Shi et al., 2019 - Google Patents

In vitro and clinical studies of gene therapy with recombinant human adenovirus-p53 injection for malignant melanoma

Shi et al., 2019

Document ID
18327541065341298540
Author
Shi S
Li B
Dong Y
Ge Y
Qu X
Lu L
Yuan Y
Li L
Li Y
Publication year
Publication venue
Human Gene Therapy Clinical Development

External Links

Snippet

Malignant melanoma is an aggressive tumor with high fatality rates and poor prognosis, mainly due to the lack of efficient treatment methods. The present study investigated the potential antitumor effects of recombinant adenovirus p53 (rAd-p53) on human malignant …
Continue reading at www.liebertpub.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Similar Documents

Publication Publication Date Title
Hartmann et al. HGF/Met signaling in head and neck cancer: impact on the tumor microenvironment
Ceci et al. Targeting tumor-associated macrophages to increase the efficacy of immune checkpoint inhibitors: a glimpse into novel therapeutic approaches for metastatic melanoma
Nguyen et al. Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity
Kreatsoulas et al. Translational landscape of glioblastoma immunotherapy for physicians: guiding clinical practice with basic scientific evidence
JP5504163B2 (en) Cancer diagnosis and treatment methods
Shi et al. In vitro and clinical studies of gene therapy with recombinant human adenovirus-p53 injection for malignant melanoma
EP2364163B1 (en) Composition comprising in vitro expanded t-lymphocytes and vessel formation inhibitors suitable in the treatment of cancer
UA109891C2 (en) COMPOSITION OF TUMOR ASSOCIATED PEPTIDES FOR TREATMENT OF CANCER DISEASES
Zhang et al. Gene delivery of TIPE2 inhibits breast cancer development and metastasis via CD8+ T and NK cell-mediated antitumor responses
JP7104949B2 (en) Nucleotide sequence encoding CAR, ROBO1 CAR-NK cells expressing this CAR, preparation and use thereof
Li et al. Suppression of the expression of hypoxia-inducible factor-1α by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult rats
Christensen et al. A critical role of the PTEN/PDGF signaling network for the regulation of radiosensitivity in adenocarcinoma of the prostate
Li et al. Liposomal co-delivery of PD-L1 siRNA/Anemoside B4 for enhanced combinational immunotherapeutic effect
Dovedi et al. Emerging targeted therapies for bladder cancer: a disease waiting for a drug
US12111318B2 (en) Method for treating cancer based on expression levels of translationally controlled tumor protein (TCTP)
CN110022894A (en) Immunogenic compound for cancer therapy
CN116474095A (en) Application of inhibitor of small G protein RBJ
Qu et al. Dectin3 protects against hepatocellular carcinoma by regulating glycolysis of macrophages
US11679100B2 (en) Methods of enhancing immunity
Lin et al. Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma
Tian et al. TRIM59: a membrane protein expressed on bacillus Calmette-Guerin-activated macrophages that induces apoptosis of fibrosarcoma cells by direct contact
CN114504568A (en) Application of small molecule compound in preparing medicine for inducing immunogenic cell death
Zhu et al. Dendritic Cell Vaccine Loaded with MG‐7 Antigen Induces Cytotoxic T Lymphocyte Responses against Gastric Cancer
Chen et al. SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness
Wei et al. MicroRNA-30a-3p inhibits malignant progression of hepatocellular carcinoma through regulating IGF1.