Cassano et al., 2004 - Google Patents

Understanding the transition states of phosphodiester bond cleavage: insights from heavy atom isotope effects

Cassano et al., 2004

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Document ID
16951449520286482346
Author
Cassano A
Anderson V
Harris M
Publication year
Publication venue
Biopolymers: Original Research on Biomolecules

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The nucleotides of DNA and RNA are joined by phosphodiester linkages whose synthesis and hydrolysis are catalyzed by numerous essential enzymes. Two prominent mechanisms have been proposed for RNA and protein enzyme catalyzed cleavage of phosphodiester …
Continue reading at harris.chem.ufl.edu (PDF) (other versions)

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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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