KEGG   PATHWAY: mvt00010
Entry
mvt00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Mammaliicoccus vitulinus
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
mvt00010  Glycolysis / Gluconeogenesis
mvt00010

Module
mvt_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:mvt00010]
mvt_M00002  Glycolysis, core module involving three-carbon compounds [PATH:mvt00010]
mvt_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:mvt00010]
mvt_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:mvt00010]
Other DBs
GO: 0006096 0006094
Organism
Mammaliicoccus vitulinus [GN:mvt]
Gene
I6J10_05190  ROK family glucokinase [KO:K25026] [EC:2.7.1.2]
I6J10_01870  glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
I6J10_05980  pfkA; 6-phosphofructokinase [KO:K00850] [EC:2.7.1.11]
I6J10_09725  fructose-1,6-bisphosphatase [KO:K04041] [EC:3.1.3.11]
I6J10_10160  fructose bisphosphate aldolase [KO:K01623] [EC:4.1.2.13]
I6J10_00105  ketose-bisphosphate aldolase [KO:K01624] [EC:4.1.2.13]
I6J10_07980  fructose-bisphosphate aldolase [KO:K01624] [EC:4.1.2.13]
I6J10_01270  triose-phosphate isomerase [KO:K01803] [EC:5.3.1.1]
I6J10_01260  gap; type I glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
I6J10_05925  glyceraldehyde-3-phosphate dehydrogenase [KO:K00150] [EC:1.2.1.59]
I6J10_01265  phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
I6J10_09630  2,3-diphosphoglycerate-dependent phosphoglycerate mutase [KO:K01834] [EC:5.4.2.11]
I6J10_01275  2,3-bisphosphoglycerate-independent phosphoglycerate mutase [KO:K15633] [EC:5.4.2.12]
I6J10_01280  eno; phosphopyruvate hydratase [KO:K01689] [EC:4.2.1.11]
I6J10_05975  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
I6J10_02640  pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [KO:K00161] [EC:1.2.4.1]
I6J10_02645  alpha-ketoacid dehydrogenase subunit beta [KO:K00162] [EC:1.2.4.1]
I6J10_02650  2-oxo acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
I6J10_02655  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
I6J10_05010  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
I6J10_03840  2-oxoacid:acceptor oxidoreductase subunit alpha [KO:K00174] [EC:1.2.7.3 1.2.7.11]
I6J10_03845  2-oxoacid:ferredoxin oxidoreductase subunit beta [KO:K00175] [EC:1.2.7.3 1.2.7.11]
I6J10_09425  L-lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
I6J10_10745  NAD(P)-dependent alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
I6J10_07965  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
I6J10_00780  aldehyde dehydrogenase [KO:K00138] [EC:1.2.1.-]
I6J10_06170  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
I6J10_10325  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
I6J10_12535  hypothetical protein [KO:K01785] [EC:5.1.3.3]
I6J10_00220  phospho-sugar mutase [KO:K01835] [EC:5.4.2.2]
I6J10_06520  pckA; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
I6J10_09775  6-phospho-beta-glucosidase [KO:K01223] [EC:3.2.1.86]
I6J10_10730  ascB; 6-phospho-beta-glucosidase [KO:K01223] [EC:3.2.1.86]
I6J10_12590  glycoside hydrolase family 1 protein [KO:K01223] [EC:3.2.1.86]
I6J10_04550  PTS glucose transporter subunit IIA [KO:K02777] [EC:2.7.1.-]
I6J10_03555  malX; PTS maltose transporter subunit IICB [KO:K02791] [EC:2.7.1.199 2.7.1.208]
I6J10_12055  PTS transporter subunit EIIC [KO:K02791] [EC:2.7.1.199 2.7.1.208]
I6J10_04205  PTS transporter subunit IIABC [KO:K20118] [EC:2.7.1.199]
I6J10_10735  ascF; PTS cellobiose/arbutin/salicin transporter subunit IIBC [KO:K02753] [EC:2.7.1.-]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
mvt00020  Citrate cycle (TCA cycle)
mvt00030  Pentose phosphate pathway
mvt00500  Starch and sucrose metabolism
mvt00620  Pyruvate metabolism
mvt00640  Propanoate metabolism
mvt00710  Carbon fixation by Calvin cycle
KO pathway
ko00010   
LinkDB

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