NTR: peroxisomal-mitochondrial tether activity

[robnash]

Please provide as much information as you can:

• Suggested term label:

peroxisomal-mitochondrial tether activity

• Definition (free text)

The binding activity of a molecule that brings together a peroxisomal and mitochondrial membrane either via membrane lipid binding or by interacting with a mitochondrial protein, to establish and facilitate organelle exchange, such as the transit of peroxisomal citrate into mitochondria

• Reference, in format PMID:#######

PMID: 29720625
PMID: 38669296

• Gene product name and ID to be annotated to this term

FZO1 and PEX34 (S. cerevisiae)

• Parent term(s)

GO:0043495 protein-membrane adaptor activity

• Children terms (if applicable) Should any existing terms that should be moved underneath this new proposed term?

• Synonyms (please specify, EXACT, BROAD, NARROW or RELATED)

PerMit contact activity (EXACT)

• Cross-references

• For enzymes, please provide RHEA and/or EC numbers.

• Can also provide MetaCyc, KEGG, Wikipedia, and other links.

• Any other information

[robnash]

Thanks Raymond :)

[raymond91125]

+[Term]
+id: GO:0160190
+name: peroxisome-mitochondrion membrane tether activity
+namespace: molecular_function
+def: "The binding activity of a molecule that brings together the peroxisome and the mitochondrial outer membrane, establishing the localization of the peroxisome close to the mitochondrion." [PMID:29720625, PMID:38669296]
+is_a: GO:0043495 ! protein-membrane adaptor activity
+property_value: term_tracker_item "#28255" xsd:anyURI
+created_by: rynl
+creation_date: 2024-06-24T22:53:31Z