United supporters have craved meaningful success on the pitch since the retirement of the legendary Sir Alex Ferguson in 2013 - and they appear to have a new hero.
The Portuguese manager was serenaded by the Stretford End faithful with chants of "Amorim's red army" as he made his way off the pitch and he remains unbeaten in his opening three games, with this thrashing providing early signs of what may lie ahead under his command.
Previous club Sporting had won all 22 home games under Amorim since the start of last season and he began his league tenure at the Theatre of Dreams in similar manner.
Kobbie Mainoo returned from an injury lay-off and gave Everton an early warning with a shot that was straight at Jordan Pickford in the third minute, but United struggled to imposed themselves before netting the opening goal.
Rashford's form suffered under the now-departed Erik Ten Hag but he showed signs of his capabilities by taking his tally to four league goals for the season with strikes in each half, albeit the first coming via a deflection off Branthwaite.
The much-maligned Zirkzee has been written off by some of the fanbase but was given a start ahead of Rasmus Hojlund and repaid his manager's faith with two goals - the first from Fernandes' pass into an open net and the second after fine work by the sprightly Diallo.
The Ivorian was given few chances by Ten Hag but demonstrated why he may be a valuable player under the new regime, showcasing his workrate by hassling and harrying the Everton backline throughout the game, and he has now provided three assists in two games from the right wing-back role.
United move up to ninth place in a packed December and after a fine start Amorim's credentials will be severely put to the test when his side travel to title-chasing Arsenal on Wednesday.