Chung et al., 2024 - Google Patents

Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs)

Chung et al., 2024

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Document ID
17194031350785784766
Author
Chung M
House J
Akhtari F
Makris K
Langston M
Islam K
Holmes P
Chadeau-Hyam M
Smirnov A
Du X
Thessen A
Cui Y
Zhang K
Manrai A
Motsinger-Reif A
Patel C
Exposomics Consortium Adamu Yau Adebamowo Clement Akhtari Farida Akhtari Farida Argos Maria Arunachalam Saravanan Baumert Brittney Beglarian Emily Berger Kimberly Bhutani Jessie Bisson William Breton Carrie Cai Lu Chao Mu-rong Chatziioannou Anastasia Chrysovalantou Cheng Qiwen Chung Ming Kei Chung Ming Kei Chung Ming Kei Clark Robert Cohen Hubal Elaine Conti David Cooke Marcus Costello Elizabeth Cui Yuxia Dierickx Erin Dolinoy Dana Du Xiuxia Engel Lawrence Gao Peng Gaulke Christopher Giebelhaus Ryland T Goodrich Jesse Grafanaki Katerina Gullapalli Rama Habre Rima Haidari Ariana Harari Homero Hart Jaime He Jingxuan Holmes Philip Hood Darryl B House John Hu Hui Hu Chiung-wen James Peter Jankowska Marta Ji Hong Srimathi Kannan Konstantinou Corina Lai Yunjia Langston Mike Lasalle Janine Leang Amy Liang Donghai Liao Jiawen Luo Jiajun Makris Konstantinos C Manz Katherine Miller Gary Motsinger-Reif Alison Ouidir Marion Page Grier Pan Shudi Parker Graham Paul Kimberly Peluso Alina Penning Trevor Pierce Brandon Prajapati Nirmala Prins Gail Quintana Penelope JE Rajasekar Arcot (raja) Ramesh Aramandla Ruden Douglas Rushing Blake Scholl Elizabeth Schüssler-Fiorenza Rose Sophia Miryam Shah Ruchir Shahriar Mohammad Siwakoti Ram Soares Lissa Soliman Ghada States J Christopher Stingone Jeanette Sturla Irizarry Savannah Sun Yangbo Sundseth Scott Teitelbaum Susan Thessen Anne Tong Ai Phuong Vijayakumar Nisha Walker Ryan Wang Yi Whyte Kathryn Wilson Ander Wu Lang Wu K Lily Yuan Xin/jean Zhang Qiong Zhang Xinyue Zhao Neil Zhu Yeyi
Publication year
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Exposome

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This paper explores the exposome concept and its role in elucidating the interplay between environmental exposures and human health. We introduce two key concepts critical for exposomics research. Firstly, we discuss the joint impact of genetics and environment on …
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Classifications

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    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/18—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
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    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/28—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for programming tools or database systems, e.g. ontologies, heterogeneous data integration, data warehousing or computing architectures
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    • G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
    • G06F19/34—Computer-assisted medical diagnosis or treatment, e.g. computerised prescription or delivery of medication or diets, computerised local control of medical devices, medical expert systems or telemedicine
    • G06F19/345—Medical expert systems, neural networks or other automated diagnosis
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    • G06—COMPUTING; CALCULATING; COUNTING
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    • G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
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    • G06F19/322—Management of patient personal data, e.g. patient records, conversion of records or privacy aspects
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
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    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/24—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for machine learning, data mining or biostatistics, e.g. pattern finding, knowledge discovery, rule extraction, correlation, clustering or classification
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/30—Information retrieval; Database structures therefor; File system structures therefor
    • G06F17/30286—Information retrieval; Database structures therefor; File system structures therefor in structured data stores
    • G—PHYSICS
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    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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    • G06F19/36—Computer-assisted acquisition of medical data, e.g. computerised clinical trials or questionnaires
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06Q—DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
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    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
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