Kanamori et al., 2013 - Google Patents

Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway

Kanamori et al., 2013

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Document ID
3199154501490905298
Author
Kanamori H
Takemura G
Goto K
Tsujimoto A
Ogino A
Takeyama T
Kawaguchi T
Watanabe T
Morishita K
Kawasaki M
Mikami A
Fujiwara T
Fujiwara H
Seishima M
Minatoguchi S
Publication year
Publication venue
The American journal of pathology

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We investigated the effect of resveratrol, a popular natural polyphenolic compound with antioxidant and proautophagic actions, on postinfarction heart failure. Myocardial infarction was induced in mice by left coronary artery ligation. Four weeks postinfarction, when heart …
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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