujisawa Pharmaceutical Co., Ltd.	7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
US4092476A (en) *	1974-02-21	1978-05-30	Beecham Group Limited	Phthalidyl esters of 7-[(α amino, 2 substituted acetamido)-3-(heterocyclic-thio methyl)]cephalosporins
US4068074A (en) *	1974-04-05	1978-01-10	Yamanouchi Pharmaceutical Co., Ltd.	Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group
US4160086A (en) *	1974-04-27	1979-07-03	Beecham Group Limited	3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid
JPS612674B2 (sv) *	1974-06-20	1986-01-27	Meiji Seika Co
US4182863A (en) *	1974-09-03	1980-01-08	Bristol-Myers Company	7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4172196A (en) *	1974-09-03	1979-10-23	Bristol-Myers Company	Certain 7-α-substituted-α-hydroxyacetamido-3-(1-carboxymethyltetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acids
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4286089A (en) *	1974-12-27	1981-08-25	Smithkline Corporation	7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4183925A (en) *	1975-03-27	1980-01-15	Pfizer Inc.	7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
JPS525787A (en) *	1975-06-27	1977-01-17	Bristol Myers Co	Antiibacterial agent
US4013648A (en) *	1975-07-23	1977-03-22	Bristol-Myers Company	Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents
US4220644A (en) *	1976-05-03	1980-09-02	Smithkline Corporation	7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
US4118563A (en) *	1977-11-25	1978-10-03	Bristol-Myers Company	Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

1975
- 1975-06-27 US US05/590,971 patent/US4297489A/en not_active Expired - Lifetime
- 1975-08-21 YU YU02132/75A patent/YU213275A/xx unknown
- 1975-08-27 CA CA000234276A patent/CA1135255A/en not_active Expired
- 1975-08-29 DK DK391075A patent/DK145262C/da not_active IP Right Cessation
- 1975-08-29 FI FI752434A patent/FI62841C/fi not_active IP Right Cessation
- 1975-09-01 NO NO752983A patent/NO152509C/no unknown
- 1975-09-01 DE DE2560655A patent/DE2560655C2/de not_active Expired
- 1975-09-01 BG BG030902A patent/BG27091A3/xx unknown
- 1975-09-01 SE SE7509702A patent/SE431548B/sv not_active IP Right Cessation
- 1975-09-01 DE DE2538804A patent/DE2538804C2/de not_active Expired
- 1975-09-01 IL IL48020A patent/IL48020A/xx unknown
- 1975-09-02 OA OA55597A patent/OA05096A/xx unknown
- 1975-09-02 FR FR7526936A patent/FR2283686A1/fr active Granted
- 1975-09-02 HU HUBI521A patent/HU169490B/hu unknown
- 1975-09-02 LU LU73306A patent/LU73306A1/xx unknown
- 1975-09-03 JP JP50106106A patent/JPS6150956B2/ja not_active Expired
- 1975-09-03 ES ES440707A patent/ES440707A1/es not_active Expired
- 1975-09-03 AR AR260237A patent/AR222771A1/es active
- 1975-09-03 DD DD7500196946A patent/DD130787A5/xx unknown
- 1975-09-03 NL NL7510391.A patent/NL161758C/xx active
- 1975-09-03 DD DD188166A patent/DD123471A5/xx unknown
- 1975-09-03 IE IE1916/75A patent/IE43123B1/en unknown
1977
- 1977-04-20 ES ES457998A patent/ES457998A1/es not_active Expired
1979
- 1979-08-31 DK DK367279A patent/DK147483C/da active
- 1979-09-14 SE SE7907672A patent/SE435279B/sv not_active IP Right Cessation
1980
- 1980-12-02 CH CH890980A patent/CH636882A5/de not_active IP Right Cessation
1981
- 1981-03-12 CA CA372,810A patent/CA1123840A/en not_active Expired
- 1981-03-12 CA CA000372811A patent/CA1135254A/en not_active Expired
- 1981-08-24 CA CA000384513A patent/CA1135256A/en not_active Expired
- 1981-09-16 YU YU2233/81A patent/YU44833B/xx unknown
- 1981-09-16 YU YU02230/81A patent/YU223081A/xx unknown
- 1981-09-16 YU YU2231/81A patent/YU44964B/xx unknown
- 1981-09-16 YU YU2232/81A patent/YU44669B/xx unknown
1982
- 1982-05-27 DK DK240582A patent/DK148796C/da not_active IP Right Cessation
1983
- 1983-09-16 DK DK423383A patent/DK162388C/da active
- 1983-10-07 SE SE8305539A patent/SE453507B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK240582A (da)	1982-05-27
SE435279B (sv)	1984-09-17
IL48020A0 (en)	1975-11-25
YU223281A (en)	1983-12-31
LU73306A1 (sv)	1976-08-13
FI752434A (sv)	1976-03-04
NL7510391A (nl)	1976-03-05
YU213275A (en)	1982-02-28
CA1135255A (en)	1982-11-09
CH636882A5 (de)	1983-06-30
DK162388B (da)	1991-10-21
FR2283686B1 (sv)	1983-07-08
SE431548B (sv)	1984-02-13
SE7907672L (sv)	1979-09-14
IL48020A (en)	1982-02-28
SE8305539D0 (sv)	1983-10-07
HU169490B (sv)	1976-12-28
DK423383A (da)	1983-09-16
DE2538804A1 (de)	1976-07-15
CA1123840A (en)	1982-05-18
SE7509702L (sv)	1976-03-04
SE453507B (sv)	1988-02-08
DK147483C (da)	1985-03-25
DK148796B (da)	1985-09-30
US4297489A (en)	1981-10-27
DE2560655C2 (sv)	1988-07-14
DE2538804C2 (de)	1986-10-16
DK367279A (da)	1979-08-31
JPS6150956B2 (sv)	1986-11-06
AR222771A1 (es)	1981-06-30
NO152509C (no)	1985-10-09
IE43123L (en)	1976-03-03
FR2283686A1 (fr)	1976-04-02
NL161758C (nl)	1980-03-17
YU223081A (en)	1983-12-31
IE43123B1 (en)	1980-12-31
CA1135256A (en)	1982-11-09
CA1135254A (en)	1982-11-09
DD130787A5 (de)	1978-05-03
DK391075A (da)	1976-03-04
ES457998A1 (es)	1978-03-01
NO152509B (no)	1985-07-01
ES440707A1 (es)	1977-07-01
FI62841C (fi)	1983-03-10
JPS5154580A (sv)	1976-05-13
YU44833B (en)	1991-04-30
DK145262C (da)	1983-03-14
DD123471A5 (sv)	1976-12-20
YU44669B (en)	1990-12-31
FI62841B (fi)	1982-11-30
NO752983L (sv)	1976-03-04
DK147483B (da)	1984-08-27
DK145262B (da)	1982-10-18
DK148796C (da)	1986-03-17
SE8305539L (sv)	1983-10-07
YU223181A (en)	1983-12-31
DK162388C (da)	1992-03-16
YU44964B (en)	1991-06-30
YU223381A (en)	1983-06-30
OA05096A (fr)	1981-01-31
DK423383D0 (da)	1983-09-16

Publication	Publication Date	Title
BG26389A3 (bg)	1979-03-15	Метод за получаване на заместени пурини
BG23216A3 (bg)	1977-07-12	Метод за получаване на бензимидазоли
BG26192A3 (bg)	1979-02-15	Метод за получаване на 3-арилокси-3-фенилпропиламини
BG26516A3 (bg)	1979-04-12	Метод за получаване на n-фосфонометил-глицин
BG27086A3 (bg)	1979-08-15	Метод за получаване на хиназолинови производни
SE7512075L (sv)	1976-05-03	Kontinuerlig uppkolningsmetod
BG26518A3 (bg)	1979-04-12	Метод за получаване на производни на фенил-алкан
BG26201A3 (bg)	1979-02-15	Метод за получаване на 7-бета-амино-3-цефем-3-ол- 4-карбонови киселини
BG21208A3 (bg)	1976-03-20	Метод за получаване на 1- алилокси-2- хидрокси -3- алкинилами- нопропани
BG27091A3 (bg)	1979-08-15	Метод за получаване на цефамови производни
BG26374A3 (bg)	1979-03-15	Метод за получаване на бензимидазолови производни
BG26400A3 (bg)	1979-03-15	Метод за получаване на производни на диаминоциклитоли
BG23541A3 (bg)	1977-09-15	Метод за получаване на пиридобензодиазепинони
BG24539A3 (bg)	1978-03-10	Метод за получаване на 1-етил- за- субституирани - фенил - декахидроизохинолини
BG27230A3 (bg)	1979-09-14	Метод за получаване на субституирани индоленини
BG21851A3 (bg)	1976-09-20	Метод за получаване на производни на 1-фенокси -3- амино-пропан-2-ол
BG21233A3 (bg)	1976-03-20	Метод за получаване на цефалоспоринови производни
BG22820A3 (bg)	1977-04-20	Метод за получаване на пиразолони-5
BG26529A3 (bg)	1979-04-12	Метод за получаване на бензодиазепинови производни
BG27227A3 (bg)	1979-09-14	Метод за получаване на 11-дозокси-15-заместени омега- пентанорпростагландини
BG27089A3 (bg)	1979-08-15	Метод за получаване на индохинолизидинови производни
BG27076A3 (bg)	1979-08-15	Метод за получаване на ацетилоктеннитрилно производно
BG26381A3 (bg)	1979-03-15	Метод за получаване на заместени фенилпиперазини
BG26393A3 (bg)	1979-03-15	Метод за получаване на деацетоксицефалоспорини
BG21849A3 (bg)	1976-09-20	Метод за получаване на заместени нитробензофенонови производни