Woodson et al., 1989 - Google Patents

Reverse self-splicing of the Tetrahymena group I intron: implication for the directionality of splicing and for intron transposition

Woodson et al., 1989

Document ID
13037099280748981981
Author
Woodson S
Cech T
Publication year
Publication venue
Cell

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Snippet

Using short oligoribonucleotides as ligated exon substrates, we show that splicing of the Tetrahymena rRNA group I intron is fully reversible in vitro. Incubation of ligated exon RNA with linear intron produces a molecule in which the splice site sequences of the precursor …
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