Sebbar et al., 2016 - Google Patents

Novel 1, 4-benzothiazine derivatives: synthesis, crystal structure, and anti-bacterial properties

Sebbar et al., 2016

View PDF
Document ID
18019344188383001714
Author
Sebbar N
Mekhzoum M
Essassi E
Zerzouf A
Talbaoui A
Bakri Y
Saadi M
Ammari L
Publication year
Publication venue
Research on Chemical Intermediates

External Links

Snippet

In order to develop relatively small molecules as pharmacologically active molecules, novel 1, 4-benzothiazine derivatives with triazole and oxazolidinone were synthesized. In this study, a series of 1, 2, 3-triazolylmethyl-1, 4-benzothiazine derivatives were developed by …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1,4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1,4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System

Similar Documents

Publication Publication Date Title
Sebbar et al. Novel 1, 4-benzothiazine derivatives: synthesis, crystal structure, and anti-bacterial properties
Narsimha et al. Synthesis and antibacterial activity of (1-aryl-1, 2, 3-triazol-4-yl) methyl esters of morpholine-3-carboxylic acid
Swetha et al. Synthesis, characterization and antimicrobial evaluation of ferrocene–oxime ether benzyl 1 H-1, 2, 3-triazole hybrids
Kocabalkanli et al. Synthesis of Mannich Bases of Some 2, 5‐Disubstituted 4‐Thiazolidinones and Evaluation of Their Antimicrobial Activities
El Shehry et al. Design, synthesis and biological evaluation of quinoxaline N-propionic and O-propionic hydrazide derivatives as antibacterial and antifungal agents
Mayekar et al. Synthesis and antimicrobial studies on new substituted 1, 3, 4-oxadiazole derivatives bearing 6-bromonaphthalene moiety
Bansode et al. Synthesis of novel 2-(3′-aryl-sydnon-4′-ylidene)-5′-substituted-[1, 3, 4]-thiadiazolylamines and [1, 3, 4]-thiadiazol-2′-yl-3-oxo-[1, 2, 4]-triazoles as antimicrobial agents
Reddy et al. Synthesis and Antimicrobial Activity of Novel Phosphorus Heterocycles with Exocyclic P–C Link
Ammar et al. Synthesis and characterization of new imidazolidineiminothione and bis-imidazolidineiminothione derivatives as potential antimicrobial agents
Atta-Allah et al. Synthesis and antimicrobial activity evaluation of some novel hydrazone, pyrazolone, chromenone, 2-pyridone and 2-pyrone derivatives
Pundeer et al. Synthesis and evaluation of antibacterial and antifungal activities of new (Z)-3-bromo-4-(1, 3-diaryl-1 H-pyrazol-4-yl) but-3-en-2-ones and 4-(3-methyl-1-phenyl-1 H-pyrazol-5-yl)-1, 3-diaryl-1 H-pyrazoles
Zayane et al. Access to new antimicrobial 4-methylumbelliferone derivatives
Prakash et al. Synthesis and antimicrobial activity of 5-((3-aryl-1-phenyl-1 H-pyrazol-4-yl) methylene) thiazolidine-2, 4-diones
Kishore Kumar et al. Synthesis and Antibacterial Activity of Some {6-[(1 H-1, 2, 3-Triazol-4-yl) methoxy]-3-methylbenzofuran-2-yl}(4-bromophenyl) methanone Derivatives
Santhoshi et al. A facile route for the synthesis 1, 4-disubstituted tetrazolone derivatives and evaluation of their antimicrobial activity
Pandey et al. Polyethylene glycol mediated, one‐pot, three‐component synthetic protocol for novel 3‐[3‐Substituted‐5‐mercapto‐1, 2, 4‐triazol‐4‐yl]‐spiro‐(indan‐1′, 2‐thiazolidin)‐4‐ones as new class of potential antimicrobial and antitubercular agents
Sankar et al. Synthesis, Antibacterial and Anticancer Activity of 1, 2-Substituted 2, 3-Dihydro-1 H-Benzo [4, 5] Imidazo [1, 2-c][1, 3, 2] Diazaphosphol-1-Oxides
Kumar et al. Synthesis and antimicrobial activity of quinoxaline based 1, 2, 3-Triazoles
Geies et al. Synthesis and reactions of some new pyrrolylthieno [2, 3-D] quinoxaline and pyrrolopyrazinothienoquinoxalines
Bratenko et al. Polyfunctional Pyrazoles. 9*. Synthesis of 1-Alkyl (Aryl)-3-[4-(Hydroxymethyl)-1 Н-Pyrazol-3-Yl] UReas
Ma et al. Synthesis and antifungal activities of drimane-amide derivatives from sclareol
Parmar et al. Synthesis, Characterization and Antimicrobial Evaluation of Novel Imidazo [1, 2-a] pyrazine-linked 1, 2, 3-Triazole Derivatives via a Click Chemistry Approach
Maruthesh et al. Synthesis and Characterization of Substituted 5-(2-Chloroquinolin-3-yl)-1, 3, 4-oxadiazole-2-amines: Computational, In Silico ADME, Molecular Docking, and Biological Activities
Ahmad et al. Synthesis and study of some heterocyclic compounds from Schiff base of Pinacolone
Kumar et al. Development of New Molecular Entities as Potent Antifungal Agents: Synthesis of Substituted 1, 2, 3-Triazoles