Ouattara et al., 2009 - Google Patents

Implication of NMDA receptors in the antidyskinetic activity of cabergoline, CI-1041, and Ro 61-8048 in MPTP monkeys with levodopa-induced dyskinesias

Ouattara et al., 2009

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Document ID
7675291042036602261
Author
Ouattara B
Belkhir S
Morissette M
Dridi M
Samadi P
Grégoire L
Meltzer L
Di Paolo T
Publication year
Publication venue
Journal of molecular neuroscience

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This study assessed striatal N-methyl-D-aspartate (NMDA) glutamate receptors of 1-methyl 4- phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) monkeys with levodopa (L-DOPA)-induced dyskinesias (LID). In a first experiment, four MPTP monkeys receiving L-DOPA/Benserazide …
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl group being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
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    • A61K31/404—Indoles, e.g. pindolol
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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