WO2001065262A3 - Reagents and methods useful for detecting diseases of the breast - Google Patents

Reagents and methods useful for detecting diseases of the breast Download PDF

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Publication number
WO2001065262A3
WO2001065262A3 PCT/US2001/006516 US0106516W WO0165262A3 WO 2001065262 A3 WO2001065262 A3 WO 2001065262A3 US 0106516 W US0106516 W US 0106516W WO 0165262 A3 WO0165262 A3 WO 0165262A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast
reagents
methods useful
detecting diseases
diseases
Prior art date
Application number
PCT/US2001/006516
Other languages
French (fr)
Other versions
WO2001065262A2 (en
Inventor
Patricia A Billing-Medel
Maurice Cohen
Tracey L Colpitts
Paula N Friedman
Julian Gordon
Edward N Granados
Steven C Hodges
Michael R Klass
Jon D Kratochvil
Lisa Roberts-Rapp
John C Russell
Steven D Stroupe
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority to CA2399047A priority Critical patent/CA2399047C/en
Priority to JP2001563906A priority patent/JP2004503208A/en
Priority to EP01916303A priority patent/EP1259542A2/en
Publication of WO2001065262A2 publication Critical patent/WO2001065262A2/en
Publication of WO2001065262A3 publication Critical patent/WO2001065262A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Multimeric polypeptides antigens comprising polypeptides designated as BS106 and transcribed from breast tissue is described. These sequences are useful for the detecting, diagnosing, staging, monitoring prognosticating or determining the predisposition of an individual to diseases and conditions of the breast such as breast cancer. Also provided are antibodies which specifically bind to BS106-encoded polypeptide or protein.
PCT/US2001/006516 2000-02-29 2001-02-28 Reagents and methods useful for detecting diseases of the breast WO2001065262A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA2399047A CA2399047C (en) 2000-02-29 2001-02-28 Reagents and methods useful for detecting diseases of the breast
JP2001563906A JP2004503208A (en) 2000-02-29 2001-02-28 Reagents and methods useful for detecting breast disease
EP01916303A EP1259542A2 (en) 2000-02-29 2001-02-28 Reagents and methods useful for detecting diseases of the breast

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51644400A 2000-02-29 2000-02-29
US09/516,444 2000-02-29

Publications (2)

Publication Number Publication Date
WO2001065262A2 WO2001065262A2 (en) 2001-09-07
WO2001065262A3 true WO2001065262A3 (en) 2002-04-11

Family

ID=24055614

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/006516 WO2001065262A2 (en) 2000-02-29 2001-02-28 Reagents and methods useful for detecting diseases of the breast

Country Status (4)

Country Link
EP (1) EP1259542A2 (en)
JP (1) JP2004503208A (en)
CA (1) CA2399047C (en)
WO (1) WO2001065262A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034920B2 (en) 1997-10-31 2011-10-11 Abbott Laboratories Nucleic acid primers and probes for detecting breast cells
AU1777201A (en) * 1999-11-16 2001-05-30 Eos Biotechnology, Inc. Novel methods of diagnosing and determining prognosis of breast cancer, compositions, and methods of screening for breast cancer modulators
WO2006049868A1 (en) * 2004-10-28 2006-05-11 Abbott Laboratories Nucleic acid primers and probes for detecting breast cells
WO2011008746A2 (en) * 2009-07-14 2011-01-20 Temple University Of The Commonwealth System Of Higher Education Serum markers associated with early and other stages of breast cancer
US8980269B2 (en) 2009-07-14 2015-03-17 Temple University Of The Commonwealth System Of Higher Education G-protein coupled receptor-associated sorting protein 1 as a cancer biomarker

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018945A1 (en) * 1996-10-31 1998-05-07 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1998021331A1 (en) * 1996-11-12 1998-05-22 Incyte Pharmaceuticals, Inc. Human breast tumor-specific proteins
WO1999023230A1 (en) * 1997-10-31 1999-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018945A1 (en) * 1996-10-31 1998-05-07 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1998021331A1 (en) * 1996-11-12 1998-05-22 Incyte Pharmaceuticals, Inc. Human breast tumor-specific proteins
WO1999023230A1 (en) * 1997-10-31 1999-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BECKER RM ET AL.: "Identification of Mammaglobin B, a Novel Member of the Uteroglobin Gene Family", GENOMICS, vol. 54, 1998, pages 70 - 78, XP000892829 *

Also Published As

Publication number Publication date
CA2399047C (en) 2011-04-19
WO2001065262A2 (en) 2001-09-07
CA2399047A1 (en) 2001-09-07
JP2004503208A (en) 2004-02-05
EP1259542A2 (en) 2002-11-27

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