Von der Osten et al., 1989 - Google Patents

Use of a recombinant bacterial fructose-1, 6-diphosphate aldolase in aldol reactions: preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1, 4 …

Von der Osten et al., 1989

Document ID
10589977875892983711
Author
Von der Osten C
Sinskey A
Barbas III C
Pederson R
Wang Y
Wong C
Publication year
Publication venue
Journal of the American Chemical Society

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Snippet

A combined enzymatic aldol condensationand catalytic intramolecular reductive amination has been used in the high-yield asymmetric synthesis of polyhydroxylated alkaloids including 1-deoxynojirimycin, 1-deoxymannojirimycin, 1, 4-dideoxy-1, 4-imino-D-arabinitol …
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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