Zhao et al., 2014 - Google Patents

Beneficial synergistic effects of microdose lithium with pyrroloquinoline quinone in an Alzheimer's disease mouse model

Zhao et al., 2014

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Document ID
7684858038207866877
Author
Zhao L
Gong N
Liu M
Pan X
Sang S
Sun X
Yu Z
Fang Q
Zhao N
Fei G
Jin L
Zhong C
Xu T
Publication year
Publication venue
Neurobiology of aging

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Alzheimer's disease (AD) is a complicated, neurodegenerative disorder involving multifactorial pathogeneses and still lacks effective clinical treatment. Recent studies show that lithium exerts disease-modifying effects against AD. However, the intolerant side effects …
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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