KEGG   PATHWAY: syun00230
Entry
syun00230                   Pathway                                
Name
Purine metabolism - Streptomyces yunnanensis
Class
Metabolism; Nucleotide metabolism
Pathway map
syun00230  Purine metabolism
syun00230

Module
syun_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:syun00230]
syun_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:syun00230]
syun_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:syun00230]
syun_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:syun00230]
syun_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:syun00230]
syun_M00546  Purine degradation, xanthine => urea [PATH:syun00230]
syun_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:syun00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces yunnanensis [GN:syun]
Gene
MOV08_25020  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
MOV08_22680  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MOV08_22610  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MOV08_17235  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MOV08_22670  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
MOV08_22660  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MOV08_22665  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MOV08_22685  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MOV08_25390  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MOV08_25395  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MOV08_22635  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MOV08_05925  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MOV08_17230  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MOV08_33245  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MOV08_32735  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
MOV08_18340  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
MOV08_26410  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
MOV08_16660  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MOV08_29985  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MOV08_06685  nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
MOV08_19090  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MOV08_23990  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MOV08_23995  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
MOV08_27360  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MOV08_22325  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MOV08_26245  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MOV08_39540  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MOV08_11310  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MOV08_39545  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
MOV08_11315  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
MOV08_39550  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
MOV08_11320  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
MOV08_17500  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
MOV08_33495  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
MOV08_33430  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MOV08_12570  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
MOV08_15185  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MOV08_15190  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MOV08_28105  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
MOV08_33250  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MOV08_12625  HD domain-containing protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MOV08_25190  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MOV08_18815  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MOV08_16580  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MOV08_27910  CYTH domain-containing protein [KO:K05873] [EC:4.6.1.1]
MOV08_22575  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
MOV08_29610  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
MOV08_23600  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MOV08_36370  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MOV08_07895  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MOV08_16775  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MOV08_28090  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
MOV08_30345  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
MOV08_23795  adenylate kinase [KO:K00939] [EC:2.7.4.3]
MOV08_33155  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
MOV08_11430  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
MOV08_11440  GTP-binding protein [KO:K00956] [EC:2.7.7.4]
MOV08_11435  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
MOV08_10960  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
MOV08_10965  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MOV08_10970  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
MOV08_16960  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
MOV08_10880  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
MOV08_10870  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
MOV08_27205  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
MOV08_10865  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
MOV08_01690  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MOV08_05765  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MOV08_07205  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MOV08_13830  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MOV08_05775  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
MOV08_01685  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
MOV08_07210  urease subunit gamma [KO:K14048] [EC:3.5.1.5]
MOV08_13835  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
syun00030  Pentose phosphate pathway
syun00220  Arginine biosynthesis
syun00250  Alanine, aspartate and glutamate metabolism
syun00260  Glycine, serine and threonine metabolism
syun00340  Histidine metabolism
syun00630  Glyoxylate and dicarboxylate metabolism
syun00730  Thiamine metabolism
syun00740  Riboflavin metabolism
syun00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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