WO2009013405A3 - Human male fertility control using spata 16 - Google Patents

Human male fertility control using spata 16 Download PDF

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Publication number
WO2009013405A3
WO2009013405A3 PCT/FR2008/000858 FR2008000858W WO2009013405A3 WO 2009013405 A3 WO2009013405 A3 WO 2009013405A3 FR 2008000858 W FR2008000858 W FR 2008000858W WO 2009013405 A3 WO2009013405 A3 WO 2009013405A3
Authority
WO
WIPO (PCT)
Prior art keywords
spata
human male
male fertility
fertility control
human
Prior art date
Application number
PCT/FR2008/000858
Other languages
French (fr)
Other versions
WO2009013405A2 (en
WO2009013405A8 (en
Inventor
Stephane Viville
Jan A M Kremer
Original Assignee
Centre Nat Rech Scient
Stephane Viville
Jan A M Kremer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Stephane Viville, Jan A M Kremer filed Critical Centre Nat Rech Scient
Publication of WO2009013405A2 publication Critical patent/WO2009013405A2/en
Publication of WO2009013405A8 publication Critical patent/WO2009013405A8/en
Publication of WO2009013405A3 publication Critical patent/WO2009013405A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to human male fertility control. The inventors demonstrates that SPATA 16 is necessary for the formation of the human sperm acrosome and, for this purpose, provide human male contraception means and means for the diagnosis and prognosis of teratospermia and, in particular, a globozoospermia.
PCT/FR2008/000858 2007-06-29 2008-06-19 Human male fertility control using spata 16 WO2009013405A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0704719 2007-06-29
FR0704719A FR2918075A1 (en) 2007-06-29 2007-06-29 CONTROL OF THE FERTILITY OF A HUMAN SEX OF MALE SEX VIA SPATA16

Publications (3)

Publication Number Publication Date
WO2009013405A2 WO2009013405A2 (en) 2009-01-29
WO2009013405A8 WO2009013405A8 (en) 2009-03-19
WO2009013405A3 true WO2009013405A3 (en) 2009-05-14

Family

ID=38968877

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/000858 WO2009013405A2 (en) 2007-06-29 2008-06-19 Human male fertility control using spata 16

Country Status (2)

Country Link
FR (1) FR2918075A1 (en)
WO (1) WO2009013405A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011059974A2 (en) 2009-11-10 2011-05-19 Interdigital Patent Holdings, Inc. Collaborative session control transfer and inter-device transfer in internet protocol multimedia subsystem
FR2952373B1 (en) 2009-11-12 2013-05-17 Univ Grenoble 1 CONTROL OF HUMAN FERTILITY VIA DPY19L2
JP2013521721A (en) 2010-03-04 2013-06-10 インターデイジタル パテント ホールディングス インコーポレイテッド Method and apparatus for identification and transfer in internet protocol multimedia subsystem collaborative sessions
CN107181741B (en) 2010-03-18 2020-11-24 交互数字专利控股公司 Method for replicating media session in SCC AS and SCC AS
CN105085675A (en) * 2014-05-14 2015-11-25 深圳市第二人民医院 Mouse SPATA16 gene polyclonal antibody and preparation method thereof
JP2023528090A (en) * 2020-06-01 2023-07-03 コロナ フィード アディティブス エル．エル．シー． Porcine contraceptive compositions, systems and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102996A1 (en) * 2001-06-19 2002-12-27 The Population Council, Inc. Male contraceptives
CN1869222A (en) * 2005-05-24 2006-11-29 中国医学科学院基础医学研究所 Rat testis high expression gene rDJL taking part in spermatozoon acrosome formation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102996A1 (en) * 2001-06-19 2002-12-27 The Population Council, Inc. Male contraceptives
CN1869222A (en) * 2005-05-24 2006-11-29 中国医学科学院基础医学研究所 Rat testis high expression gene rDJL taking part in spermatozoon acrosome formation

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DAM A H D M ET AL: "Globozoospermia revisited", HUMAN REPRODUCTION UPDATE, vol. 13, no. 1, January 2007 (2007-01-01), pages 63 - 75, XP002519106, ISSN: 1355-4786 *
DAM ANIKA H D M ET AL: "Homozygous mutation in SPATA16 is associated with male infertility in human globozoospermia", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 81, no. 4, October 2007 (2007-10-01), pages 813 - 820, XP002466997, ISSN: 0002-9297 *
DATABASE WPI Week 200727, Derwent World Patents Index; AN 2007-273495, XP002519262 *
DAVIES BEN ET AL: "Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility.", MOLECULAR AND CELLULAR BIOLOGY OCT 2004, vol. 24, no. 19, October 2004 (2004-10-01), pages 8642 - 8648, XP002466996, ISSN: 0270-7306 *
MARTIN SCOTT E ET AL: "Applications of RNA interference in mammalian systems", ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, vol. 8, 3 May 2007 (2007-05-03), pages 81 - 108, XP002467153, ISSN: 1527-8204 *
XU MIN ET AL: "Identification and characterization of a novel human testis-specific Golgi protein, NYD-SP12.", MOLECULAR HUMAN REPRODUCTION, vol. 9, no. 1, January 2003 (2003-01-01), pages 9 - 17, XP002466995, ISSN: 1360-9947 *

Also Published As

Publication number Publication date
FR2918075A1 (en) 2009-01-02
WO2009013405A2 (en) 2009-01-29
WO2009013405A8 (en) 2009-03-19

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