Nobili et al., 2023 - Google Patents

Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive

Nobili et al., 2023

Document ID
15029144150247063814
Author
Nobili A
La Barbera L
Mastrantonio R
Palazzo C
Molinari M
D’Amelio M
Viscomi M
Publication year
Publication venue
Neurobiological and Psychological Aspects of Brain Recovery

External Links

Snippet

Most neurological pathologies that afflict humans are associated with the abnormal accumulation and aggregation of specific proteins into the cytoplasm and with mitochondrial dysfunction. Neuronal health is sustained by the fine regulation of protein synthesis and …
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
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    • A61K31/47Quinolines; Isoquinolines
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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