COPS2

COPS2
COPS2
사용 가능한 구조
PDB휴먼 유니프로트 검색: PDBe RCSB
식별자
에일리어스COPS2, ALIN, CSN2, SGN2, TRIP15, COP9 시그널로솜 서브유닛2
외부 IDOMIM: 604508 HomoloGene: 134283 GenCard: COPS2
맞춤법
종.인간마우스
엔트레즈
앙상블
유니프로트
RefSeq(mRNA)

NM_004236
NM_001143887

없음

RefSeq(단백질)

NP_001137359
NP_004227

없음

장소(UCSC)Chr 15: 49.11 ~49.16 Mb없음
PubMed 검색[2]없음
위키데이터
인간 보기/편집

COP9시그널로솜복합체 서브유닛2COPS2유전자[3][4][5]의해 인체 내에서 부호화되는 단백질이다.COP9 시그널로좀의 서브유닛을 부호화합니다.

상호 작용

COPS2는 다음과 상호작용하는 으로 나타났습니다.

레퍼런스

  1. ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG0000016ucc - Ensembl, 2017년 5월
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (July 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol. 9 (2): 243–54. doi:10.1210/mend.9.2.7776974. PMID 7776974.
  4. ^ Seeger M, Kraft R, Ferrell K, Bech-Otschir D, Dumdey R, Schade R, Gordon C, Naumann M, Dubiel W (April 1998). "A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits". FASEB J. 12 (6): 469–78. doi:10.1096/fasebj.12.6.469. PMID 9535219. S2CID 25424324.
  5. ^ "Entrez Gene: COPS2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)".
  6. ^ Altincicek B, Tenbaum SP, Dressel U, Thormeyer D, Renkawitz R, Baniahmad A (March 2000). "Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita". J. Biol. Chem. 275 (11): 7662–7. doi:10.1074/jbc.275.11.7662. PMID 10713076.
  7. ^ Cohen H, Azriel A, Cohen T, Meraro D, Hashmueli S, Bech-Otschir D, Kraft R, Dubiel W, Levi BZ (December 2000). "Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome". J. Biol. Chem. 275 (50): 39081–9. doi:10.1074/jbc.M004900200. PMID 10991940.
  8. ^ Akiyama H, Fujisawa N, Tashiro Y, Takanabe N, Sugiyama A, Tashiro F (March 2003). "The role of transcriptional corepressor Nif3l1 in early stage of neural differentiation via cooperation with Trip15/CSN2". J. Biol. Chem. 278 (12): 10752–62. doi:10.1074/jbc.M209856200. PMID 12522100.
  9. ^ Dressel U, Thormeyer D, Altincicek B, Paululat A, Eggert M, Schneider S, Tenbaum SP, Renkawitz R, Baniahmad A (May 1999). "Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily". Mol. Cell. Biol. 19 (5): 3383–94. doi:10.1128/mcb.19.5.3383. PMC 84131. PMID 10207062.

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