U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120305320, updated on 21-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MTHFD1
Gene description
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MTHFD1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024096466.1 (854670..912694, complement)

NW_024096466.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 25 Neighboring gene A-kinase anchoring protein 5 Neighboring gene uncharacterized LOC120305388 Neighboring gene phosphofructokinase, platelet

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_024096466 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables formate-tetrahydrofolate ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
C-1-tetrahydrofolate synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024096466.1 Reference ASM1654583v1

    Range
    854670..912694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039336997.1 → XP_039192931.1  C-1-tetrahydrofolate synthase, cytoplasmic

    Conserved Domains (2) summary
    PLN02759
    Location:307 → 935
    PLN02759; Formate--tetrahydrofolate ligase
    COG0190
    Location:6 → 294
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.