DD130787A5 - Verfahren zur herstellung neuer zwischenprodukte fuer neue cephalosporinderivate - Google Patents

Verfahren zur herstellung neuer zwischenprodukte fuer neue cephalosporinderivate

Info

Publication number: DD130787A5
Authority: DD; German Democratic Republic
Prior art keywords: new; intermediate products; preparing; cephalosporine derivatives; derivatives
Prior art date: 1974-09-03

Application number

DD7500196946A

Other languages

German (de)

English (en)

Inventor

Murray A Kaplan

William J Gottstein

Alphonse P Granatek

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-09-03

Filing date

1975-09-03

Publication date

1978-05-03

1975-09-03 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1978-05-03 Publication of DD130787A5 publication Critical patent/DD130787A5/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DD7500196946A 1974-09-03 1975-09-03 Verfahren zur herstellung neuer zwischenprodukte fuer neue cephalosporinderivate DD130787A5 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US50299174A	1974-09-03	1974-09-03
US05/590,971 US4297489A (en)	1974-09-03	1975-06-27	7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (1)

Publication Number	Publication Date
DD130787A5 true DD130787A5 (de)	1978-05-03

Family

ID=27054342

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DD7500196946A DD130787A5 (de)	1974-09-03	1975-09-03	Verfahren zur herstellung neuer zwischenprodukte fuer neue cephalosporinderivate
DD188166A DD123471A5 (xx)	1974-09-03	1975-09-03

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DD188166A DD123471A5 (xx)	1974-09-03	1975-09-03

Country Status (21)

Country	Link
US (1)	US4297489A (xx)
JP (1)	JPS6150956B2 (xx)
AR (1)	AR222771A1 (xx)
BG (1)	BG27091A3 (xx)
CA (4)	CA1135255A (xx)
CH (1)	CH636882A5 (xx)
DD (2)	DD130787A5 (xx)
DE (2)	DE2538804C2 (xx)
DK (4)	DK145262C (xx)
ES (2)	ES440707A1 (xx)
FI (1)	FI62841C (xx)
FR (1)	FR2283686A1 (xx)
HU (1)	HU169490B (xx)
IE (1)	IE43123B1 (xx)
IL (1)	IL48020A (xx)
LU (1)	LU73306A1 (xx)
NL (1)	NL161758C (xx)
NO (1)	NO152509C (xx)
OA (1)	OA05096A (xx)
SE (3)	SE431548B (xx)
YU (5)	YU213275A (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4286089A (en) *	1974-12-27	1981-08-25	Smithkline Corporation	7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4278670A (en) *	1976-07-12	1981-07-14	Smithkline Corporation	7-Alpha-oxyiminoacylcephalosporins
US4101656A (en) *	1976-07-12	1978-07-18	Smithkline Corporation	7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
DE2724092A1 (de) *	1977-05-27	1978-12-07	Smithkline Corp	Cephalosporine, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
FR2387235A1 (fr) *	1978-01-23	1978-11-10	Fujisawa Pharmaceutical Co	Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
US4374994A (en) *	1979-07-05	1983-02-22	Bristol-Myers Company	Process for preparation of 5-mercaptotetrazolyl-1-acetic acid
US4243803A (en) *	1979-07-05	1981-01-06	Bristol-Myers Company	Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
DE3070258D1 (en) *	1979-11-30	1985-04-11	Fujisawa Pharmaceutical Co	Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
JPS56158791A (en) *	1980-05-10	1981-12-07	Taisho Pharmaceut Co Ltd	Cephalosporin compound
IL63767A0 (en) *	1980-09-17	1981-12-31	Lilly Co Eli	Cephalosporin compounds
JPS57188594A (en) *	1981-05-15	1982-11-19	Eisai Co Ltd	Preparation of 7-(2-amino-2-phenylacetamido)cephem derivative
US4448958A (en) *	1982-10-20	1984-05-15	Bristol-Myers Company	Purification of ceforanide
US4749522A (en) *	1985-10-31	1988-06-07	Angio-Medical Corporation	Supercritical fluid extraction of animal derived materials
DE3641822A1 (de) *	1986-12-06	1988-06-16	Goedecke Ag	Verwendung von dihydrophenylaminosaeurederivaten und diese enthaltende arzneimittel zur immunmodulation und cytostase

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3819623A (en) *	1968-04-12	1974-06-25	Fujisawa Pharmaceutical Co	3,7-disubstituted cephalosporin compounds
DE1953861C2 (de) *	1969-10-25	1982-12-23	Fujisawa Pharmaceutical Co., Ltd., Osaka	7-Tetrazolylacetamido-3-thiomethyl-3-cephem-4- carbonsäuren
US3814755A (en) *	1972-08-30	1974-06-04	Bristol Myers Co	7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
GB1478055A (en) *	1973-07-27	1977-06-29	Erba Carlo Spa	Cephalosporin compounds
US4074929A (en)	1973-08-29	1978-02-21	Amp Incorporated	Cable card edge connector
NL7414119A (nl) *	1973-10-31	1975-05-02	Fujisawa Pharmaceutical Co	Werkwijze ter bereiding van 1h-tetrazool-5-thiol- derivaten en 1-gesubstitueerde 1h-tetrazool- -5-thiolen.
US4205166A (en) *	1974-02-20	1980-05-27	Fujisawa Pharmaceutical Co., Ltd.	7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
US4092476A (en) *	1974-02-21	1978-05-30	Beecham Group Limited	Phthalidyl esters of 7-[(α amino, 2 substituted acetamido)-3-(heterocyclic-thio methyl)]cephalosporins
US4068074A (en) *	1974-04-05	1978-01-10	Yamanouchi Pharmaceutical Co., Ltd.	Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group
US4160086A (en) *	1974-04-27	1979-07-03	Beecham Group Limited	3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid
JPS612674B2 (xx) *	1974-06-20	1986-01-27	Meiji Seika Co
US4182863A (en) *	1974-09-03	1980-01-08	Bristol-Myers Company	7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4172196A (en) *	1974-09-03	1979-10-23	Bristol-Myers Company	Certain 7-α-substituted-α-hydroxyacetamido-3-(1-carboxymethyltetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acids
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4286089A (en) *	1974-12-27	1981-08-25	Smithkline Corporation	7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US4183925A (en) *	1975-03-27	1980-01-15	Pfizer Inc.	7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
JPS525787A (en) *	1975-06-27	1977-01-17	Bristol Myers Co	Antiibacterial agent
US4013648A (en) *	1975-07-23	1977-03-22	Bristol-Myers Company	Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents
US4220644A (en) *	1976-05-03	1980-09-02	Smithkline Corporation	7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
US4118563A (en) *	1977-11-25	1978-10-03	Bristol-Myers Company	Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

1975
- 1975-06-27 US US05/590,971 patent/US4297489A/en not_active Expired - Lifetime
- 1975-08-21 YU YU02132/75A patent/YU213275A/xx unknown
- 1975-08-27 CA CA000234276A patent/CA1135255A/en not_active Expired
- 1975-08-29 FI FI752434A patent/FI62841C/fi not_active IP Right Cessation
- 1975-08-29 DK DK391075A patent/DK145262C/da not_active IP Right Cessation
- 1975-09-01 BG BG030902A patent/BG27091A3/xx unknown
- 1975-09-01 IL IL48020A patent/IL48020A/xx unknown
- 1975-09-01 DE DE2538804A patent/DE2538804C2/de not_active Expired
- 1975-09-01 SE SE7509702A patent/SE431548B/xx not_active IP Right Cessation
- 1975-09-01 NO NO752983A patent/NO152509C/no unknown
- 1975-09-01 DE DE2560655A patent/DE2560655C2/de not_active Expired
- 1975-09-02 FR FR7526936A patent/FR2283686A1/fr active Granted
- 1975-09-02 HU HUBI521A patent/HU169490B/hu unknown
- 1975-09-02 LU LU73306A patent/LU73306A1/xx unknown
- 1975-09-02 OA OA55597A patent/OA05096A/xx unknown
- 1975-09-03 DD DD7500196946A patent/DD130787A5/xx unknown
- 1975-09-03 IE IE1916/75A patent/IE43123B1/en unknown
- 1975-09-03 JP JP50106106A patent/JPS6150956B2/ja not_active Expired
- 1975-09-03 AR AR260237A patent/AR222771A1/es active
- 1975-09-03 NL NL7510391.A patent/NL161758C/xx active
- 1975-09-03 DD DD188166A patent/DD123471A5/xx unknown
- 1975-09-03 ES ES440707A patent/ES440707A1/es not_active Expired
1977
- 1977-04-20 ES ES457998A patent/ES457998A1/es not_active Expired
1979
- 1979-08-31 DK DK367279A patent/DK147483C/da active
- 1979-09-14 SE SE7907672A patent/SE435279B/sv not_active IP Right Cessation
1980
- 1980-12-02 CH CH890980A patent/CH636882A5/de not_active IP Right Cessation
1981
- 1981-03-12 CA CA000372811A patent/CA1135254A/en not_active Expired
- 1981-03-12 CA CA372,810A patent/CA1123840A/en not_active Expired
- 1981-08-24 CA CA000384513A patent/CA1135256A/en not_active Expired
- 1981-09-16 YU YU02230/81A patent/YU223081A/xx unknown
- 1981-09-16 YU YU2232/81A patent/YU44669B/xx unknown
- 1981-09-16 YU YU2231/81A patent/YU44964B/xx unknown
- 1981-09-16 YU YU2233/81A patent/YU44833B/xx unknown
1982
- 1982-05-27 DK DK240582A patent/DK148796C/da not_active IP Right Cessation
1983
- 1983-09-16 DK DK423383A patent/DK162388C/da active
- 1983-10-07 SE SE8305539A patent/SE453507B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK148796B (da)	1985-09-30
NO152509B (no)	1985-07-01
FI62841C (fi)	1983-03-10
YU44833B (en)	1991-04-30
YU213275A (en)	1982-02-28
IL48020A (en)	1982-02-28
CH636882A5 (de)	1983-06-30
SE435279B (sv)	1984-09-17
DK391075A (da)	1976-03-04
CA1135254A (en)	1982-11-09
NL161758C (nl)	1980-03-17
FI752434A (xx)	1976-03-04
SE7509702L (sv)	1976-03-04
NO152509C (no)	1985-10-09
DK423383A (da)	1983-09-16
DE2538804A1 (de)	1976-07-15
SE453507B (sv)	1988-02-08
DK145262C (da)	1983-03-14
CA1135256A (en)	1982-11-09
YU223381A (en)	1983-06-30
JPS6150956B2 (xx)	1986-11-06
DK145262B (da)	1982-10-18
DK148796C (da)	1986-03-17
US4297489A (en)	1981-10-27
AR222771A1 (es)	1981-06-30
OA05096A (fr)	1981-01-31
CA1123840A (en)	1982-05-18
BG27091A3 (bg)	1979-08-15
DK162388C (da)	1992-03-16
DE2560655C2 (xx)	1988-07-14
SE8305539D0 (sv)	1983-10-07
DD123471A5 (xx)	1976-12-20
DK367279A (da)	1979-08-31
HU169490B (xx)	1976-12-28
SE431548B (sv)	1984-02-13
YU44964B (en)	1991-06-30
ES457998A1 (es)	1978-03-01
SE8305539L (sv)	1983-10-07
ES440707A1 (es)	1977-07-01
YU223081A (en)	1983-12-31
DE2538804C2 (de)	1986-10-16
SE7907672L (sv)	1979-09-14
NO752983L (xx)	1976-03-04
LU73306A1 (xx)	1976-08-13
YU223281A (en)	1983-12-31
DK162388B (da)	1991-10-21
IL48020A0 (en)	1975-11-25
YU44669B (en)	1990-12-31
FR2283686A1 (fr)	1976-04-02
FI62841B (fi)	1982-11-30
IE43123B1 (en)	1980-12-31
CA1135255A (en)	1982-11-09
FR2283686B1 (xx)	1983-07-08
NL7510391A (nl)	1976-03-05
DK240582A (da)	1982-05-27
DK423383D0 (da)	1983-09-16
YU223181A (en)	1983-12-31
DK147483B (da)	1984-08-27
DK147483C (da)	1985-03-25
IE43123L (en)	1976-03-03
JPS5154580A (xx)	1976-05-13

Publication	Publication Date	Title
AT344906B (de)	1978-08-25	Verfahren zur herstellung neuer cephalosporinverbindungen
NL7500106A (nl)	1975-07-09	Werkwijze ter bereiding van entcopolymeerdisper-
DD129644A5 (de)	1978-02-01	Verfahren zur herstellung neuer prostaglandinvorprodukte
DD110652A5 (de)	1975-01-05	Verfahren zur herstellung neuer 1-aryloxy-2-hydroxy-3-alkinylaminopropane
DD130787A5 (de)	1978-05-03	Verfahren zur herstellung neuer zwischenprodukte fuer neue cephalosporinderivate
AT346592B (de)	1978-11-10	Verfahren zur herstellung neuer konden- sationsprodukte
AT337166B (de)	1977-06-10	Verfahren zur herstellung neuer substituierter benzocycloalkenylalkane
ATA639275A (de)	1977-05-15	Verfahren zur herstellung neuer rifamycine
ATA208576A (de)	1977-02-15	Verfahren zur herstellung neuer alfa-athylbenzhydrol-derivate
ATA845575A (de)	1977-05-15	Verfahren zur herstellung neuer substituierter benzophenone
AT337165B (de)	1977-06-10	Verfahren zur herstellung neuer phenylpropenylaminderivate
ATA986075A (de)	1979-10-15	Verfahren zur herstellung neuer indolderivate
AT338767B (de)	1977-09-12	Verfahren zur herstellung neuer 3-benzoylphenylalkan- oder -alkensauren
BE834514A (nl)	1976-04-15	Werkwijze ter bereiding van dialkanolaminen
DD129783A5 (de)	1978-02-08	Verfahren zur herstellung eines enons
ATA924875A (de)	1979-12-15	Verfahren zur herstellung neuer 5-nitroimida- zolderivate
AT334365B (de)	1976-01-10	Verfahren zur herstellung neuer thiazol-5-methanol-derivate
NL7416719A (nl)	1975-07-04	Werkwijze ter bereiding van s-alkylthiocarba- .
DD122964A5 (de)	1976-11-12	Verfahren zur herstellung von prostensaeurederivaten
AT351525B (de)	1979-07-25	Verfahren zur herstellung neuer thiazol- derivate
DD122968A5 (de)	1976-11-12	Verfahren zur herstellung neuer tetralonderivate
ATA29474A (de)	1975-04-15	Verfahren zur herstellung neuer n-(benzolsulfonyl)-erythromycylaminderivate
ATA435577A (de)	1979-10-15	Verfahren zur herstellung neuer phenylbutenone
AT342201B (de)	1978-03-28	Verfahren zur herstellung neuer cephalosporinverbindungen
ATA376574A (de)	1976-07-15	Verfahren zur herstellung neuer acylderivate des antibiotikums ws-4545