Coutinho et al., 1999 - Google Patents
A role for spinal nitric oxide in mediating visceral hyperalgesia in the ratCoutinho et al., 1999
View HTML- Document ID
- 4340981078991254497
- Author
- Coutinho S
- Gebhart G
- Publication year
- Publication venue
- Gastroenterology
External Links
Snippet
Background & Aims: Intracolonic instillation of zymosan in rats produces hyperalgesia (ie, facilitates the visceromotor response to colorectal distention) mediated by activity at spinal N- methyl-D-aspartate (NMDA) and non-NMDA receptors. Nitric oxide (NO·) production often …
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitric oxide 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O=[N] 0 title abstract description 85
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- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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