KEGG   ENZYME: 1.3.1.70
Entry
EC 1.3.1.70                 Enzyme                                 
Name
Delta14-sterol reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ Delta14-oxidoreductase
Reaction(IUBMB)
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ [RN:R05639]
Reaction(KEGG)
R05639;
(other) R07483
Substrate
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol [CPD:C05108];
NADP+ [CPD:C00006]
Product
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol [CPD:C11455];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This enzyme acts on a range of steroids with a 14(15)-double bond.
History
EC 1.3.1.70 created 2001
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00222  Delta14-sterol reductase
K19532  Delta14-sterol reductase (lamin-B receptor)
Genes
HSA3930(LBR) 7108(TM7SF2)
PTR451314(TM7SF2) 457776(LBR)
PPS100973026(TM7SF2) 100994490(LBR)
GGO101125385(LBR) 101135476(TM7SF2)
PON100174610(LBR) 100436442(TM7SF2)
PPYG129007129(TM7SF2) 129028519(LBR)
NLE100582089(TM7SF2) 100594061(LBR)
HMH116457362(LBR) 116468986(TM7SF2)
SSYN129458096(LBR) 129467093(TM7SF2)
MCC700801(LBR) 721985(TM7SF2)
MCF101865138(TM7SF2) 102133452(LBR)
MTHB126935579 126937128
MNI105469557(TM7SF2) 105478369(LBR)
CSAB103231006(LBR) 103231049(TM7SF2)
CATY105576946(LBR) 105577458(TM7SF2)
PANU101015302(LBR) 101026856(TM7SF2)
TGE112606313(TM7SF2) 112625952(LBR)
MLEU105549134(TM7SF2) 105552325(LBR)
RRO104662828(TM7SF2) 104668573(LBR)
RBB108538748(LBR) 108543165(TM7SF2)
TFN117076126(LBR) 117081206(TM7SF2)
PTEH111522385(TM7SF2) 111537085(LBR)
CANG105512175(TM7SF2) 105516699(LBR)
CJC100410497(TM7SF2) 100415074(LBR)
SBQ101030744(LBR) 101032782(TM7SF2)
CIMI108302721(LBR) 108310253(TM7SF2)
ANAN105722314(LBR) 105724441(TM7SF2)
CSYR103260395(TM7SF2) 103275075(LBR)
MMUR105863815(LBR) 105878505(TM7SF2)
LCAT123627516(LBR) 123641388(TM7SF2)
PCOQ105810144(LBR) 105827342(TM7SF2)
OGA100943017(LBR) 100948660(TM7SF2)
MMU73166(Tm7sf2) 98386(Lbr)
MCAL110285268(Tm7sf2) 110300132(Lbr)
MPAH110320815(Tm7sf2) 110321481(Lbr)
RNO293688(Tm7sf2) 89789(Lbr)
MCOC116067924(Lbr) 116103434(Tm7sf2)
ANU117710835(Tm7sf2) 117721844(Lbr)
MUN110546667(Lbr) 110549316(Tm7sf2)
CGE100766362(Tm7sf2) 100770668(Lbr)
MAUA101824117(Tm7sf2) 101831332(Lbr)
PROB127223712(Lbr) 127228743(Tm7sf2)
PLEU114682079(Tm7sf2) 114684425(Lbr) 114685641
MORG121435914(Lbr) 121454158(Tm7sf2)
MFOT126498409 126502191
AAMP119817642(Tm7sf2) 119827749(Lbr)
NGI103724971(Tm7sf2) 103726259(Lbr)
HGL101698844(Lbr) 101699579(Tm7sf2)
CPOC100721369(Lbr) 100725462(Tm7sf2)
CCAN109687161(Tm7sf2) 109695262(Lbr) 109703101
DORD105989197(Tm7sf2) 106001119(Lbr)
DSP122102742(Lbr) 122104892(Tm7sf2)
PLOP125359715(Lbr) 125361293(Tm7sf2)
NCAR124958778 124962173
MMMA107136004(Tm7sf2) 107140504(Lbr)
OCU100345014 100354153
OPI101518604(LBR) 101534263(TM7SF2)
TUP102479981(TM7SF2) 102499087(LBR)
GVR103586688(LBR) 103596369(TM7SF2)
CFA476027(TM7SF2) 490391(LBR)
CLUD112648830(LBR) 112659246(TM7SF2)
VVP112923567(LBR) 112924279(TM7SF2)
VLG121496000(LBR) 121501778(TM7SF2)
NPO129500676(TM7SF2) 129508861(LBR)
AML100469158(TM7SF2) 100470463(LBR)
UMR103669083(LBR) 103679569(TM7SF2)
UAH113244131(TM7SF2) 113262908(LBR)
UAR123778309(TM7SF2) 123791860(LBR)
ELK111149659 111150734
LLV125078164 125085971
MPUF101681647(LBR) 101693076(TM7SF2)
MNP132019115(TM7SF2) 132025525(LBR)
MLK131814580(LBR) 131815136(TM7SF2)
NVS122913093(TM7SF2) 122918692(LBR)
ORO101363278(TM7SF2) 101367798(LBR)
EJU114215496(LBR) 114220193(TM7SF2)
ZCA113914972(TM7SF2) 113932995(LBR)
MLX118013006(LBR) 118016031(TM7SF2)
NSU110571361(LBR) 110576355(TM7SF2)
LWW102739673 102741192(TM7SF2)
FCA101083545(TM7SF2) 101085014(LBR)
PYU121015010(LBR) 121023713(TM7SF2)
PCOO112851927(TM7SF2) 112863170(LBR)
PBG122476159(LBR) 122483997(TM7SF2)
PVIV125159601(LBR) 125176094(TM7SF2)
LRUF124504863 124510311
PTG102948976(LBR) 102955166(TM7SF2)
PPAD109246985(TM7SF2) 109250738(LBR)
PUC125925856 125930942
AJU106968615 106971150
HHV120234125(LBR) 120240119(TM7SF2)
BTA282384(TM7SF2) 509348(LBR)
BOM102268365(LBR) 102284498(TM7SF2)
BIU109554379(TM7SF2) 109570576(LBR)
BBUB102404836(LBR) 102408746(TM7SF2)
BBIS104987215(TM7SF2) 104997884(LBR)
CHX100861120(TM7SF2) 102187420(LBR)
OAS100037702(TM7SF2) 101110348(LBR)
BTAX128061458(LBR) 128068866(TM7SF2)
CSUM138082843(TM7SF2) 138090360(LBR)
ODA120874662(TM7SF2) 120880355(LBR)
CCAD122430613(TM7SF2) 122452149(LBR)
MREE136168275(LBR) 136169715(TM7SF2)
MBEZ129548788(TM7SF2) 129551642(LBR)
SSC100514510(TM7SF2) 110255643(LBR)
CFR102518423(TM7SF2) 102520379(LBR)
CBAI105070669(TM7SF2) 105083938(LBR)
CDK105099770(LBR) 105102615(TM7SF2)
VPC102525851(TM7SF2) 102528823(LBR)
BACU103005659(LBR) 103018459(TM7SF2)
BMUS118898871(TM7SF2) 118904119(LBR)
LVE103070851(TM7SF2) 103074870(LBR)
OOR101285570(TM7SF2) 101288815(LBR)
DLE111177515(LBR) 111183772(TM7SF2)
PCAD102974913(TM7SF2) 102981747(LBR)
PSIU116752901(LBR) 116758810(TM7SF2)
NASI112402173(TM7SF2) 112404958(LBR)
ECB100056588(TM7SF2) 100056997(LBR)
EPZ103556266(LBR) 103559145(TM7SF2)
EAI106833598(TM7SF2) 106844724(LBR)
MYB102261657(TM7SF2) 102263102(LBR)
MYD102768045(LBR) 102774135(TM7SF2)
MMYO118665325(TM7SF2) 118678774(LBR)
MLF102422536(TM7SF2) 102424598(LBR)
MDT132222376(LBR) 132241435(TM7SF2)
PKL118714939(TM7SF2) 118727708(LBR)
EFUS103293450(LBR) 103302072(TM7SF2)
MNA107533642(TM7SF2) 107543637(LBR)
DRO112317164(TM7SF2) 112318856(LBR)
SHON118991710(TM7SF2) 119003171(LBR)
AJM119044438(LBR) 119050288(TM7SF2)
PDIC114499728(TM7SF2) 114512414(LBR)
PHAS123829439(TM7SF2) 123833114(LBR)
MMF118627975(TM7SF2) 118640495(LBR)
PPAM129068588(TM7SF2) 129073002(LBR)
HAI109384274(TM7SF2) 109391472(LBR)
RFQ117018607(LBR) 117030209(TM7SF2)
PALE102884834(LBR) 102892754(TM7SF2)
PGIG120584869(TM7SF2) 120619133(LBR)
PVP105292614(LBR) 105297878(TM7SF2)
RAY107497503(TM7SF2) 107521069(LBR)
MJV108396387(TM7SF2) 108403503(LBR)
TOD119244572(LBR) 119249992(TM7SF2)
SARA101536833(LBR) 101556294(TM7SF2)
SETR126013392(LBR) 126018036(TM7SF2)
LAV100663931(TM7SF2) 100674330(LBR)
TMU101343201 101353559
ETF101651543(LBR) 101663249(TM7SF2)
DNM101428711(LBR) 101443517(TM7SF2)
MDO100019067(LBR) 100030557(TM7SF2)
GAS123247840(LBR) 123251494(TM7SF2)
SHR100924570(LBR) 100935000(TM7SF2)
AFZ127540941 127559534
PCW110195322(TM7SF2) 110205526(LBR) 110208733
TVP118847777(LBR) 118853522(TM7SF2)
PBRV138141751(LBR) 138144835(TM7SF2)
OAA100076190(LBR) 114810169(TM7SF2)
GGA396285(TM7SF2)
PCOC116230962(LBR)
MGP100547254(LBR)
CJO107311040(LBR)
TPAI128078318(LBR)
LMUT125690023(LBR)
NMEL110396037(LBR)
APLA101800362(LBR)
ACYG106031541(LBR)
CATA118253633(LBR)
AFUL116487634(LBR)
TGU100221936(LBR)
LSR110477501(LBR) 116184685
SCAN103819284(LBR)
PMOA120496543 120505974(LBR)
OTC121346926(LBR)
PRUF121357043(LBR)
GFR102041926(LBR)
FAB101807754(LBR)
OMA130251390(LBR)
PHI102105655(TM7SF2) 102109830(LBR)
PMAJ107202231(LBR)
CCAE111926261(LBR)
CCW104685563(LBR)
CBRC103612691(LBR)
ACOE138100376 138107708(LBR)
ETL114073700(LBR)
ZAB102072016(LBR)
ZLE135446054(LBR) 135460288(TM7SF2)
ACHL103805830(LBR)
SVG106853922(LBR)
MMEA130583043(LBR) 130587143
HRT120747804(TM7SF2) 120750579(LBR)
SATI136359554(LBR) 136374815(TM7SF2)
FPG101915288(LBR)
FCH102060143(LBR)
CCRI104159825(LBR)
NNT104399273
SHAB115613612(LBR)
ACUN113478163(LBR)
TALA104357415(LBR)
ACHC115350139(LBR)
HALD104311166(LBR)
HLE104838139(LBR)
AGEN126052675
HHAR128149895(LBR)
GCL127014953
CSTI104557513(LBR)
LDI104349836(LBR)
MNB103771789(LBR)
DPUB104300894(LBR)
PPUS135186665(LBR)
AVIT104273012(LBR)
BRHI104500354(LBR)
EGZ104134581(LBR)
NNI104019277(LBR)
PCRI104023809(LBR)
PCAO104044077(LBR)
PADL103925018(LBR)
AFOR103894455(LBR)
FGA104075313(LBR)
GSTE104256491(LBR)
CLV102088345(LBR)
MUI104541373(LBR)
PGUU104457557(LBR)
PLET104613644(LBR)
EHS104510345
CMAC104487691(LBR)
CUCA104067035(LBR)
TEO104369668(LBR)
BREG104629188(LBR)
OHA104331966(LBR)
ACAR104521803(LBR)
CPEA104386204(LBR)
CVF104294657(LBR)
RTD128906937(LBR)
AAM106482709(LBR)
AROW112963403(LBR)
NPD112942773(LBR)
TGT104578957(LBR)
DNE112980048(LBR)
SCAM104151590(LBR)
ASN102370446(LBR) 102376249(TM7SF2)
AMJ102560387(TM7SF2)
CPOO109319772(LBR)
PSS102454363(LBR) 102456010
CMY102935118(LBR) 102941821(TM7SF2)
CCAY125633686(LBR) 125640312(TM7SF2)
DCC119853166(LBR) 119858898(TM7SF2)
CPIC101937424(LBR) 101938344(TM7SF2)
TST117874505(LBR) 117880777(TM7SF2)
CABI116832688(LBR) 116838856(TM7SF2)
MRV120368979(TM7SF2) 120400986(LBR)
ACS100553093(tm7sf2) 100555974(lbr)
ASAO132761376(LBR) 132764024(TM7SF2)
PVT110069861(TM7SF2) 110075397(LBR)
SUND121915388(TM7SF2) 121934749(LBR)
PBI103062155(LBR) 103064553(TM7SF2)
PMUR107295998(TM7SF2) 107297430(LBR)
CTIG120307222(LBR) 120314938(TM7SF2)
TSR106548912(LBR) 106550138(TM7SF2)
PGUT117657685(TM7SF2) 117671758(LBR)
APRI131186861(TM7SF2) 131189354(LBR)
PTEX113433231(LBR) 113447491(TM7SF2)
NSS113421674(LBR) 113423843(TM7SF2)
VKO123021794(TM7SF2) 123025291(LBR)
PMUA114586536(TM7SF2) 114594621(LBR)
PRAF128403761(TM7SF2) 128411070(LBR)
ZVI118076487(TM7SF2) 118083216(LBR)
HCG128337492(TM7SF2) 128350113(LBR)
GJA107106332(LBR) 107110095(TM7SF2)
STOW125437412(LBR) 125442594(TM7SF2)
EMC129329955(LBR) 129337401(TM7SF2)
XLA108716485(lbr.L) 378609(lbr.S) 379527(tm7sf2.L)
XTR100127815(tm7sf2) 100145693(lbr)
NPR108785256(TM7SF2) 108787063(LBR)
RTEM120917331(TM7SF2) 120937858(LBR)
BBUF120980529(TM7SF2) 120999603(LBR)
BGAR122920337(TM7SF2) 122933816(LBR)
MUO115465308(LBR) 115480595(TM7SF2)
GSH117356893(LBR) 117364583(TM7SF2)
DRE368360(lbr) 494054(tm7sf2)
SRX107720613 107732420 107732539
SANH107690042 107693941 107698344 107701161
SGH107548864 107553478 107555157 107601526
CCAR109080244 109097963 109097984 109109386
CAUA113054335 113063105 113076135 113120709
CGIB127938434 127984246 128021157
PTET122325500(lbr) 122352673(tm7sf2)
LROH127171816(tm7sf2) 127183291(lbr)
OMC131527501(lbr) 131548418(tm7sf2)
PPRM120476457(tm7sf2) 120493906(lbr)
RKG130082795(tm7sf2) 130103072(lbr)
MAMB125260960(tm7sf2) 125278270(lbr)
CIDE127502536 127520413
CERY137019098(lbr) 137029660(tm7sf2)
MASI127410185 127415709 127432886
TROS130546030(tm7sf2) 130565790(lbr)
TDW130412246(tm7sf2) 130434846(lbr)
MANU129430174(lbr) 129446913(tm7sf2)
IPU108258129 108276901
IFU128600906(lbr) 128620609(tm7sf2)
PHYP113525525(tm7sf2) 113546867(lbr)
SMEO124377407(lbr) 124393938(tm7sf2)
TFD113647144(lbr) 113650239(tm7sf2)
TVC132843517(lbr) 132863156(tm7sf2)
TRN134319945(lbr) 134332393(tm7sf2)
AMEX103027772(tm7sf2) 103032852(lbr)
CMAO118815284(lbr) 118824488(tm7sf2)
EEE113576086(tm7sf2) 113585135(lbr)
CHAR105892807(lbr) 105909175(tm7sf2)
TRU101069224(tm7sf2) 101077221(lbr) 115252790
TFS130515654(lbr) 130537562(tm7sf2)
TNGGSTEN00006711G001 GSTEN00020397G001
LCO104918313(lbr) 104926328(tm7sf2)
NCC104949272 104954428 104954430(tm7sf2)
TBEN117489080(lbr) 117499612(tm7sf2)
CGOB115003506(lbr) 115018666(tm7sf2)
PGEO117440017(lbr) 117458705(tm7sf2)
GACU117536587(lbr) 117552883(tm7sf2)
EMAC134872405(tm7sf2) 134876956(lbr)
ELY117263652(tm7sf2) 117270923(lbr)
EFO125897155(lbr) 125898859(tm7sf2)
PLEP121952673(tm7sf2) 121955683(lbr)
SLUC116058121(tm7sf2) 116065556(lbr)
ECRA117955074(tm7sf2) 117961645(lbr)
ESP116699962(tm7sf2) 116705883(lbr)
PFLV114566946(tm7sf2) 114573571(lbr)
GAT120807821(lbr) 120823091(tm7sf2)
PPUG119194865(lbr) 119215243(tm7sf2)
AFB129106958(lbr) 129113690(tm7sf2)
CLUM117727008(lbr) 117743072(tm7sf2)
PSWI130202365(lbr) 130213366(tm7sf2)
CANA137786046(lbr) 137802823(tm7sf2)
CVE137871137(lbr) 137886870(tm7sf2)
MSAM119895395(tm7sf2) 119908875(lbr)
SCHU122862600(lbr) 122888151(tm7sf2)
CUD121518932(tm7sf2) 121521616(lbr)
ALAT119012471(lbr) 119031244(tm7sf2)
ASTR137606375(tm7sf2) 137613177(lbr)
MZE101467007(tm7sf2) 101487127(lbr)
ONL100701576(lbr) 100706037(tm7sf2)
OAU116314226(lbr) 116323214(tm7sf2)
OLA101159885(lbr) 101162861(tm7sf2)
OML112140975(lbr) 112141526(tm7sf2)
CSAI133460335(tm7sf2)
XMA102216750(tm7sf2) 102237315(lbr)
XCO114152694(tm7sf2) 114158766(lbr)
XHE116727879(tm7sf2) 116734371(lbr)
PRET103458037(lbr) 103476010(tm7sf2)
PFOR103133891(tm7sf2)
PLAI106963454(tm7sf2)
PMEI106922601(tm7sf2)
GAF122824818(lbr) 122844345(tm7sf2)
PPRL129368663(tm7sf2) 129369177(lbr)
CVG107091379(tm7sf2) 107093275(lbr)
CTUL119778740(lbr) 119788061(tm7sf2)
GMU124876840(tm7sf2) 124882493(lbr)
NFU107386671(tm7sf2) 107396011(lbr)
KMR108233817(tm7sf2) 108246513(lbr)
ALIM106523126(tm7sf2) 106532953
NWH119418728(lbr) 119420090(tm7sf2)
AOCE111572615(tm7sf2) 111583488(lbr)
EJA138196639(tm7sf2) 138205649(lbr)
MCEP124998672(lbr) 125021274(tm7sf2)
CSEM103380676(lbr) 103394887(tm7sf2)
POV109628461(tm7sf2) 109632449(lbr)
SSEN122780235(tm7sf2) 122784281(lbr)
HHIP117758001(lbr) 117774046(tm7sf2)
HSP118099152(lbr) 118121762(tm7sf2)
PPLT128456950(tm7sf2) 128460018(lbr)
SMAU118289802(lbr) 118301076(tm7sf2)
LCF108894070 108901765
SDU111216371(lbr) 111222365(tm7sf2)
SLAL111661334(lbr) 111663879(tm7sf2)
XGL120788738(lbr) 120802147(tm7sf2)
HCQ109508767(tm7sf2) 109524925(lbr)
SSCV125982573(tm7sf2) 125990178(lbr)
SBIA133491922(tm7sf2) 133496382(lbr)
PEE133415816(tm7sf2) 133416641(lbr)
PTAO133467644(tm7sf2) 133468418(lbr)
BPEC110165111(tm7sf2) 110175403(lbr)
MALB109960420(tm7sf2) 109968075
BSPL114849607(lbr) 114869655(tm7sf2)
SJO128371603(tm7sf2) 128377228(lbr)
SASA106571452 106603135(tm7sf2) 106607865
STRU115154689 115174736 115192120
OTW112217644 112228827 112250363(lbr)
OMY110522282 110529660(lbr) 110533998(tm7sf2)
OGO123990803(lbr) 123995138 124007611
ONE115107809 115135622(tm7sf2) 115139361
OKI109866178 109873196(tm7sf2) 109900791
OKE118385101 118386957 118390378 118398607(lbr)
SALP111951202(tm7sf2) 111954352 111964196 111972907
SNH120019008 120024390(lbr) 120057250
CCLU121541853 121548865 121552282(lbr) 121579498
ELS105010932(tm7sf2) 105017775(lbr)
SFM108920219(tm7sf2) 108925158(lbr)
PKI111835145(tm7sf2) 111854033(lbr)
AANG118230081(lbr) 118235564(tm7sf2)
LOC102683290(lbr)
PSPA121310134(tm7sf2) 121317139(lbr)
ARUT117398619 117411599(lbr) 117969682
PSEX120526124(lbr) 120539345(tm7sf2)
LCM102358779(LBR) 102367079(TM7SF2)
CMK103181605(lbr)
CPLA122543862(tm7sf2) 122548562(lbr)
HOC132830341(lbr) 132836343(tm7sf2)
LERI129697587(lbr)
PMRN116939578 116943268 116947160(TM7SF2) 116947945
LRJ133341173 133342329 133347208 133347373 133359394 133359844
BFO118414075
BBEL109488145
CIN100186956
SCLV120336709
SPU581447
LPIC129265148
APLC110974280 110974347
ARUN117300592 117305232
AJC117106656
SKO100374928 100376417
DMEDmel_CG17952(LBR)
DER6548282
DSE6615434
DSIDsimw501_GD11624(Dsim_GD11624)
DYADyak_GE12220
DAN6496109
DSR110177664
DPO4805241
DPE6592725
DMN108159763 117192342
DWI6641057
DGR116805138
DMODmoj_GI18730
DAZ108616736
DNV115564635
DHE111601217
DVI6626881
CCAT101448446
BOD106626845
BDR105223860
RZE108354984 108359437
AOQ129244920
TDA119680477
MDE101894280
SCAC106081247
LCQ111680371
LSQ119610663
GFS119636766
ECOE129940487
AGA1271476
ACOZ120950594
AARA120894444
AMER121589515 121601754
ASTE118502793
AFUN125766090
AMOU128310097
AAG5569649
AALB109401131 109422686
ASUA134214582 134223404
CQUCpipJ_CPIJ012350
CPII120414389
CNS116340683
BCOO119071893
LLL129797270
PPAP129799137
AME724925
ACER107996541
ALAB122714677
ADR102679323
AFLR100866578
BIM100740181
BBIF117205025
BVK117230919
BVAN117154009
BHUN126871716
BTER100647654
BAFF126921855
BPYO122567852
BPAS132913031
FVI122527487
CCAL108623685
OBB114877281
OLG117602779
MGEN117219277
NMEA116423900
CGIG122400619
SOC105203958
MPHA105836173
AEC105145390
ACEP105618114
PBAR105433257
VEM105566629
HST105186748
DQU106749681
CFO105255938
FEX115234980
LHU105667694(LBR)
PGC109864098
OBO105286153
PCF106793381
PFUC122524755
VPS122630956
VCRB124426035
VVE124951593
NVI100123600
CSOL105367341
TPRE106648081
LHT122508032
LBD127280202
MDL103577613
CGLO123268143
FAS105267809
DAM107043765
AGIF122851414
VCAN122412844
CCIN107275143
TCA103312575 103312760 103312761 103315078
SOY115879795
AGRG126747623
ATD109596614
CSET123314816 123314925 123318759
AGB108903317
LDC111510418
DVV114335732
NVL108559533
APLN108738396
PPYR116162785 116173325
OTU111429073
BMOR101737517
BMAN114249061
MSEX115440829
DPLKGM_212278
BANY112048099
MJU123870350
NIQ126772330
VCD124543789
MCIX123658453
PMAC106708695
PPOT106100037
PXU106122247
BPHI137933686
PRAP110992619
ZCE119834027
LSIN126975201
AAGE121733492
HAW110372473
HZE124633881
TNL113505366
SLIU111357362
OFU114360484
ATRA106137510
GMW113509765
PXY105389055
PGW126371462
LGLY125229777
CSTB134744566
CCRN123301668
API100159503
DNX107169292
AGS114122208
RMD113552184
ACOO126842911
DVT126901980
BTAB109039355
CLEC106666353
HHAL106685424
NLU111059087
HVI124361201
MQU128992624
PHUPhum_PHUM517050
FOC113213994
ZNE110831842
CSEC111872740
BROR134541583
IEL124157872
DMK116928574
AFRA136030547
PVM113822972
PJA122255462
PCHN125032554
PMOO119596603
HAME121865670
PCLA123770467
CQD128698567
PTRU123501226
ESN127005243
MNZ135195045
MRJ136831330
HAZT108668053
EAF111710111
LSM121122417 121123599
TCF131889881
PPOI119093117 119094370
DSV119458001
RSAN119375116
RMP119167224
VDE111244448
VJA111264972
CSCU111620173
CVS136977579
PTEP107454179
ABRU129983839
UDV129224031
SDM118201880
LPOL106461073 106461568 111089939
PMEO129583528
HROHELRODRAFT_187232
LGILOTGIDRAFT_118629
PVUL126821244
PCAN112562689
BGT106065041
GAE121371501 121371502 121371503
HRF124111959
HRJ124285962
HASI137293597
CRG105317853 105341250
CANU128155388
CVN111123895 111128051
OED125649088 130051729
MYI110442449 110442461 110454663
PMAX117321823 117321824 117323876
AIRR138319251 138321772
MCAF127698659
MMER123534372 123540808 128559279
RPHI132720075 132723559 132728295
DPOL127837550 127873422
MAEA128209699
OBI106880238 106880897
OSN115217064 115217706
LJP135466523
LAK106157959 106157960 106169637
SMMSmp_124300
SHXMS3_00002182
EGLEGR_06785
LLON135485215
NVE5502522
EPA110252825 110252829
ATEN116292115
ADF107327637 107357912
AMIL114956738
MCAZ138025974 138026722
PDAM113672787
SPIS111327469
DGT114532513
XEN124441960
HMG101234437
HSY130657323 130657325
RES135684553
TADTRIADDRAFT_32223 TRIADDRAFT_32264
AQU100640520
ATHAT3G52940(FK)
ALY9313962
CRB17886814
CSAT104711853 104781147 104791553
EUSEUTSA_v10010464mg
BRP103850274 103872154
BNA106389140 106425486 106452434 111206750
BOE106298354 106339961
RSZ108849686 130506150
THJ104805104
CPAP110819749
CIT102613973
CICCICLE_v10012005mg
PVY116127287
MINC123209767
TCC18598152
GRA105786363
GHI107905357 107942121
GAB108463838
HSYR120145829 120154919 120192840
DZI111294913 111310992 111315050
EGR104438487 104443743
GMX100805994
GSJ114380725
PVU137830295
VRA106769598
VAR108326294
VUN114191993
VUM124845537
CCAJ109795498
APRC113872806
MTR25483897
TPRA123902709 123904252
CAM101512523
PSAT127091138
VVO131601696
LJA130718773
ADU107476225 107485200
AIP107617826 107626417 107639617
AHF112728879 112743799 112758972 112775977 112797142
LANG109336634
PCIN129292484
QSAO6P43_009516
FVE101306832
AANS126797780
RCN112195389
PPER18766276 18771694
PMUM103335538 103339736
PAVI110753540 110756336
PDUL117635908
MDM103449393 103453991
MSYL126593502 126600161
PXB103942763 103944306 103955169
ZJU107432135
MNT112091679
CSAV115711443
CSV101207322
CMO103486569
BHJ120090521
MCHA111014345
CMAX111481674 111498711
CMOS111441342 111451551
CPEP111789828 111800900
RCU8288379
MEAN126679213
JCU105636595
HBR110663703
MESC110621907
POP18100073
PEU105121788
PALZ118048205
PNZ133689608
JRE108984792
CILL122277310
CAVE132161948
QSU112039685
QLO115952837
TWL119998471 120011675
VVI100247778
VRI117920881
SLY100750253(HYD2)
SPEN107031601
SOT102595277
SSTN125870473
SDUL129882094
CANN107843191
LBB132629912
NTA107776645 107792080
NSY104215944
NTO104105479
NAU109229729
INI109149432
ITR116030227
SIND105174121
OEU111412755
EGT105960475
SSPL121747986 121764569
SMIL130997928 130997938 131026301 131026302
SHIS125218818
APAN127252140
HAN110924754
ECAD122583934
LSV111893804
CCAV112521995
DCR108218804
CSIN114281293 114299254
RVL131318392
AEW130760333
BVG104898491
SOE110794300
CQI110709402 110729390
ATRI130827352
MOF131168441
NNU104612501
MING122061758
TSS122641996
PSOM113298785 113307626
OSA9268311 9270556
OBR102714404
OGL127780161 127783584
BDI100825049
ATS109760121
TDC119293312 119349675
TAES100270656 123069393 123183233
TUA125530536
LPER127299065
LRD124649409
SBI8059782
ZMA100281352
MFLO136541736
SITA101752761
SVS117846046
PVIR120659991 120671076
PHAI112882588
PDA103696660
EGU105035969 105037491
MUS135608092
ZOF121993042 121997034
DCT110112609
PEQ110033192
AOF109827785 109831723
MSIN131224703 131225067 131234349
ACAK137955788
NCOL116263708
ATR18441424
CJF131035230
SMOSELMODRAFT_449548(FK-2) SELMODRAFT_449602(FK-1)
PPP112293662
APROF751_2894
OLUOSTLU_49215
MISMICPUN_107831
MPPMICPUCDRAFT_31205
GSLGasu_18960
CCPCHC_T00003466001
SCEYNL280C(ERG24)
SEUBDI49_4470
SPAOSPAR_N00520
AGOAGOS_AFR346W
ERCEcym_3597
KLAKLLA0_C12265g
KMXKLMA_80276(ERG24)
LTHKLTH0C09306g
ZROZYRO0B06754g
CGR2889143(GVI51_I02717)
NCSNCAS_0I02580(NCAS0I02580)
NDINDAI_0A07170(NDAI0A07170)
TPFTPHA_0P01120(TPHA0P01120)
TBLTBLA_0B08330(TBLA0B08330)
TGBHG536_0D05040
TDLTDEL_0D05430(TDEL0D05430)
KAFKAFR_0A08190(KAFR0A08190)
KNGKNAG_0K02230(KNAG0K02230)
ZMKHG535_0H03450
SLUDSCDLUD_002574
DHADEHA2C15752g
PICPICST_36016
PGUPGUG_02536 PGUG_04548
SPAASPAPADRAFT_60137
LELPVL30_003356(ERG24)
LBG92208927(LODBEIA_P37310)
CALCAALFM_C209400CA(ERG24)
CTPCTRG_01869
COTCORT_0C05300
CDUCD36_23520
CTEN90981761(ERG24)
CLUCLUG_03122
CLUSA9F13_12g01540
CAURCJI96_0000856
PPAPAS_chr1-1_0411
PKZC5L36_0B04700
BNNFOA43_003302
OPAHPODL_00839
YLI2906662(YALI2_C00612g)
NCRNCU08762(erg-3)
NTENEUTE1DRAFT64261(NEUTE1DRAFT_64261)
SMP10802626(SMAC4_04520)
PANPODANSg4732
PBELQC761_703210(ERG24)
PPSDQC762_703210(ERG24)
PPSPQC763_703210(ERG24)
PPSAQC764_703210(ERG24)
TTTTHITE_155704
MTMMYCTH_50083
CTHRCTHT_0022090
MGRMGG_13986
PPEIPpBr36_10782
PGRIPgNI_00156
TMNUCRPA7_1292
SSCKSPSK_01119
FGRFGSG_02346 FGSG_06606
FPUFPSE_01648 FPSE_03777
FPOAFPOAC1_002455 FPOAC1_010314
FVNFVRRES_02742 FVRRES_11302
FVRFVEG_05520 FVEG_09413
FOXFOXG_02348 FOXG_10757
NHENECHADRAFT_100268 NECHADRAFT_94706
FFCNCS54_00606600 NCS54_00814600 NCS54_00866200
FKRNCS57_00644700 NCS57_00908200
FMUJ7337_002256 J7337_005009
TRETRIREDRAFT_121733 TRIREDRAFT_81049
TRRM419DRAFT_141503 M419DRAFT_99422
TATV25775907(TrAtP1_005065) 25780008(TrAtP1_004991)
TASP36607152(DELTA(14)STEROL) 36618792(TrAFT101_004462)
MAW19252604(J3458_014509) 19252839(J3458_006963)
MAJMAA_00310 MAA_06099
MBRN26238324(ERG24) 26243184(erg-3)
PCHMVFPPC_02207 VFPPC_05414
CMTCCM_02751 CCM_03387
AMUSLMH87_002210 LMH87_008941
PLJ28883736(PLICBS_000327) 28888069(PLICBS_003281)
PTKZJDV02_000559(ERG24_1) JDV02_003286(ERG24_2)
VALVDBG_02555
VDAVDAG_09749
CFJCFIO01_01112 CFIO01_11237
CLUPCLUP02_04618 CLUP02_11187
CHIGCH63R_03458 CH63R_08596
CDET87938295(CDEST_01792) 87949779(CDEST_13279) 87951769(CDEST_15269)
SAPOSAPIO_CDS5871
ELAUCREL1_2551
PFYPFICI_10199 PFICI_12011
SSLSS1G_07099
BFUBCIN_10g05280
MBEMBM_02146
PSCOLY89DRAFT_681617
GLZGLAREA_07589
ANIANIA_04094
AFMAFUA_1G03150 AFUA_1G05720
ACTACLA_028880 ACLA_053310
NFINFIA_019020 NFIA_055040 NFIA_098900
AORAO090009000362 AO090023000728
ANGAn01g07000 An18g03480
AFVAFLA_007071 AFLA_010994
ALUCAKAW2_20777A AKAW2_31244S(ERG24)
ACHEACHE_10917S(ERG24) ACHE_80507A(ERG3_2)
APUUAPUU_22173S APUU_40244S(ERG24)
PCSN7525_000786 N7525_006318 N7525_009587
PDPPDIP_73720
POUPOX_e06779
TMFEYB26_000911
TRGTRUGW13939_03742
CIMCIMG_02517 CIMG_03894
CPW9693907(ERG24_2) 9696734(ERG24_1)
UREUREG_05336
ABEARB_00813 ARB_05648
TVETRV_00674 TRV_01214
PBLPAAG_01795
PBNPADG_00480
BGHBDBG_05014
PNOSNOG_01654
PTEPTT_11361
PTRR6341795(PtrM4_097650)
BZECOCCADRAFT_835
BSCCOCSADRAFT_203750
BORCOCMIDRAFT_10201
AALTCC77DRAFT_259954
ARABEKO05_0008809
ZTRMYCGRDRAFT_109241(ERG24)
PFJMYCFIDRAFT_26731(ERG4)
FFUCLAFUR5_01573
CBETCB0940_01327
BCOMBAUCODRAFT_62052
NPAUCRNP2_481 UCRNP2_4939
TMLGSTUM_00005658001
SPO2540113(erg24)
SOMSOMG_03919(erg24)
CNECNA01070
CNBCNBA1040
CNGCNAG_00117
CGICGB_B1300C
CDEUCNBG_0438
CDEP91087539(L203_103328)
KMG30160529(I203_104337)
KNE92178741(IAR55_001482)
TMSTREMEDRAFT_41207
TASAA1Q1_01752 A1Q1_06312
CCACCcaHIS019_0205030(ERG24)
TVSTRAVEDRAFT_147688
DSQDICSQDRAFT_179308
PCOPHACADRAFT_265128
SHSSTEHIDRAFT_79891
HIRHETIRDRAFT_318728
FMEFOMMEDRAFT_154311
GTRGLOTRDRAFT_62003
RSXRhiXN_08842
LBCLACBIDRAFT_295646
CCICC1G_05509 CC1G_10937
ABPAGABI1DRAFT114207(AGABI1DRAFT_114207)
ABVAGABI2DRAFT191223(AGABI2DRAFT_191223)
PCUBJR316_0006032 JR316_0006041
MPRMPER_02838 MPER_08494
MRRMoror_10029 Moror_14303 Moror_3831
MOREE1B28_007613 E1B28_011197
SCMSCHCO_02643127(SCHCODRAFT_02643127)
CPUTCONPUDRAFT_146424
SLASERLADRAFT_477485
WSEWALSEDRAFT_52480
WICJ056_000377
UMAUMAG_11962
PFPPFL1_01226
SGRAEX895_001079
MGLMGL_3750
MRTMRET_1717
MSYMMSY001_0080
PGRPGTG_13421
PTRCPtA15_6A318
PSTRPst134EA_003092
MLRMELLADRAFT_114812
RIEOCT59_014625
MBRMONBRDRAFT_38824
DDIDDB_G0267448 DDB_G0284407(erg24)
DPPDICPUDRAFT_147138
TETTTHERM_00394500
PTMGSPATT00000886001
PTIPHATRDRAFT_48260
TPSTHAPSDRAFT_2186
AAFAURANDRAFT_59212
TBRTb11.01.7170
TBGTbgDal_XI17430
TCR507129.30 507969.60
LMALMJF_32_2320
LIFLINJ_32_2470
LDOLDBPK_322470
LMILMXM_31_2320
LMAT92511994(LSCM1_01884)
LBZLBRM_32_2550
LPANLPMP_322450
LOI92358871(LSCM4_02917)
LEIS94178698(GH5_03208)
LENR94169634(CUR178_02364)
LEIN94186123(JIQ42_02403)
PHET94288696(JKF63_02594)
NGRNAEGRDRAFT_73130
EHXEMIHUDRAFT_439583
 » show all
Reference
1  [PMID:32908]
  Authors
Bottema CK, Parks LW.
  Title
Delta14-sterol reductase in Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 531:301-7 (1978)
DOI:10.1016/0005-2760(78)90212-6
Reference
2  [PMID:6444198]
  Authors
Paik YK, Trzaskos JM, Shafiee A, Gaylor JL
  Title
Microsomal enzymes of cholesterol biosynthesis from lanosterol. Characterization, solubilization, and partial purification of NADPH-dependent delta 8,14-steroid 14-reductase.
  Journal
J Biol Chem 259:13413-23 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.70
IUBMB Enzyme Nomenclature: 1.3.1.70
ExPASy - ENZYME nomenclature database: 1.3.1.70
BRENDA, the Enzyme Database: 1.3.1.70
CAS: 69403-07-2

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