Buendia Duque et al., 2019 - Google Patents

Combined inhibition of HDAC and EGFR reduces viability and proliferation and enhances STAT3 mRNA expression in glioblastoma cells

Buendia Duque et al., 2019

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Document ID
18329490305184733247
Author
Buendia Duque M
Pinheiro K
Thomaz A
da Silva C
Freire N
Brunetto A
Schwartsmann G
Jaeger M
de Farias C
Roesler R
Publication year
Publication venue
Journal of Molecular Neuroscience

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Abstract Changes in expression of histone deacetylases (HDACs), which epigenetically regulate chromatin structure, and mutations and amplifications of the EGFR gene, which codes for the epidermal growth factor receptor (EGFR), have been reported in glioblastoma …
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