Wang et al., 2015 - Google Patents

The inhibitory effect of the hepatitis B virus singly-spliced RNA-encoded p21. 5 protein on HBV nucleocapsid formation

Wang et al., 2015

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Document ID
2498014716516080058
Author
Wang Y
Liou G
Lin C
Chen M
Kuo T
Tsai K
Huang C
Chen Y
Huang L
Chou Y
Chang C
Publication year
Publication venue
PLoS One

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Hepatitis B virus (HBV) is the smallest DNA virus and the major cause of acute and chronic hepatitis. The 3.2 kb HBV viral genome generates four major species of unspliced viral transcript as well as several alternatively spliced RNAs. A 2.2 kb singly-spliced RNA is the …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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