ZA875043B - 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments - Google Patents

7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments

Info

Publication number
ZA875043B
ZA875043B ZA875043A ZA875043A ZA875043B ZA 875043 B ZA875043 B ZA 875043B ZA 875043 A ZA875043 A ZA 875043A ZA 875043 A ZA875043 A ZA 875043A ZA 875043 B ZA875043 B ZA 875043B
Authority
ZA
South Africa
Prior art keywords
aminoacyloxypolyoxylabdanes
acyloxy
medicaments
preparation
Prior art date
Application number
ZA875043A
Inventor
Yatendra Khandelwal
Khandelwal Yatendra
Ramanujam Rajgopalan
Rajgopalan Ramanujam
Alihussein Nomanbha Dohadwalla
Nomanbhai Dohadwall Alihussein
Richard Helmut Rupp
Helmut Rupp Richard
Noel John De Souza
John De Souza Noel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA875043B publication Critical patent/ZA875043B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
ZA875043A 1986-07-11 1987-07-10 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments ZA875043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863623300 DE3623300A1 (en) 1986-07-11 1986-07-11 7-ACYLOXY-6-AMINOACYLOXYPOLYOXYLABDANE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
ZA875043B true ZA875043B (en) 1988-03-30

Family

ID=6304882

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA875043A ZA875043B (en) 1986-07-11 1987-07-10 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments

Country Status (10)

Country Link
EP (1) EP0252482A3 (en)
JP (1) JPS6323878A (en)
KR (1) KR880001642A (en)
AU (1) AU7553887A (en)
DE (1) DE3623300A1 (en)
DK (1) DK354687A (en)
HU (1) HU203229B (en)
IL (1) IL83152A0 (en)
PT (1) PT85302B (en)
ZA (1) ZA875043B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
US4851397A (en) * 1985-03-01 1989-07-25 Hoechst-Roussel Pharmaceuticals Inc. Labdanes, pharmaceutical compositions, and their use
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
JPS6310783A (en) * 1985-11-15 1988-01-18 Nippon Kayaku Co Ltd Novel forskolin derivative
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
CA1307530C (en) * 1986-12-29 1992-09-15 Hoechst-Roussel Pharmaceuticals Inc. Carbamoyloxylabdanes, intermediates and a process for the preparation thereof and their use as medicaments
IN166900B (en) * 1987-06-03 1990-08-04 Hoechst India
JP2504934B2 (en) * 1987-06-29 1996-06-05 日本化薬株式会社 1,6,7-Triacylforskolin derivative
JPH0684367B2 (en) * 1987-06-29 1994-10-26 日本化薬株式会社 New method for producing forskolin derivative
DE3737353A1 (en) * 1987-11-04 1989-05-18 Hoechst Ag NEW ACYLLABDANE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
KR0173317B1 (en) * 1990-07-24 1999-02-01 이젠브루크 라피체 Process for preparation of 6-(substituted-aminopropionyl)derivatives of forskolin
JP3557095B2 (en) * 1998-04-20 2004-08-25 高砂香料工業株式会社 Melanin production inhibitor
WO2016054237A2 (en) * 2014-10-03 2016-04-07 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Poly (adp-ribose) polymerase 1 inhibitors structurally unrelated to nad

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985003637A1 (en) * 1984-02-24 1985-08-29 Halprin Kenneth M Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
IN163242B (en) * 1985-05-03 1988-08-27 Hoechst India
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives

Also Published As

Publication number Publication date
JPS6323878A (en) 1988-02-01
AU7553887A (en) 1988-01-14
DE3623300A1 (en) 1988-01-21
DK354687D0 (en) 1987-07-09
IL83152A0 (en) 1987-12-31
EP0252482A3 (en) 1988-05-04
EP0252482A2 (en) 1988-01-13
PT85302A (en) 1987-08-01
DK354687A (en) 1988-01-12
HUT46900A (en) 1988-12-28
HU203229B (en) 1991-06-28
KR880001642A (en) 1988-04-25
PT85302B (en) 1990-03-30

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