Muñoz-Llancao et al., 2015 - Google Patents
Exchange protein directly activated by cAMP (EPAC) regulates neuronal polarization through Rap1BMuñoz-Llancao et al., 2015
View PDF- Document ID
- 16648611322962393242
- Author
- Muñoz-Llancao P
- Henríquez D
- Wilson C
- Bodaleo F
- Boddeke E
- Lezoualc'h F
- Schmidt M
- González-Billault C
- Publication year
- Publication venue
- Journal of Neuroscience
External Links
Snippet
Acquisition of neuronal polarity is a complex process involving cellular and molecular events. The second messenger cAMP is involved in axonal specification through activation of protein kinase A. However, an alternative cAMP-dependent mechanism involves the …
- 230000001537 neural 0 title abstract description 65
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Muñoz-Llancao et al. | Exchange protein directly activated by cAMP (EPAC) regulates neuronal polarization through Rap1B | |
Goldman et al. | Netrin-1 promotes excitatory synaptogenesis between cortical neurons by initiating synapse assembly | |
Humbert et al. | p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton | |
Wynshaw-Boris et al. | LIS1 and dynein motor function in neuronal migration and development | |
Leemhuis et al. | Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation | |
Chenn et al. | Intrinsic polarity of mammalian neuroepithelial cells | |
Vega et al. | The exocyst complex associates with microtubules to mediate vesicle targeting and neurite outgrowth | |
Farías et al. | Wnt-7a induces presynaptic colocalization of α7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons | |
Das et al. | RalA promotes a direct exocyst–Par6 interaction to regulate polarity in neuronal development | |
Fu et al. | Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons | |
Chernyshova et al. | The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones | |
Dupraz et al. | The TC10–Exo70 complex is essential for membrane expansion and axonal specification in developing neurons | |
Yoshizawa et al. | Involvement of a Rac activator, P-Rex1, in neurotrophin-derived signaling and neuronal migration | |
Goswami et al. | TRPV1 at nerve endings regulates growth cone morphology and movement through cytoskeleton reorganization | |
Choe et al. | Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1 | |
Xiao et al. | Neural cell adhesion molecule modulates dopaminergic signaling and behavior by regulating dopamine D2 receptor internalization | |
Bisbal et al. | Protein kinase d regulates trafficking of dendritic membrane proteins in developing neurons | |
Kizhatil et al. | A new activity of doublecortin in recognition of the phospho-FIGQY tyrosine in the cytoplasmic domain of neurofascin | |
Brot et al. | CRMP5 interacts with tubulin to inhibit neurite outgrowth, thereby modulating the function of CRMP2 | |
de Arce et al. | Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation | |
Weng et al. | Changes in Notch signaling coordinates maintenance and differentiation of the Drosophila larval optic lobe neuroepithelia | |
Wang et al. | Eps15 membrane-binding and-bending activity acts redundantly with Fcho1 during clathrin-mediated endocytosis | |
Marte et al. | Leucine‐rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre‐synaptic sites | |
Lussier et al. | Casein kinase 2 phosphorylates G lu A 1 and regulates its surface expression | |
Montgomery et al. | Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum |