Alvarez et al., 2003 - Google Patents

Synergistic antinociceptive effects of ketamine and morphine in the orofacial capsaicin test in the rat

Alvarez et al., 2003

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Document ID
12665451197996866103
Author
Alvarez P
Saavedra G
Hernández A
Paeile C
Pelissier T
Publication year
Publication venue
The Journal of the American Society of Anesthesiologists

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Background The clinical efficacy of the noncompetitive N-methyl-d-aspartate receptor antagonist ketamine for treating orofacial pain has already been reported. Side effects related to psychotomimetic disturbances, however, limit ketamine use as an analgesic …
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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