Gaffney et al., 2012 - Google Patents

One‐flask synthesis of cyclic diguanosine monophosphate (c‐di‐GMP)

Gaffney et al., 2012

View HTML
Document ID
6592588614629967504
Author
Gaffney B
Jones R
Publication year
Publication venue
Current Protocols in Nucleic Acid Chemistry

External Links

Snippet

The bacterial signaling molecule, cyclic diguanosine monophosphate (c‐di‐GMP), plays a key role in controlling biofilm formation and pathogenic virulence, among many other functions. It has widespread consequences for human health, and current research is …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

Similar Documents

Publication Publication Date Title
Zhao et al. Cascade copper-catalyzed 1, 2, 3-trifunctionalization of terminal allenes
Lee et al. A Simple and General Platform for Generating Stereochemically Complex Polyene Frameworks by Iterative Cross‐Coupling
Gaffney et al. One‐flask synthesis of cyclic diguanosine monophosphate (c‐di‐GMP)
Clarke et al. Polymorphism in multiple component crystals: Forms III and IV of gallic acid monohydrate
Dell'Isola et al. Synthesis and Antiviral Properties of Spirocyclic [1, 2, 3]‐Triazolooxazine Nucleosides
Ren et al. Synthesis of Difluoromethyl Pyrazolines and Pyrazoles by [3+ 2] Cycloaddition Reaction of Difluoroacetohydrazonoyl Bromides with Electron‐deficient Olefins
Bertho et al. β-C (sp 2)–H alkylation of enamides using xanthate chemistry
Gaffney et al. One‐Flask Synthesis of Cyclic Diguanosine Monophosphate (c‐di‐GMP)
Moehlig et al. Cytosine derivatives form hemiprotonated dimers in solution and the gas phase
CN110845466A (en) Oxacyclononadiene derivative, pharmaceutical composition thereof, preparation method and application thereof
Herrera-Arizmendi et al. Effect of New Analogs of Hexyloxy Phenyl Imidazoline on Quorum Sensing in Chromobacterium violaceum and In Silico Analysis of Ligand‐Receptor Interactions
Guttormsen et al. Total synthesis of phorbazole B
D'Errico et al. Synthesis of 5‐Aminoimidazole‐4‐Carboxamide Riboside (AICAR) and Its Derivatives Using Inosine as Starting Material
Derdau et al. Synthesis and analysis of isotopically stable labeled nitrosamines as mass spectrometry standards for drug impurity quality control
CN103724357A (en) Synthetic method of 3, 4-dihydropyran [3, 2-b] indole-2-ketones compound
Gaffney et al. Synthesis of Biotinylated c-di-GMP and c-di-AMP using Click Conjugation
Santschi et al. Delineating the physical organic profile of the 6-fluoro glycosyl donor
Chiba et al. Synthesis of Nonnatural Oligonucleotides Made Exclusively of Alkynyl C‐Nucleosides with Nonnatural Bases
Chrominski et al. Efficient synthesis of trifluoromethylated purine ribonucleosides and ribonucleotides
Agnihotri et al. Synthesis of a di-and a trisaccharide related to the O-antigen of Escherichia coli O83: K24: H31
Hou et al. Preparation of DNA and RNA Fragments Containing Guanine N2‐Thioalkyl Tethers
Lartia et al. Preparation of azido containing oligonucleotides through diazo transfer reaction
Sarac et al. Solid‐phase synthesis of DNA and RNA 5′‐O‐triphosphates using cycloSal chemistry
Ohgi et al. Chemical synthesis of oligoribonucleotides with 2′‐O‐(2‐cyanoethoxymethyl)‐protected phosphoramidites
Heckel Nucleobase‐Caged Phosphoramidites for Oligonucleotide Synthesis