Sedlazeck et al., 2018 - Google Patents

Accurate detection of complex structural variations using single-molecule sequencing

Sedlazeck et al., 2018

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Document ID
1152456819041215622
Author
Sedlazeck F
Rescheneder P
Smolka M
Fang H
Nattestad M
Von Haeseler A
Schatz M
Publication year
Publication venue
Nature methods

External Links

Snippet

Structural variations are the greatest source of genetic variation, but they remain poorly understood because of technological limitations. Single-molecule long-read sequencing has the potential to dramatically advance the field, although high error rates are a challenge with …
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    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
    • G—PHYSICS
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