ZA793967B - New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them - Google Patents

New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them

Info

Publication number
ZA793967B
ZA793967B ZA00793967A ZA793967A ZA793967B ZA 793967 B ZA793967 B ZA 793967B ZA 00793967 A ZA00793967 A ZA 00793967A ZA 793967 A ZA793967 A ZA 793967A ZA 793967 B ZA793967 B ZA 793967B
Authority
ZA
South Africa
Prior art keywords
androst
ene
medicaments
preparing
pharmaceutical compositions
Prior art date
Application number
ZA00793967A
Other languages
English (en)
Inventor
Teutsch Jean Georges
Jean Georges Teutsch
Deraedt Roger
Roger Deraedt
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA793967B publication Critical patent/ZA793967B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00793967A 1978-08-16 1979-08-02 New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them ZA793967B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7823851A FR2433536A1 (fr) 1978-08-16 1978-08-16 Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number Publication Date
ZA793967B true ZA793967B (en) 1980-07-30

Family

ID=9211827

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00793967A ZA793967B (en) 1978-08-16 1979-08-02 New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4232015A (xx)
JP (1) JPS5528982A (xx)
AT (1) AT368520B (xx)
AU (1) AU524232B2 (xx)
BE (1) BE878256A (xx)
CH (1) CH641814A5 (xx)
DE (1) DE2933258A1 (xx)
FR (1) FR2433536A1 (xx)
GB (1) GB2029833B (xx)
HU (1) HU180520B (xx)
IE (1) IE48931B1 (xx)
IT (1) IT1164040B (xx)
NL (1) NL7906214A (xx)
PT (1) PT70060A (xx)
SE (1) SE435186B (xx)
ZA (1) ZA793967B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4424218A (en) 1979-08-17 1984-01-03 Roussel Uclaf Novel 3 α-amino steroids
FR2468617A1 (fr) * 1979-10-26 1981-05-08 Roussel Uclaf Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant
US4383947A (en) * 1981-07-24 1983-05-17 The Upjohn Company Introduction of a fluorine atom
US4488995A (en) * 1984-02-06 1984-12-18 E. R. Squibb & Sons, Inc. Androstene-17β-alkylthiomethyl ethers
US6740646B2 (en) * 2002-01-16 2004-05-25 Biotest Laboratories, Llc Bioavailable prodrugs of androgenic steroids and related method
JP4636847B2 (ja) * 2004-10-13 2011-02-23 株式会社ロッテ 全粒粉からなる小麦粉の加工方法及びその加工方法により得られた加工小麦粉並びにその加工小麦粉を使用した食品

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2740798A (en) * 1953-05-25 1956-04-03 Searle & Co 11 beta-hydroxy-17-ethynyl testosterone and esters thereof
US3010957A (en) * 1958-11-26 1961-11-28 Schering Corp Ethinyl androstadienes
FR1349113A (fr) * 1959-01-28 1964-01-17 Upjohn Co Procédé de fabrication de 6-fluoro-11 oxygéné-17-bêta-hydroxy-17 alpha-alkynyl inférieur-4-androstène-3-ones et leurs dérivés acylés
GB1081494A (en) * 1965-09-14 1967-08-31 British Drug Houses Ltd 17ª‡-(alka-1',3'-diynyl)-steroids
US3793308A (en) * 1972-11-08 1974-02-19 Upjohn Co 4-spiro(cyclopropyl)androstenes and process for their production
SE7801152L (sv) * 1977-02-22 1978-08-23 Roussel Uclaf Sett att framstella 17alfa-acetylen-derivat av androst-4-en

Also Published As

Publication number Publication date
HU180520B (en) 1983-03-28
IE48931B1 (en) 1985-06-26
FR2433536A1 (fr) 1980-03-14
NL7906214A (nl) 1980-02-19
FR2433536B1 (xx) 1981-07-24
CH641814A5 (fr) 1984-03-15
GB2029833A (en) 1980-03-26
AU4995879A (en) 1980-03-06
GB2029833B (en) 1983-04-27
SE7905865L (sv) 1980-02-17
PT70060A (fr) 1979-09-01
DE2933258C2 (xx) 1990-10-25
IT7950049A0 (it) 1979-08-14
SE435186B (sv) 1984-09-10
US4232015A (en) 1980-11-04
AT368520B (de) 1982-10-25
JPS5528982A (en) 1980-02-29
BE878256A (fr) 1980-02-14
IE791578L (en) 1980-02-16
AU524232B2 (en) 1982-09-09
JPS636559B2 (xx) 1988-02-10
DE2933258A1 (de) 1980-02-28
IT1164040B (it) 1987-04-08
ATA553479A (de) 1982-02-15

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