Li et al., 2021 - Google Patents

Quercetin attenuates trauma-induced heterotopic ossification by tuning immune cell infiltration and related inflammatory insult

Li et al., 2021

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Document ID
2076001847114060108
Author
Li J
Sun Z
Luo G
Wang S
Cui H
Yao Z
Xiong H
He Y
Qian Y
Fan C
Publication year
Publication venue
Frontiers in Immunology

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Heterotopic ossification (HO) is one of the most intractable disorders following musculoskeletal injury and is characterized by the ectopic presence of bone tissue in the soft tissue leading to severe loss of function in the extremities. Recent studies have indicated …
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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