ATE68471T1 - Gem-dihalo-1,8-diamino-4-aza-oktane. - Google Patents

Gem-dihalo-1,8-diamino-4-aza-oktane.

Info

Publication number
ATE68471T1
ATE68471T1 AT86111503T AT86111503T ATE68471T1 AT E68471 T1 ATE68471 T1 AT E68471T1 AT 86111503 T AT86111503 T AT 86111503T AT 86111503 T AT86111503 T AT 86111503T AT E68471 T1 ATE68471 T1 AT E68471T1
Authority
AT
Austria
Prior art keywords
octanes
dihalo
gem
aza
diamino
Prior art date
Application number
AT86111503T
Other languages
English (en)
Inventor
Fritz Gerhart
Pierre Mamont
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE68471T1 publication Critical patent/ATE68471T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
AT86111503T 1985-08-21 1986-08-20 Gem-dihalo-1,8-diamino-4-aza-oktane. ATE68471T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/767,928 US4695654A (en) 1985-08-21 1985-08-21 Gem-dihalo-1,8-diamino-4-aza-octanes
EP86111503A EP0215319B1 (de) 1985-08-21 1986-08-20 Gem-Dihalo-1,8-diamino-4-aza-oktane

Publications (1)

Publication Number Publication Date
ATE68471T1 true ATE68471T1 (de) 1991-11-15

Family

ID=25080994

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86111503T ATE68471T1 (de) 1985-08-21 1986-08-20 Gem-dihalo-1,8-diamino-4-aza-oktane.

Country Status (20)

Country Link
US (2) US4695654A (de)
EP (1) EP0215319B1 (de)
JP (1) JPH0667880B2 (de)
KR (1) KR900006132B1 (de)
CN (1) CN1012732B (de)
AR (1) AR242018A1 (de)
AT (1) ATE68471T1 (de)
AU (1) AU584730B2 (de)
CA (1) CA1265159C (de)
DE (1) DE3682007D1 (de)
DK (1) DK396886A (de)
ES (1) ES2001108A6 (de)
FI (1) FI84816C (de)
GR (1) GR862149B (de)
HU (1) HU200987B (de)
IL (1) IL79752A0 (de)
NO (1) NO164972C (de)
NZ (1) NZ217248A (de)
PT (1) PT83231B (de)
ZA (1) ZA866181B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA866180B (en) * 1985-08-21 1987-04-29 Merrell Dow Pharma Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes
NO884565L (no) * 1987-10-15 1989-04-17 Univ Moskovsk Preparat for kontrastdannelse ved diagnose av ondartet neoplasma.
EP0338168A1 (de) * 1988-04-19 1989-10-25 Merrell Dow Pharmaceuticals Inc. Phosphonoalkylpurin-Derivate
GB9301898D0 (en) * 1993-01-30 1993-03-17 Univ Liverpool Method for localising and measuring the profileration of cancer and compositions for same
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
CN114685325B (zh) * 2020-12-29 2024-05-28 苏州瑞博生物技术股份有限公司 一种含胺化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004996A (en) * 1974-12-23 1977-01-25 Merck & Co., Inc. Fluorination of organic compounds
GB2082579B (en) * 1980-08-23 1984-02-08 Merrell Toraude & Co Fluorinated diaminobutane derivatives
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
ZA866180B (en) * 1985-08-21 1987-04-29 Merrell Dow Pharma Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes

Also Published As

Publication number Publication date
CN1012732B (zh) 1991-06-05
JPS6245564A (ja) 1987-02-27
ZA866181B (en) 1987-04-29
HU200987B (en) 1990-09-28
NZ217248A (en) 1989-05-29
NO863343D0 (no) 1986-08-20
FI84816C (fi) 1992-01-27
CN86105154A (zh) 1987-04-22
DK396886A (da) 1987-02-22
EP0215319B1 (de) 1991-10-16
EP0215319A2 (de) 1987-03-25
NO164972B (no) 1990-08-27
DE3682007D1 (de) 1991-11-21
AU584730B2 (en) 1989-06-01
KR900006132B1 (ko) 1990-08-24
NO164972C (no) 1990-12-05
IL79752A0 (en) 1986-11-30
FI863352A0 (fi) 1986-08-19
AR242018A1 (es) 1993-02-26
FI863352A (fi) 1987-02-22
CA1265159A (en) 1990-01-30
CA1265159C (en) 1990-01-30
AU6155886A (en) 1987-02-26
JPH0667880B2 (ja) 1994-08-31
FI84816B (fi) 1991-10-15
EP0215319A3 (en) 1988-12-14
ES2001108A6 (es) 1988-04-16
NO863343L (no) 1987-02-23
KR870002045A (ko) 1987-03-28
PT83231B (pt) 1988-07-01
GR862149B (en) 1986-12-23
DK396886D0 (da) 1986-08-20
US4695654A (en) 1987-09-22
PT83231A (en) 1986-09-01
HUT44753A (en) 1988-04-28
US4851448A (en) 1989-07-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee