NTR: inositol pyrophosphate sensor activity

[ValWood]

Please provide as much information as you can:

• Suggested term label:

inositol pyrophosphate sensor activity

• Definition (free text)

Binding to and responding, e.g. by conformational change, to changes in the cellular level of an inositol pyrophosphate

• Reference, in format PMID:#######

PMID:37949217

Abstract
"SPX domains bind to inositol pyrophosphate and modulate activities of Pi-related proteins."

Results
" The SPX domain reportedly functions as a Pi sensor and to bind signaling molecules, PP- IPs, like IP7 and IP8 (21). "

• Gene product name and ID to be annotated to this term

initially fission yeast spx2 but potentially any SPX domain protein

https://www.pombase.org/gene_subset/interpro:IPR004331

• Parent term(s)

GO:0140299 small molecule sensor activity

• Synonyms (please specify, EXACT, BROAD, NARROW or RELATED)

inositol hexakisphosphate sensor (narrow)
because I think most use GO:0000822 JSON
inositol hexakisphosphate binding

• Cross-references

• For enzymes, please provide RHEA and/or EC numbers.

• Can also provide MetaCyc, KEGG, Wikipedia, and other links.

• Any other information

[ValWood]

+[Term]
+id: GO:0180041
+name: polyphosphate import into vacuole
+namespace: biological_process
+comment: The process in which a polyphosphate is transported across the vacuolar membrane from the cytoplasm to the vacuole. {xref="GOC:vw"}
+is_a: GO:0034486 ! vacuolar transmembrane transport
+created_by: vw
+creation_date: 2024-05-21T13:43:18Z

[ValWood]

+[Term]
+id: GO:0180043
+name: inositol pyrophosphate sensor activity
+namespace: molecular_function
949217]

[ValWood]

This

+id: GO:0180043
+name: inositol pyrophosphate sensor activity
+namespace: molecular_function
949217]

did not apepar which is odd because the other changes I did at the same time were fine. Will look tomorrow...