Safavy et al., 2004 - Google Patents

Site-Specifically Traced Drug Release and Biodistribution of a Paclitaxel− Antibody Conjugate toward Improvement of the Linker Structure1

Safavy et al., 2004

Document ID
11904679613322053975
Author
Safavy A
Georg G
Velde D
Raisch K
Safavy K
Carpenter M
Wang W
Bonner J
Khazaeli M
Buchsbaum D
Publication year
Publication venue
Bioconjugate chemistry

External Links

Snippet

Tumor-directed drug delivery is a promising strategy in cancer treatment, and in this field, monoclonal antibodies constitute an important class of targeting vehicles. A critical issue in the design of targeting conjugates is the timing of the release of the cytotoxic payload, with …
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