ZA771078B - New halogenated derivatives of the 16a-methyl pregnane series,process for preparing them and pharmaceutical compositions - Google Patents

New halogenated derivatives of the 16a-methyl pregnane series,process for preparing them and pharmaceutical compositions

Info

Publication number
ZA771078B
ZA771078B ZA00771078A ZA771078A ZA771078B ZA 771078 B ZA771078 B ZA 771078B ZA 00771078 A ZA00771078 A ZA 00771078A ZA 771078 A ZA771078 A ZA 771078A ZA 771078 B ZA771078 B ZA 771078B
Authority
ZA
South Africa
Prior art keywords
preparing
pharmaceutical compositions
halogenated derivatives
pregnane series
new halogenated
Prior art date
Application number
ZA00771078A
Inventor
G Costerousse
J Teutsch
R Deraedt
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA771078B publication Critical patent/ZA771078B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00771078A 1976-03-02 1977-02-23 New halogenated derivatives of the 16a-methyl pregnane series,process for preparing them and pharmaceutical compositions ZA771078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7605854A FR2342738A1 (en) 1976-03-02 1976-03-02 NEW HALOGEN DERIVATIVES OF THE 16A-METHYL PREGNANE SERIES

Publications (1)

Publication Number Publication Date
ZA771078B true ZA771078B (en) 1978-04-26

Family

ID=9169832

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00771078A ZA771078B (en) 1976-03-02 1977-02-23 New halogenated derivatives of the 16a-methyl pregnane series,process for preparing them and pharmaceutical compositions

Country Status (16)

Country Link
JP (1) JPS52106855A (en)
AT (1) AT355237B (en)
AU (1) AU509948B2 (en)
BE (1) BE851944A (en)
CA (1) CA1082170A (en)
CH (1) CH619969A5 (en)
DE (1) DE2709078C2 (en)
DK (1) DK156401C (en)
FR (1) FR2342738A1 (en)
GB (1) GB1530975A (en)
IE (1) IE44866B1 (en)
LU (1) LU76867A1 (en)
NL (1) NL7702166A (en)
PT (1) PT66261B (en)
SE (1) SE7702250L (en)
ZA (1) ZA771078B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462443A1 (en) * 1979-07-26 1981-02-13 Roussel Uclaf NEW HALOGENIC DERIVATIVE OF THE 16A-METHYL PREGNANE SERIES, PREPARATION METHOD AND APPLICATION AS MEDICINE
FR2533928A1 (en) * 1982-10-05 1984-04-06 Roussel Uclaf NOVEL DICHLORIC DERIVATIVES OF THE 16A-METHYL PREGNANE SERIES, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS
DE4433374A1 (en) * 1994-09-20 1996-03-21 Hoechst Ag 17-deoxi-corticosteroid-21- / O / -carboxylic acid ester, process for their preparation and medicaments containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB928302A (en) * 1958-06-20 1963-06-12 Scherico Ltd í¸-pregnene compounds
US3049554A (en) * 1959-06-01 1962-08-14 Schering Corp 9, 11-dihalogeno-3, 20-diketopregnanes and processes for their manufacture

Also Published As

Publication number Publication date
JPS52106855A (en) 1977-09-07
NL7702166A (en) 1977-09-06
AU2280877A (en) 1978-09-07
DK156401C (en) 1990-01-08
ATA136577A (en) 1979-07-15
IE44866L (en) 1977-09-02
DE2709078C2 (en) 1986-09-11
PT66261A (en) 1977-04-01
PT66261B (en) 1979-01-17
JPS6150960B2 (en) 1986-11-06
LU76867A1 (en) 1977-09-26
CH619969A5 (en) 1980-10-31
BE851944A (en) 1977-09-01
AU509948B2 (en) 1980-06-05
SE7702250L (en) 1977-09-03
DE2709078A1 (en) 1977-09-08
DK156401B (en) 1989-08-14
FR2342738A1 (en) 1977-09-30
AT355237B (en) 1980-02-25
IE44866B1 (en) 1982-04-21
CA1082170A (en) 1980-07-22
GB1530975A (en) 1978-11-01
FR2342738B1 (en) 1979-10-12
DK88277A (en) 1977-09-03

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