Ji et al., 2018 - Google Patents

Identification of susceptibility pathways for the role of chromosome 15q25. 1 in modifying lung cancer risk

Ji et al., 2018

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Document ID
6514384991640367808
Author
Ji X
Bossé Y
Landi M
Gui J
Xiao X
Qian D
Joubert P
Lamontagne M
Li Y
Gorlov I
de Biasi M
Han Y
Gorlova O
Hung R
Wu X
McKay J
Zong X
Carreras-Torres R
Christiani D
Caporaso N
Johansson M
Liu G
Bojesen S
Le Marchand L
Albanes D
Bickeböller H
Aldrich M
Bush W
Tardon A
Rennert G
Chen C
Teare M
Field J
Kiemeney L
Lazarus P
Haugen A
Lam S
Schabath M
Andrew A
Shen H
Hong Y
Yuan J
Bertazzi P
Pesatori A
Ye Y
Diao N
Su L
Zhang R
Brhane Y
Leighl N
Johansen J
Mellemgaard A
Saliba W
Haiman C
Wilkens L
Fernandez-Somoano A
Fernandez-Tardon G
van der Heijden E
Kim J
Dai J
Hu Z
Davies M
Marcus M
Brunnström H
Manjer J
Melander O
Muller D
Overvad K
Trichopoulou A
Tumino R
Doherty J
Goodman G
Cox A
Taylor F
Woll P
Brüske I
Manz J
Muley T
Risch A
Rosenberger A
Grankvist K
Johansson M
Shepherd F
Tsao M
Arnold S
Haura E
Bolca C
Holcatova I
Janout V
Kontic M
Lissowska J
Mukeria A
Ognjanovic S
Orlowski T
Scelo G
Swiatkowska B
Zaridze D
Bakke P
Skaug V
Zienolddiny S
Duell E
Butler L
Koh W
Gao Y
Houlston R
McLaughlin J
Stevens V
Nickle D
Obeidat M
Timens W
Zhu B
Song L
Artigas M
Tobin M
Wain L
Gu F
Byun J
Kamal A
Zhu D
Tyndale R
Wei W
Chanock S
Brennan P
Amos C
Publication year
Publication venue
Nature Communications

External Links

Snippet

Genome-wide association studies (GWAS) identified the chromosome 15q25. 1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25. 1 affects lung cancer risk, have not …
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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Hybridisation probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/18—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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