Fernando, 2009 - Google Patents
Sleeping Beauty mediated targeting of tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in miceFernando, 2009
- Document ID
- 12738120102632531750
- Author
- Fernando S
- Publication year
External Links
Snippet
Recent advances in cancer research have broaden the knowledge of how solid tumors progress. Once thought of as the product of a single aberrant cell with multiple mutations, tumors are the product of that single cell dividing, and then the new mass interacting with …
- 206010028980 Neoplasm 0 title abstract description 192
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Bai et al. | Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes | |
AU2017308473B2 (en) | Manipulated immunoregulatory element and immunity altered thereby | |
JP2023017834A (en) | Modulation of stimulatory and non-stimulatory myeloid cells | |
Amberger et al. | Latest advances for the sleeping beauty transposon system: 23 years of insomnia but prettier than ever: refinement and recent innovations of the sleeping beauty transposon system enabling novel, nonviral genetic engineering applications | |
KR20190114966A (en) | Engineered natural killer cells and uses thereof | |
BR112021007301A2 (en) | compositions and methods to express factor ix | |
US20160074533A1 (en) | Vector encoding therapeutic polypeptide and safety elements to clear transduced cells | |
JP2022058425A (en) | Artificially manipulated neovascularization regulatory system | |
JP2019528774A (en) | Inducible caspases and methods of use | |
KR102249982B1 (en) | Transposon system, kit containing same, and uses thereof | |
JP2010509223A (en) | Pro-focal targeted gene delivery system for cancer and other diseases | |
AU2018265887B2 (en) | NSG mice lacking MHC class I and class II | |
CN110997902A (en) | SUV39H1 deficient immune cells | |
JP2012501637A (en) | Materials and methods for inhibiting cancer cell invasion associated with FGFR4 | |
CN113498439A (en) | Nano transposon compositions and methods of use | |
EP3359676A1 (en) | Transposon system, kit comprising the same, and uses thereof | |
JP4660486B2 (en) | Anti-cancer therapeutic agent containing human apolipoprotein (a) kringle LK68 or LK8 gene as an active ingredient, and cancer treatment method using the same | |
US20210379088A1 (en) | Cancer regression by inducing a regeneration-like response | |
WO2023196843A2 (en) | Compositions and methods for treating cancer by increasing expression of obscn-as1 long-noncoding rna | |
Fernando | Sleeping Beauty mediated targeting of tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in mice | |
WO2019191681A1 (en) | Methods and materials for treating cancer | |
Mori et al. | A therapeutic cancer vaccine targeting carcinoembryonic antigen in intestinal carcinomas | |
Irla et al. | ZAP-70 restoration in mice by in vivo thymic electroporation | |
Ma et al. | Intramuscular expression of plasmid-encoded FVII-Fc immunoconjugate for tumor immunotherapy by targeting tumoral blood vessels and cells | |
US20090217402A1 (en) | Methods and compositions for modulating the activity of peptidases in macrophage and macrophage-like cells |