AR198064A1 - Sintesis de nuevos derivados del del acido heterociclico-indol-3-il-carboxilico - Google Patents
Sintesis de nuevos derivados del del acido heterociclico-indol-3-il-carboxilicoInfo
- Publication number
- AR198064A1 AR198064A1 AR244863A AR24486372A AR198064A1 AR 198064 A1 AR198064 A1 AR 198064A1 AR 244863 A AR244863 A AR 244863A AR 24486372 A AR24486372 A AR 24486372A AR 198064 A1 AR198064 A1 AR 198064A1
- Authority
- AR
- Argentina
- Prior art keywords
- indol
- carboxyl
- synthesis
- new derivatives
- heterocyclic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1811672A GB1356834A (en) | 1971-11-03 | 1971-11-03 | Indole derivatives |
| GB1811672 | 1972-04-19 | ||
| GB3076772 | 1972-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR198064A1 true AR198064A1 (es) | 1974-05-31 |
Family
ID=27257588
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR244863A AR198064A1 (es) | 1971-11-03 | 1972-10-27 | Sintesis de nuevos derivados del del acido heterociclico-indol-3-il-carboxilico |
| AR249381A AR203626A1 (es) | 1971-11-03 | 1973-07-31 | Sintesis de nuevos acidos heterociclico-indol-3-ii-acetic |
| AR249382A AR203627A1 (es) | 1971-11-03 | 1973-07-31 | Sintesis de nuevos derivados del acido heterociclico-indol-3-ilacetico |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR249381A AR203626A1 (es) | 1971-11-03 | 1973-07-31 | Sintesis de nuevos acidos heterociclico-indol-3-ii-acetic |
| AR249382A AR203627A1 (es) | 1971-11-03 | 1973-07-31 | Sintesis de nuevos derivados del acido heterociclico-indol-3-ilacetico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3884919A (es) |
| JP (1) | JPS4856667A (es) |
| AR (3) | AR198064A1 (es) |
| BE (1) | BE790679A (es) |
| CA (1) | CA983932A (es) |
| CH (1) | CH577499A5 (es) |
| DD (1) | DD105611A5 (es) |
| DE (1) | DE2253927A1 (es) |
| EG (1) | EG11358A (es) |
| ES (2) | ES408226A1 (es) |
| FR (1) | FR2158464B1 (es) |
| GB (1) | GB1356834A (es) |
| HU (1) | HU169711B (es) |
| IE (1) | IE37998B1 (es) |
| IL (1) | IL40521A (es) |
| NL (1) | NL7214807A (es) |
| SE (1) | SE384856B (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022780A (en) * | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
| FR2421900A1 (fr) * | 1977-03-17 | 1979-11-02 | Sauba Lab | Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques |
| US4316847A (en) * | 1979-07-30 | 1982-02-23 | Hoffmann-La Roche Inc. | Pyrroles and pyrrolidines |
| US4459227A (en) * | 1981-03-02 | 1984-07-10 | Duke University | Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones |
| AU686843B2 (en) * | 1994-02-23 | 1998-02-12 | Pfizer Inc. | 4-heterocyclyl-substituted quinazoline derivatives, processes for their preparation and their use as anti-cancer agents |
| US6252084B1 (en) * | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
| EA003876B1 (ru) * | 1998-02-25 | 2003-10-30 | Дженетикс Инститьют, Ллс | Ингибиторы фосфолипазных ферментов |
| US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| SE0200356D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) * | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| DK1471057T3 (da) | 2003-04-25 | 2006-05-15 | Actimis Pharmaceuticals Inc | Pyrimidinyleddikesyrederivater, der er egnede til behandlingen af sygdomme medieret af CRTH2 |
| ATE372324T1 (de) * | 2003-04-30 | 2007-09-15 | Inst For Pharm Discovery Inc | Substituierte heteroarylverbindungen als inhibitoren von proteintyrosinphosphatasen |
| SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
| CN100584844C (zh) | 2004-01-31 | 2010-01-27 | 艾克提麦斯医药品有限公司 | 咪唑[1,2-c]嘧啶基乙酸衍生物 |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
| EP1937632A1 (en) | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| CN101454284A (zh) | 2006-05-26 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
| SI2046740T1 (sl) | 2006-07-22 | 2012-12-31 | Oxagen Limited | Spojine s crth2 antagonistiäśno aktivnostjo |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| KR20100061746A (ko) | 2007-09-25 | 2010-06-08 | 액티미스 파마수티컬스 인코포레이티드 | Ｃｒｔｈ２ 길항제로서의 ２－ｓ－벤질 치환된 피리미딘 |
| SI2205569T1 (sl) | 2007-09-25 | 2012-06-29 | Actimis Pharmaceuticals Inc | Alkiltio pirimidini kot crth2 antagonisti |
| US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| CA2712017C (en) | 2008-01-18 | 2016-08-09 | Oxagen Limited | Compounds having crth2 antagonist activity |
| JP2011509991A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
| GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| KR20210089656A (ko) * | 2018-10-05 | 2021-07-16 | 버텍스 파마슈티칼스 인코포레이티드 | 알파-1 항트립신 조절제 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL125443C (es) * | 1963-06-06 | |||
| US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
-
0
- BE BE790679D patent/BE790679A/xx unknown
-
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
-
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx not_active IP Right Cessation
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
-
1973
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
-
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AR203627A1 (es) | 1975-09-30 |
| US3884919A (en) | 1975-05-20 |
| GB1356834A (en) | 1974-06-19 |
| IE37998B1 (en) | 1977-12-07 |
| IL40521A0 (en) | 1972-12-29 |
| FR2158464B1 (es) | 1976-07-02 |
| CA983932A (en) | 1976-02-17 |
| ES437311A1 (es) | 1977-04-01 |
| IL40521A (en) | 1975-06-25 |
| CH577499A5 (es) | 1976-07-15 |
| AR203626A1 (es) | 1975-09-30 |
| SE384856B (sv) | 1976-05-24 |
| NL7214807A (es) | 1973-05-07 |
| HU169711B (es) | 1977-02-28 |
| EG11358A (en) | 1977-02-28 |
| FR2158464A1 (es) | 1973-06-15 |
| ES408226A1 (es) | 1976-02-01 |
| IE37998L (en) | 1973-05-03 |
| JPS4856667A (es) | 1973-08-09 |
| BE790679A (fr) | 1973-04-27 |
| DD105611A5 (es) | 1974-05-05 |
| DE2253927A1 (de) | 1973-05-10 |
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