KEGG   Crotalus tigris (Tiger rattlesnake): 120305320
Entry
120305320         CDS       T08476                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
ctig  Crotalus tigris (Tiger rattlesnake)
Pathway
ctig00670  One carbon pool by folate
ctig01100  Metabolic pathways
ctig01240  Biosynthesis of cofactors
ctig04981  Folate transport and metabolism
Module
ctig_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ctig00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    120305320 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    120305320 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ctig04147]
    120305320 (MTHFD1)
Enzymes [BR:ctig01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     120305320 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     120305320 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     120305320 (MTHFD1)
Exosome [BR:ctig04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   120305320 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 120305320
NCBI-ProteinID: XP_039192931
LinkDB
Position
Unknown
AA seq 935 aa
MPSAEIISGKTVSAQVRERLKNQVTEMKAKVPGFRPGLAILQVGDRDDSNLYISMKLKAA
AEIGINANHIKLPNTATEAEVLKCINNLNEDPAIHGFIVQLPLDSNKPINTEKITNAVAP
EKDVDGLSSINAGKLSRGDLSNCFIPCTPKGCMELIRQTGVQVAGKKAVVIGRSKIVGAP
MHDLLLWNHATVTTCHSKTASLADEVSKADILVVAAGKAEMVKGEWIKPGSVVIDCGINH
IPDNTKASGKRVVGDVAYASAKERAAYITPVPGGVGPMTVAMLMQSTVESAQRFLEKYKP
GKWNIHYSLLTPITPVPSDIEVSRSCTPKPIDELAREIGLISDEVELYGQCKAKISLSTL
KRLKDQPDGKYIVVTGITPTPLGEGKSTTAVGLVQALGAHLGQNAFACVRQPSQGPTFGI
KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHEASQSDQALYSRLV
PSVDGIRNFSDVQIRRLQRLHIMKMDPATLTNDEINKFVRLDIDPDSITWQRVLDTNDRF
LRTITIGQSPSEKGYTRTAHFDITVASEIMAVLALTNSLENMRERLGKMVVASSKKGIPI
TTEDLGVSGALAVLMKDAIKPNLMQTLEGNPVFVHAGPFANIAHGNSSVLADRIALKLVG
KDGFVVTEAGFGADIGMEKFFDIKCRYSGLQPHVVVLVATIRALKMHGGGPTVMAGVPLP
KEYIVENIPLLEKGCSNLRKQIENARIFGVPVVVAVNAFKSDTEAELQLVIRLAKEAGAF
DAVKCTHWADGGKGAVALAEAVQRASQVPSHFQFLYDVELPVVEKIRIIAQKIYGANDIE
LLPEAELKIIQYTKQGFGNLPICMAKTHLSLSHDPEQKGVPTGFILPIRDVRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDPVTGEVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atgccttccgcggagatcatcagtgggaaaaccgtttcagcccaagtaagggagcgactg
aaaaaccaagttacagaaatgaaagcaaaagttcctggtttcaggccgggccttgctatt
ctgcaggttggtgaccgggatgattcaaatctctacattagcatgaagctgaaggctgcc
gctgagatcggaatcaatgctaatcacatcaagctgccaaacactgctacagaagctgag
gtgctcaaatgcattaacaatttgaatgaagatcctgccatccatgggtttatagtgcaa
ttgcctctggattcaaacaagcccatcaacacagagaaaataaccaatgctgtggcacct
gagaaagacgtcgatggcttgagcagtattaatgcagggaagctgtcacggggtgacctc
agcaactgcttcattccttgcacacccaaaggatgcatggaacttatccggcaaacaggt
gttcaagtagcaggcaaaaaagcagtagtgattggacgcagtaagatcgttggggctcca
atgcatgacctgctgctttggaaccatgcaactgtgaccacttgccattccaagactgca
tcgctggctgacgaagtcagtaaagcagatatcttggtggttgcagctggcaaagctgag
atggtgaaaggtgaatggataaaaccaggttcagtagtgatcgactgtggaatcaatcac
attccagataacacaaaggccagtgggaaaagagttgttggagatgttgcttatgcttca
gcaaaggagagagcagcctatatcacccctgtgcccggtggggttggaccaatgacagtt
gcaatgctgatgcagagtacagtagaaagtgctcaacgttttcttgagaagtacaaacct
ggcaagtggaatattcattatagcctgctcactcctataactcctgttccaagcgacatc
gaagtttcacggtcatgtactcctaagcccattgatgagctggccagagaaattggcctg
atttcagacgaagtagagttgtatggtcaatgcaaagccaaaatctcactgtcaacactg
aaacgactcaaagatcaaccagatggaaaatacattgtagtaacaggcataactcccaca
ccactgggggaagggaagagtactacagccgtagggctggttcaagctttgggtgcgcac
cttggtcagaatgcctttgcatgtgttcgtcaaccttctcaagggccgacttttggaatt
aaaggtggggcagctggaggtggctattctcaggttattcctatggaagagtttaatctc
catctcacgggtgacatccatgctattactgctgccaataacctggttgctgctgctatt
gatgcccgcatcttccatgaggcgtcacagtctgatcaggcactctattcacggttggtt
ccttcagttgacggtattaggaatttctctgatgttcagattcggagactacagagatta
catattatgaaaatggacccagcaactttgacaaatgatgaaataaacaaatttgtgaga
ttggatatcgatccagatagcataacatggcaacgagtactggatacaaatgataggttt
ctgcgaaccattacaattgggcagtctccatctgagaagggatacacacgcacagcccat
tttgacattacagtagctagtgagatcatggcagttttagcactcacaaacagcctggag
aatatgagagaacgcctgggcaaaatggtggtcgcctccagcaagaaaggaattccaatc
accacagaagatctgggagtgagtggtgccctggcagttttgatgaaagatgctattaag
cccaatctcatgcagactttggaaggtaatccagtgtttgtccatgctggtccatttgct
aacatcgctcatggcaactcatctgtcctggcagacagaattgccctgaagcttgttggc
aaggatgggtttgttgtgactgaagctggcttcggagctgatattggcatggaaaaattc
tttgacatcaaatgtcggtattccggtttgcagcctcatgtggtagtcttggttgccacc
atacgagctctgaaaatgcatggtggaggacctacagttatggctggagtccccttgccc
aaagaatacattgtggagaatattccactgttggagaaaggttgcagtaacctgcgcaag
caaattgaaaatgccagaatttttggtgttccagtagtggtggcagtcaatgcattcaaa
tcagatacagaggcagaactacagctggtcatccggttggctaaggaagctggtgctttt
gatgctgtcaaatgcacccactgggctgatgggggtaaaggagctgtggcattagcagaa
gcagtgcagagggcatcacaggtcccaagccatttccagttcttgtatgatgtggaactt
cccgttgtagagaagatcagaattattgcacagaagatctatggggcaaatgacattgaa
ctgctgccagaagctgagctgaaaattattcaatataccaaacagggatttggaaacctg
cccatctgcatggctaaaacccatttgtcattgtctcatgacccagagcagaaaggcgtg
cccactggattcattttacctataagagatgtccgagccagcgtgggtgcaggattcctt
tatcccttagtaggaacaatgagcacaatgccaggacttcctaccaggccttgtttctat
gacattgatctggatcctgtgactggagaagtaaatggactgttctaa

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