ATE245196T1 - Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta - Google Patents

Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta

Info

Publication number
ATE245196T1
ATE245196T1 AT94911509T AT94911509T ATE245196T1 AT E245196 T1 ATE245196 T1 AT E245196T1 AT 94911509 T AT94911509 T AT 94911509T AT 94911509 T AT94911509 T AT 94911509T AT E245196 T1 ATE245196 T1 AT E245196T1
Authority
AT
Austria
Prior art keywords
growth factor
transforming growth
factor beta
fertility
regulation
Prior art date
Application number
AT94911509T
Other languages
English (en)
Inventor
Ronald F Feinberg
Harvey Jon Kliman
Original Assignee
Univ Pennsylvania
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania, Univ Yale filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE245196T1 publication Critical patent/ATE245196T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/495—Transforming growth factor [TGF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/806—Fertility tests
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/814—Pregnancy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/906—Fertility tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94911509T 1993-03-10 1994-03-08 Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta ATE245196T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/029,027 US5395825A (en) 1993-03-10 1993-03-10 Fertility regulation with transforming growth factor β
PCT/US1994/002527 WO1994020637A1 (en) 1993-03-10 1994-03-08 Fertility regulation with transforming growth factor beta

Publications (1)

Publication Number Publication Date
ATE245196T1 true ATE245196T1 (de) 2003-08-15

Family

ID=21846834

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94911509T ATE245196T1 (de) 1993-03-10 1994-03-08 Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta

Country Status (9)

Country Link
US (2) US5395825A (de)
EP (1) EP0688365B1 (de)
JP (1) JPH08507530A (de)
AT (1) ATE245196T1 (de)
AU (1) AU676727B2 (de)
CA (1) CA2156613A1 (de)
DE (1) DE69432951T2 (de)
DK (1) DK0688365T3 (de)
WO (1) WO1994020637A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5508045A (en) * 1992-10-09 1996-04-16 The Regents Of The University Of California Method and agents for control and management of labor during pregnancy
US5830848A (en) * 1992-10-09 1998-11-03 The Regents Of The University Of California Method and agents for inducement of endogenous nitric oxide synthase for control and management of labor during pregnancy
US5395825A (en) * 1993-03-10 1995-03-07 Yale University Fertility regulation with transforming growth factor β
US5599918A (en) * 1994-10-04 1997-02-04 La Jolla Cancer Research Foundation Nucleic acids encoding trophinin and trophinin-assisting proteins
US5654145A (en) * 1994-10-04 1997-08-05 La Jolla Cancer Research Foundation Trophinin and trophinin-assisting nucleic acids and methods of detection thereof
US6309843B1 (en) 1994-10-25 2001-10-30 The Curators Of The University Of Missouri Glycoprotein for use in determining endometrial receptivity
US8106001B2 (en) * 1996-08-27 2012-01-31 University Of South Florida Diagnostic markers of human female infertility
US6294662B1 (en) 1996-08-27 2001-09-25 University Of South Florida Nucleic acids encoding an endometrial bleeding associated factor (ebaf)
US7211644B1 (en) * 1996-08-27 2007-05-01 University Of South Florida Diagnostic markers of human female infertility
US6683156B1 (en) 1996-08-27 2004-01-27 University Of South Florida Method for diagnosing selected adenocarcinomas
WO1999055902A1 (en) * 1998-04-29 1999-11-04 University Of South Florida Diagnostic markers of human female infertility
AUPO550897A0 (en) * 1997-03-06 1997-03-27 Luminis Pty Limited Treatment and diagnosis of an infertility condition
AU722150B2 (en) * 1997-03-06 2000-07-20 University Of Adelaide, The Treatment and diagnosis of infertility using TGFbeta or activin
US6300311B1 (en) 1998-04-14 2001-10-09 Texas Tech University Regulation of vertebrate ovarian maturation and function using growth factors
GB0201284D0 (en) * 2002-01-21 2002-03-06 Isis Innovation Screening methods for contraceptive and fertility agents
US7572639B2 (en) * 2004-06-03 2009-08-11 Stc.Unm Method and apparatus for predicting pregnancy outcome
JP2008514900A (ja) 2004-07-30 2008-05-08 アデザ・バイオメデイカル・コーポレイシヨン 疾病および他の状態のマーカーとしての癌胎児性フィブロネクチンならびに癌胎児性フィブロネクチンの検出のための方法
WO2011002251A2 (ko) * 2009-07-01 2011-01-06 중앙대학교 산학협력단 수태능력 예측용 마커
GB201314452D0 (en) * 2013-08-13 2013-09-25 Ostara Biomedical Ltd Embryo implantation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104977A (en) * 1982-09-24 1992-04-14 The United States Of America As Represented By The Department Of Health And Human Services Purified transforming growth factor beta
US4894326A (en) * 1986-04-09 1990-01-16 Fred Hutchinson Cancer Research Center Monoclonal antibody defining oncofetal structure of fibronectin
US5098890A (en) * 1988-11-07 1992-03-24 Temple University-Of The Commonwealth System Of Higher Education Antisence oligonucleotides to c-myb proto-oncogene and uses thereof
US5158934A (en) * 1989-09-01 1992-10-27 Genentech, Inc. Method of inducing bone growth using TGF-β
DK0494264T3 (da) * 1989-09-29 1998-01-26 Jolla Cancer Res Found Inhibering af transformede vækstfaktor til hindring af akkumulation af ekstracellulær matrix
US5276017A (en) * 1990-09-14 1994-01-04 Trustees Of The University Of Pennsylvania Therapeutic and diagnostic applications of tropho-uteronectin (TUN) manipulation
US5395825A (en) * 1993-03-10 1995-03-07 Yale University Fertility regulation with transforming growth factor β
FR2720069A1 (fr) * 1994-05-19 1995-11-24 Inst Nat Sante Rech Med Dérivés de facteurs de croissance et d'hormones de la superfamille des TGFB, procédé pour leur obtention et leurs applications biologiques.

Also Published As

Publication number Publication date
EP0688365B1 (de) 2003-07-16
EP0688365A4 (de) 1997-06-25
CA2156613A1 (en) 1994-09-15
EP0688365A1 (de) 1995-12-27
JPH08507530A (ja) 1996-08-13
AU6399894A (en) 1994-09-26
WO1994020637A1 (en) 1994-09-15
DE69432951T2 (de) 2004-05-13
DE69432951D1 (de) 2003-08-21
DK0688365T3 (da) 2003-09-29
US5395825A (en) 1995-03-07
AU676727B2 (en) 1997-03-20
US5693479A (en) 1997-12-02

Similar Documents

Publication Publication Date Title
ATE245196T1 (de) Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta
MY102705A (en) Proline derivaties and related compounds.
PL331091A1 (en) Therapeutic multispecific compounds encompassing antibodies against the fcalpha receptor
ZA946142B (en) Therapeutic heterocycles
IT1217438B (it) Tubazione per autoveicolo,per la conduzione di un mezzo alcoolico
BG102999A (en) New 2,3-diasubstituted-4-(3h)-quinazolinons
ES466793A1 (es) Un procedimiento para la preparacion de derivados de imida- zol, con propiedades antiartriticas.
EP0521842A3 (de)
ES2023977B3 (es) Procedimiento para la obtencion de helio.
BG40815A3 (en) Method for preparing peptides
ZA844603B (en) Novel 1-alkyl-androsta-1,4-diene-3,17-diones and their manufacture and use
HK1002659A1 (en) Intracelluilar isoform of the interleukin-1 receptor antagonist
BG36928A3 (en) Method for preparing pharmacologically active peptides
IT8520630A0 (it) Dispositivo di regolazione ortopedico per la mascella.
MX9303843A (es) 4-iminoquinolinas, procedimiento para su preparacion y su empleo.
HU9203838D0 (en) Method for producing isohirudin of improved stability
AU1097988A (en) Alkylmelatonins
ATE227122T1 (de) Stabilisierte tablettenformulierung
ES8205218A1 (es) Un procedimiento para la preparacion de pirrolilpiperidinas utiles como agentes antidepresivo.
ES8400401A1 (es) "un procedimiento para preparar un 1,4-dialcohilo inferior-3-alcoxicarbonilo inferior-pirrol-2-acetato de alcohilo inferior".
GR3005231T3 (de)
MX9300677A (es) Procedimiento mejorado para la preparacion de dienos esteroidales substituidos.
JPS6485998A (en) Acylated splenopentine, manufacture and use
SU887878A1 (ru) Демпфирующее устройство
FI890173A (fi) Isoxazoler med nootropisk verkan.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties