ZA201707998B - Injectable pharmaceutical formulations of lefamulin - Google Patents
Injectable pharmaceutical formulations of lefamulinInfo
- Publication number
- ZA201707998B ZA201707998B ZA2017/07998A ZA201707998A ZA201707998B ZA 201707998 B ZA201707998 B ZA 201707998B ZA 2017/07998 A ZA2017/07998 A ZA 2017/07998A ZA 201707998 A ZA201707998 A ZA 201707998A ZA 201707998 B ZA201707998 B ZA 201707998B
- Authority
- ZA
- South Africa
- Prior art keywords
- lefamulin
- pharmaceutical formulations
- injectable pharmaceutical
- injectable
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562180871P | 2015-06-17 | 2015-06-17 | |
PCT/EP2016/063609 WO2016202788A1 (en) | 2015-06-17 | 2016-06-14 | Injectable pharmaceutical formulations of lefamulin |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA201707998B true ZA201707998B (en) | 2021-04-28 |
Family
ID=56131530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA2017/07998A ZA201707998B (en) | 2015-06-17 | 2017-11-24 | Injectable pharmaceutical formulations of lefamulin |
Country Status (27)
Country | Link |
---|---|
US (1) | US12121582B2 (en) |
EP (1) | EP3310331B1 (en) |
JP (1) | JP6818019B2 (en) |
KR (1) | KR102656841B1 (en) |
CN (1) | CN107810000B (en) |
AU (1) | AU2016278774C1 (en) |
BR (1) | BR112017026904B1 (en) |
CA (1) | CA2989372C (en) |
CY (1) | CY1123722T1 (en) |
DK (1) | DK3310331T3 (en) |
EA (1) | EA033988B1 (en) |
ES (1) | ES2843723T3 (en) |
HK (1) | HK1252534A1 (en) |
HR (1) | HRP20210010T1 (en) |
HU (1) | HUE053024T2 (en) |
IL (1) | IL256115A (en) |
LT (1) | LT3310331T (en) |
MX (1) | MX2017015812A (en) |
PH (1) | PH12017502319A1 (en) |
PL (1) | PL3310331T3 (en) |
PT (1) | PT3310331T (en) |
RS (1) | RS61327B1 (en) |
SI (1) | SI3310331T1 (en) |
TW (1) | TWI718158B (en) |
UA (1) | UA121240C2 (en) |
WO (1) | WO2016202788A1 (en) |
ZA (1) | ZA201707998B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202203907A (en) | 2020-04-17 | 2022-02-01 | 奧地利商納畢瓦治療有限責任公司 | Novel therapeutic use of pleuromutilins |
WO2021209596A1 (en) * | 2020-04-17 | 2021-10-21 | Nabriva Therapeutics GmbH | Therapeutic use of pleuromutilins |
EP4135682A1 (en) | 2020-04-17 | 2023-02-22 | Nabriva Therapeutics GMBH | Therapeutic use of pleuromutilins |
CN117677709A (en) * | 2021-07-19 | 2024-03-08 | Jbs科学有限公司 | Method for separating circulating DNA from urine sample |
WO2023152115A1 (en) | 2022-02-09 | 2023-08-17 | Nabriva Therapeutics GmbH | Lefamulin and its derivatives for use in the treatment of a spiral shaped bacteria |
EP4338732A1 (en) | 2022-09-16 | 2024-03-20 | Nabriva Therapeutics GMBH | Lefamulin and its derivatives for use in the treatment of tularemia |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4130709A (en) | 1977-12-08 | 1978-12-19 | Eli Lilly And Company | Pleuromutilin glycoside derivatives |
BE1003647A5 (en) * | 1989-02-28 | 1992-05-12 | Syntex Inc | PHARMACEUTICAL COMPOSITION FOR ADMINISTRATION PARENTERAL nicardipine. |
DE4023848C2 (en) | 1990-07-27 | 1994-04-21 | Huels Chemische Werke Ag | Process for the preparation of 3-C¶1¶ to C¶6¶-Alkoxycarbonylcyclohexanpropionsäureestern |
FR2772272B1 (en) | 1997-12-16 | 2000-01-14 | Rhone Poulenc Rorer Sa | PHARMACEUTICAL COMPOSITIONS BASED ON DALFOPRISTINE AND QUINUPRISTINE AND THEIR PREPARATION |
US6187746B1 (en) | 1997-12-16 | 2001-02-13 | Rhone-Poulenc Rorer S.A. | Pharmaceutical compositions based on dalfopristine and on quinupristine, and preparation thereof |
MXPA02009816A (en) | 2000-04-04 | 2003-03-27 | Smithkline Beecham Plc | 2-hydroxy-mutilin carbamate derivatives for antibacterial use. |
GB0017031D0 (en) | 2000-07-11 | 2000-08-30 | Biochemie Gmbh | Antimicrobials |
GB0207495D0 (en) | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
GB0209262D0 (en) | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
NZ555982A (en) * | 2004-12-30 | 2011-01-28 | Astex Therapeutics Ltd | Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases |
EP2298733B1 (en) | 2005-06-27 | 2016-05-25 | Nabriva Therapeutics AG | Pleuromutilin derivatives containing a hydroxyamino- or acyloxyaminocycloalkyl group |
GB0515995D0 (en) | 2005-08-03 | 2005-09-07 | Sandoz Ag | Organic compounds |
EP1972618A1 (en) * | 2007-03-20 | 2008-09-24 | Nabriva Therapeutics AG | Pleuromutilin derivatives for the treatment of diseases mediated by microbes |
EP2159220A1 (en) * | 2008-09-02 | 2010-03-03 | Nabriva Therapeutics AG | Organic compounds |
WO2011002776A1 (en) * | 2009-06-29 | 2011-01-06 | Nitric Biotherapeutics, Inc. | Pharmaceutical formulations for iontophoretic delivery of an immunomodulator |
EP2399904A1 (en) | 2010-05-26 | 2011-12-28 | Nabriva Therapeutics AG | Process for the preparation of pleuromutilins |
CN103204787B (en) * | 2012-01-17 | 2014-10-01 | 北京艾百诺科技有限公司 | Mulin acetate comprising substituted squaric acid, and application thereof |
CN103626693B (en) * | 2012-08-28 | 2016-09-14 | 中国科学院上海药物研究所 | One class pleuromutilin derivative, its pharmaceutical composition and synthetic method thereof and purposes |
JP6533780B2 (en) * | 2013-05-28 | 2019-06-19 | モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー | Combination therapy comprising oxazolidinone-quinolones for use in the treatment of bacterial infections |
TWI762573B (en) * | 2017-02-10 | 2022-05-01 | 奧地利商納畢瓦治療有限責任公司 | Purification of pleuromutilin |
-
2016
- 2016-06-14 EP EP16729258.0A patent/EP3310331B1/en active Active
- 2016-06-14 WO PCT/EP2016/063609 patent/WO2016202788A1/en active Application Filing
- 2016-06-14 EA EA201890075A patent/EA033988B1/en unknown
- 2016-06-14 UA UAA201712491A patent/UA121240C2/en unknown
- 2016-06-14 DK DK16729258.0T patent/DK3310331T3/en active
- 2016-06-14 PL PL16729258T patent/PL3310331T3/en unknown
- 2016-06-14 ES ES16729258T patent/ES2843723T3/en active Active
- 2016-06-14 AU AU2016278774A patent/AU2016278774C1/en active Active
- 2016-06-14 JP JP2018517478A patent/JP6818019B2/en active Active
- 2016-06-14 HU HUE16729258A patent/HUE053024T2/en unknown
- 2016-06-14 CN CN201680034551.7A patent/CN107810000B/en active Active
- 2016-06-14 US US15/736,865 patent/US12121582B2/en active Active
- 2016-06-14 RS RS20210014A patent/RS61327B1/en unknown
- 2016-06-14 PT PT167292580T patent/PT3310331T/en unknown
- 2016-06-14 KR KR1020177037107A patent/KR102656841B1/en active IP Right Grant
- 2016-06-14 LT LTEP16729258.0T patent/LT3310331T/en unknown
- 2016-06-14 SI SI201631026T patent/SI3310331T1/en unknown
- 2016-06-14 BR BR112017026904-0A patent/BR112017026904B1/en active IP Right Grant
- 2016-06-14 CA CA2989372A patent/CA2989372C/en active Active
- 2016-06-14 MX MX2017015812A patent/MX2017015812A/en unknown
- 2016-06-15 TW TW105118788A patent/TWI718158B/en active
-
2017
- 2017-11-24 ZA ZA2017/07998A patent/ZA201707998B/en unknown
- 2017-12-05 IL IL256115A patent/IL256115A/en active IP Right Grant
- 2017-12-15 PH PH12017502319A patent/PH12017502319A1/en unknown
-
2018
- 2018-09-14 HK HK18111844.5A patent/HK1252534A1/en unknown
-
2021
- 2021-01-05 HR HRP20210010TT patent/HRP20210010T1/en unknown
- 2021-01-13 CY CY20211100027T patent/CY1123722T1/en unknown
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