ATE84045T1 - Hemmungsstoffe enkephalinase-b deren herstellung und deren pharmazeutische zusammensetzungen. - Google Patents

Hemmungsstoffe enkephalinase-b deren herstellung und deren pharmazeutische zusammensetzungen.

Info

Publication number
ATE84045T1
ATE84045T1 AT85307127T AT85307127T ATE84045T1 AT E84045 T1 ATE84045 T1 AT E84045T1 AT 85307127 T AT85307127 T AT 85307127T AT 85307127 T AT85307127 T AT 85307127T AT E84045 T1 ATE84045 T1 AT E84045T1
Authority
AT
Austria
Prior art keywords
enkephalinase
preparation
pharmaceutical compositions
inhibiting substances
kitasatosporia
Prior art date
Application number
AT85307127T
Other languages
English (en)
Inventor
Yoshinori Inaoka
Hidetsune Tamaoki
Syuji Takahashi
Ryuzo Enokita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE84045T1 publication Critical patent/ATE84045T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT85307127T 1984-10-04 1985-10-04 Hemmungsstoffe enkephalinase-b deren herstellung und deren pharmazeutische zusammensetzungen. ATE84045T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59208789A JPS6188884A (ja) 1984-10-04 1984-10-04 エンケフアリナ−ゼｂ阻害物質およびその製法
EP85307127A EP0177366B1 (de) 1984-10-04 1985-10-04 Hemmungsstoffe Enkephalinase-B deren Herstellung und deren pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE84045T1 true ATE84045T1 (de) 1993-01-15

Family

ID=16562134

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85307127T ATE84045T1 (de) 1984-10-04 1985-10-04 Hemmungsstoffe enkephalinase-b deren herstellung und deren pharmazeutische zusammensetzungen.

Country Status (7)

Country Link
US (1) US4804676A (de)
EP (1) EP0177366B1 (de)
JP (1) JPS6188884A (de)
AT (1) ATE84045T1 (de)
CA (1) CA1277623C (de)
DE (1) DE3586935T2 (de)
ES (1) ES8701228A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2746372B2 (ja) * 1988-03-11 1998-05-06 科研製薬株式会社 Ｆ−０３６８物質
US6362341B1 (en) 1997-07-31 2002-03-26 Athena Neurosciences, Inc. Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4
US6492421B1 (en) 1997-07-31 2002-12-10 Athena Neurosciences, Inc. Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
US7030114B1 (en) 1997-07-31 2006-04-18 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6423688B1 (en) * 1997-07-31 2002-07-23 Athena Neurosciences, Inc. Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
US6583139B1 (en) * 1997-07-31 2003-06-24 Eugene D. Thorsett Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6559127B1 (en) 1997-07-31 2003-05-06 Athena Neurosciences, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6939855B2 (en) 1997-07-31 2005-09-06 Elan Pharmaceuticals, Inc. Anti-inflammatory compositions and method
CA2393825A1 (en) * 1999-12-17 2001-06-21 Versicor, Inc. Novel succinate compounds, compositions and methods of use and preparation
US6797820B2 (en) 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
US20040006093A1 (en) * 2000-10-17 2004-01-08 Thorsett Eugene D. Compounds which inhibit leukocyte adhesion mediated by VLA-4
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
CA2446931A1 (en) * 2001-06-15 2002-12-27 Vicuron Pharmaceuticals Inc. Pyrrolidine bicyclic compounds
GB0509223D0 (en) 2005-05-05 2005-06-15 Chroma Therapeutics Ltd Enzyme inhibitors
KR20240122910A (ko) 2016-04-21 2024-08-13 4틴4 파마슈티컬스 게엠베하 Dpp3을 결정하는 방법 및 치료 방법
AU2018356441A1 (en) 2017-10-25 2020-04-16 4TEEN4 Pharmaceuticals GmbH DPP3 binder directed to and binding to specific DPP3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress
US20230213519A1 (en) 2020-03-16 2023-07-06 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
EP3922993A1 (de) 2020-06-12 2021-12-15 4TEEN4 Pharmaceuticals GmbH Dpp3 bei patienten, die mit coronavirus infiziert sind
WO2024126793A1 (en) 2022-12-15 2024-06-20 4TEEN4 Pharmaceuticals GmbH Dpp3 inhibitor for improvement of pulmonary function in critically ill patients
WO2024200862A1 (en) 2023-03-29 2024-10-03 4TEEN4 Pharmaceuticals GmbH Dpp3 inhibitor for myocardial protection and prevention of myocardial injury in critically ill patients with blood pressure decline

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284561A (en) * 1979-12-03 1981-08-18 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of mercaptoacyl amino acids
JPS5697266A (en) * 1979-12-28 1981-08-05 Tanabe Seiyaku Co Ltd Proline derivative and its preparation
JPS56139455A (en) * 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
FR2518088B1 (fr) * 1981-12-16 1987-11-27 Roques Bernard Nouveaux derives d'aminoacides, et leur application therapeutique
JPS6115840A (ja) * 1984-07-03 1986-01-23 Microbial Chem Res Found 免疫賦活剤

Also Published As

Publication number Publication date
EP0177366A3 (en) 1988-08-10
ES547630A0 (es) 1986-11-16
DE3586935D1 (de) 1993-02-11
JPS6188884A (ja) 1986-05-07
EP0177366A2 (de) 1986-04-09
CA1277623C (en) 1990-12-11
EP0177366B1 (de) 1992-12-30
JPH0413358B2 (de) 1992-03-09
DE3586935T2 (de) 1993-07-22
US4804676A (en) 1989-02-14
ES8701228A1 (es) 1986-11-16

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee