Mandarano et al., 2010 - Google Patents

Development and use of iron oxide nanoparticles (Part 2): The application of iron oxide contrast agents in MRI

Mandarano et al., 2010

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Document ID
1888755264174406586
Author
Mandarano G
Lodhia J
Eu P
Ferris N
Davidson R
Cowell S
Publication year
Publication venue
Biomedical Imaging and Intervention Journal

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Magnetic resonance imaging (MRI) is a medical imaging tool that can incorporate contrast agents to enhance its ability to identify and characterise pathologies. MRI contrast agents can be paramagnetic such as gadolinium, or superparamagnetic such as iron oxide …
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    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
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    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
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    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
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