WO1998050065A3 - The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein - Google Patents

The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein Download PDF

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Publication number
WO1998050065A3
WO1998050065A3 PCT/EP1998/001951 EP9801951W WO9850065A3 WO 1998050065 A3 WO1998050065 A3 WO 1998050065A3 EP 9801951 W EP9801951 W EP 9801951W WO 9850065 A3 WO9850065 A3 WO 9850065A3
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Prior art keywords
active substances
influencing
administration
controlling
device used
Prior art date
Application number
PCT/EP1998/001951
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German (de)
French (fr)
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WO1998050065A2 (en
Inventor
Marion Sangster Eckmiller
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Marion Sangster Eckmiller
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Publication date
Application filed by Marion Sangster Eckmiller filed Critical Marion Sangster Eckmiller
Priority to AU76417/98A priority Critical patent/AU7641798A/en
Priority to CA002288631A priority patent/CA2288631A1/en
Priority to EP98924097A priority patent/EP0980256A2/en
Publication of WO1998050065A2 publication Critical patent/WO1998050065A2/en
Publication of WO1998050065A3 publication Critical patent/WO1998050065A3/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to the use of an active substance influencing the calcium homeostasis of cells to treat degeneration of sensory cells and adjacent cells.
PCT/EP1998/001951 1997-05-05 1998-04-02 The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein WO1998050065A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU76417/98A AU7641798A (en) 1997-05-05 1998-04-02 The use of biologically active substances for influencing the extracellular areaof sensory cells and method for controlling the administration of active substa nces and device used therein
CA002288631A CA2288631A1 (en) 1997-05-05 1998-04-02 The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein
EP98924097A EP0980256A2 (en) 1997-05-05 1998-04-02 The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1997118826 DE19718826A1 (en) 1997-05-05 1997-05-05 Use of biologically active agents to influence the extracellular space of sensory cells and methods for drug administration control
DE19718826.5 1997-05-05

Publications (2)

Publication Number Publication Date
WO1998050065A2 WO1998050065A2 (en) 1998-11-12
WO1998050065A3 true WO1998050065A3 (en) 1999-06-10

Family

ID=7828596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/001951 WO1998050065A2 (en) 1997-05-05 1998-04-02 The use of biologically active substances for influencing the extracellular area of sensory cells and method for controlling the administration of active substances and device used therein

Country Status (5)

Country Link
EP (1) EP0980256A2 (en)
AU (1) AU7641798A (en)
CA (1) CA2288631A1 (en)
DE (1) DE19718826A1 (en)
WO (1) WO1998050065A2 (en)

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PL343412A1 (en) * 1998-03-05 2001-08-13 Senju Pharma Co Pharmaceutical composition for prophylaxis and therapy of diseases associated with ocular fundus tissue cytopathy
FR2784030B1 (en) 1998-10-02 2002-12-20 Inst Nat Sante Rech Med USE OF CALCIUM AND / OR CGMP-DEPENDENT CHANNEL BLOCKERS FOR THE TREATMENT OF RETINE CONDITIONS
US6864243B1 (en) * 2000-05-12 2005-03-08 Inspire Pharmaceuticals, Inc. Method for treating retinal degeneration with purinergic receptor agonists
JP4758641B2 (en) * 2003-12-12 2011-08-31 千寿製薬株式会社 α-Ketoamide derivative, process for producing the same, and use thereof
KR101055236B1 (en) * 2003-12-12 2011-08-08 센주 세이야꾸 가부시키가이샤 Alpha-ketoamide derivatives, and methods of making and using the same
DE102009056597A1 (en) * 2009-12-02 2011-06-09 Tobias Brockmann Use of flavin derivatives and their salts for preparing a medicament for the treatment of pathologies of the internal limiting membrane (ILM), and the flavin derivative is riboflavin or roseoflavin
EP3484463B1 (en) 2016-08-19 2020-02-12 The United States of America, as Represented by The Secretary, Department of Health and Human Services Office of Technology Transfer Selective estrogen-receptor modulators (serms) confer protection against photoreceptor degeneration
WO2020036658A2 (en) * 2018-04-27 2020-02-20 The Johns Hopkins University Drugs promoting retinal rod photoreceptor survival

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WO1993015608A1 (en) * 1992-02-14 1993-08-19 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors
CN1077092A (en) * 1992-04-10 1993-10-13 张勇 A kind of preparation method of beverage caring for eyes
CN1082896A (en) * 1992-07-18 1994-03-02 苏州第六制药厂 Process for preparing dizzy-stopping suppository
JPH06234645A (en) * 1993-02-09 1994-08-23 Toagosei Chem Ind Co Ltd Vasculatization inhibitor
WO1994025020A1 (en) * 1993-04-28 1994-11-10 Pharmacia Ab Method and means for inhibiting posterior capsule opacification
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JPH07215892A (en) * 1994-01-27 1995-08-15 Sumitomo Pharmaceut Co Ltd Medicinal composition for curing spontaneouse deafness
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WO1998018485A1 (en) * 1996-10-31 1998-05-07 Alcon Laboratories, Inc. The use of calpain inhibitors to treat ocular neural pathology
EP0848952A1 (en) * 1996-12-03 1998-06-24 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of lower alkanoyl l-carnitines to produce a medicament suitable for the therapeutic treatment of retinopathies

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US5252568A (en) * 1992-01-24 1993-10-12 Texas A&M University System Treatment of low pressure glaucoma and ischemic retinal degeneration with loxapine

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SU1297862A1 (en) * 1980-07-03 1987-03-23 Институт цитологии и генетики СО АН СССР Agent for treatment of pigment degeneration of retina
JPS5718609A (en) * 1980-07-08 1982-01-30 Senjiyu Seiyaku Kk Intraocular hypotensor
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JPS57130923A (en) * 1981-02-07 1982-08-13 Eiji Sakata Remedy and preventive for vertigo
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WO1990012590A1 (en) * 1989-04-14 1990-11-01 State Of Oregon, State Board Of Higher Education, Oregon Health Sciences University Treatment of ocular disease by modulation of matrix metalloproteinases and their inhibitor
US5156852A (en) * 1989-04-20 1992-10-20 La Haye Laboratories, Inc. Composition and method for combating macular degeneration
EP0430539A2 (en) * 1989-11-22 1991-06-05 Visionex, Inc. Ocular implants
WO1992007580A1 (en) * 1990-11-05 1992-05-14 Biosource Genetics Corporation Therapeutic uses of melanin
EP0485232A1 (en) * 1990-11-08 1992-05-13 Unitika Ltd. Neovascularisation inhibitors
JPH04182432A (en) * 1990-11-19 1992-06-30 Toshio Tanaka Calcium-dependent cyclic nucleotide phosphodiesterase inhibitor
WO1993015608A1 (en) * 1992-02-14 1993-08-19 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors
CN1077092A (en) * 1992-04-10 1993-10-13 张勇 A kind of preparation method of beverage caring for eyes
CN1082896A (en) * 1992-07-18 1994-03-02 苏州第六制药厂 Process for preparing dizzy-stopping suppository
JPH06234645A (en) * 1993-02-09 1994-08-23 Toagosei Chem Ind Co Ltd Vasculatization inhibitor
WO1994025020A1 (en) * 1993-04-28 1994-11-10 Pharmacia Ab Method and means for inhibiting posterior capsule opacification
US5421818A (en) * 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
WO1996041805A1 (en) * 1993-12-08 1996-12-27 Alcon Laboratories, Inc. Dihydro pyridines having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
WO1995015958A1 (en) * 1993-12-08 1995-06-15 Alcon Laboratories, Inc. Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
JPH07215892A (en) * 1994-01-27 1995-08-15 Sumitomo Pharmaceut Co Ltd Medicinal composition for curing spontaneouse deafness
CN1108539A (en) * 1994-03-16 1995-09-20 吴生武 Eyedrops for curing myopia
WO1995034302A2 (en) * 1994-06-16 1995-12-21 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of calcium chelators
WO1996030366A1 (en) * 1995-03-28 1996-10-03 Ferrer Internacional, S.A. Polymorphs a and b of 1-(diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl) propyl]piperazine
WO1996036334A1 (en) * 1995-05-19 1996-11-21 University Of East Anglia Use of calcium intracellular store inactivators and formulations thereof as cell growth inhibitors
WO1996041638A1 (en) * 1995-06-13 1996-12-27 Sanofi Winthrop, Inc. Calpain inhibitors for the treatment of neurodegenerative diseases
CA2188817A1 (en) * 1995-10-25 1997-04-26 Chiho Fukiage Angiogenesis inhibitor
EP0771565A2 (en) * 1995-10-25 1997-05-07 Senju Pharmaceutical Co., Ltd. Angiogenesis inhibitor
WO1997029756A1 (en) * 1996-02-21 1997-08-21 Inspire Pharmaceuticals, Inc. Method of treating otitis media with uridine triphosphates and related compounds
WO1997034586A2 (en) * 1996-03-22 1997-09-25 Cytotherapeutics, Inc. Device and method for treating ophthalmic diseases
WO1998001128A1 (en) * 1996-07-05 1998-01-15 Mendes S.R.L. Use of l-acetylcarnitine, l-isovalerylcarnitine, l-propionylcarnitine for increasing the levels of igf-1
WO1998018485A1 (en) * 1996-10-31 1998-05-07 Alcon Laboratories, Inc. The use of calpain inhibitors to treat ocular neural pathology
EP0848952A1 (en) * 1996-12-03 1998-06-24 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of lower alkanoyl l-carnitines to produce a medicament suitable for the therapeutic treatment of retinopathies

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Also Published As

Publication number Publication date
WO1998050065A2 (en) 1998-11-12
AU7641798A (en) 1998-11-27
EP0980256A2 (en) 2000-02-23
CA2288631A1 (en) 1998-11-12
DE19718826A1 (en) 1998-11-12

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