UY27894A1 - Derivados de cinamida. - Google Patents

Derivados de cinamida.

Info

Publication number
UY27894A1
UY27894A1 UY27894A UY27894A UY27894A1 UY 27894 A1 UY27894 A1 UY 27894A1 UY 27894 A UY27894 A UY 27894A UY 27894 A UY27894 A UY 27894A UY 27894 A1 UY27894 A1 UY 27894A1
Authority
UY
Uruguay
Prior art keywords
derivatives
cinamide
phenyl
propinamide
propionamido
Prior art date
Application number
UY27894A
Other languages
English (en)
Inventor
Andrew Wilam Thomas
Rosa Maria Rodriguez
Synese Jolidon
Wolfang Wostl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY27894A1 publication Critical patent/UY27894A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

3-Fenil-propionamido, 3-fenil-acrilamido y derivados de 3-fenil-propinamido, procesos para su preparación, composiciones que los contienen y el uso de tales derivados como inhibidores de MAO-B
UY27894A 2002-07-15 2003-07-14 Derivados de cinamida. UY27894A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02015583 2002-07-15

Publications (1)

Publication Number Publication Date
UY27894A1 true UY27894A1 (es) 2003-12-31

Family

ID=30011071

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27894A UY27894A1 (es) 2002-07-15 2003-07-14 Derivados de cinamida.

Country Status (20)

Country Link
US (1) US6900354B2 (es)
EP (1) EP1523469B1 (es)
JP (1) JP4108679B2 (es)
KR (1) KR20050029206A (es)
CN (1) CN1305838C (es)
AR (1) AR040489A1 (es)
AT (1) ATE410407T1 (es)
AU (1) AU2003281030B2 (es)
BR (1) BR0312658A (es)
CA (1) CA2493372A1 (es)
DE (1) DE60323981D1 (es)
ES (1) ES2314219T3 (es)
MX (1) MXPA05000583A (es)
PA (1) PA8577201A1 (es)
PE (1) PE20040667A1 (es)
PL (1) PL373390A1 (es)
RU (1) RU2318802C2 (es)
TW (1) TW200404760A (es)
UY (1) UY27894A1 (es)
WO (1) WO2004007429A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1588704A1 (en) * 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
NZ551144A (en) 2004-05-26 2009-12-24 Eisai R&D Man Co Ltd Cinnamide compound
CA2580119A1 (en) * 2004-10-26 2006-05-04 Eisai R & D Management Co., Ltd. Amorphous object of cinnamide compound
CN101128189A (zh) 2005-02-25 2008-02-20 弗·哈夫曼-拉罗切有限公司 药物物质分散性改善的片剂
ATE540675T1 (de) * 2005-04-01 2012-01-15 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
US8138209B2 (en) * 2005-07-13 2012-03-20 Jenrin Discovery, Inc. Substituted picolinamides as MAO-B inhibitors useful for treating obesity
PL209602B1 (pl) 2005-10-20 2011-09-30 Inst Chemii Bioorg Pan Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego
WO2007058305A1 (ja) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. シンナミド誘導体の製造方法
EP1953151A4 (en) * 2005-11-18 2010-06-02 Eisai R&D Man Co Ltd SALTS FROM A CYNNAMIDE COMPOUND OR SOLVATE THEREOF
CN101312965B (zh) * 2005-11-24 2011-07-20 卫材R&D管理有限公司 吗啉型肉桂酰胺化合物
TWI370130B (en) * 2005-11-24 2012-08-11 Eisai R&D Man Co Ltd Two cyclic cinnamide compound
CA2629745A1 (en) * 2005-11-24 2007-05-31 Eisai R & D Management Co., Ltd. Morpholine type cinnamide compound
TWI378091B (en) * 2006-03-09 2012-12-01 Eisai R&D Man Co Ltd Multi-cyclic cinnamide derivatives
AR062095A1 (es) * 2006-07-28 2008-10-15 Eisai R&D Man Co Ltd Profarmaco de compuesto cinamida
CL2008000582A1 (es) * 2007-02-28 2008-06-27 Eisai R&D Man Co Ltd Compuestos ciclicos derivados de oximorfolina condensados; farmacos que comprenden a dichos compuestos; y su uso para tratar enfermedad de alzheimer, demencia senil, sindrome de down o amiloidosis.
US20080306272A1 (en) * 2007-05-16 2008-12-11 Eisai R&D Management Co., Ltd. One-pot methods for preparing cinnamide derivatives
US7986144B2 (en) * 2007-07-26 2011-07-26 Schlumberger Technology Corporation Sensor and insulation layer structure for well logging instruments
US7935815B2 (en) * 2007-08-31 2011-05-03 Eisai R&D Management Co., Ltd. Imidazoyl pyridine compounds and salts thereof
ES2529648T3 (es) 2007-08-31 2015-02-24 Eisai R&D Management Co., Ltd. Compuesto policíclico
MX2010007969A (es) * 2008-01-28 2010-08-04 Eisai R&D Man Co Ltd Compuestos cristalinos de cinamida o sales de los mismos.
NL2005655A (en) 2009-12-09 2011-06-14 Asml Netherlands Bv A lithographic apparatus and a device manufacturing method.
CN104030941B (zh) * 2014-06-23 2016-04-27 常州大学 一种3-（4-羟基苯基）丙酰胺的合成方法
CN107011313B (zh) * 2016-01-27 2021-11-30 天士力医药集团股份有限公司 取代桂皮酰胺衍生物在制备抗焦虑药物中的应用
KR20200108015A (ko) 2018-01-10 2020-09-16 브라이트씨드, 인크. 대사를 조절하기 위한 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645019A1 (es) * 1989-03-30 1990-10-05 Fournier Innovation Synergie
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
JP3258027B2 (ja) 1996-03-15 2002-02-18 サマーセット・ファーマシューティカルズ・インコーポレイテッド セレジリン投与による末梢ニューロパシーの予防および治療方法
AU1359801A (en) 1999-11-05 2001-06-06 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
BR0312658A (pt) 2005-04-26
RU2005104104A (ru) 2005-10-10
JP4108679B2 (ja) 2008-06-25
PA8577201A1 (es) 2004-02-07
PE20040667A1 (es) 2004-09-25
AR040489A1 (es) 2005-04-06
CN1305838C (zh) 2007-03-21
ES2314219T3 (es) 2009-03-16
AU2003281030B2 (en) 2009-05-28
MXPA05000583A (es) 2005-04-19
TW200404760A (en) 2004-04-01
WO2004007429A1 (en) 2004-01-22
US6900354B2 (en) 2005-05-31
JP2005533092A (ja) 2005-11-04
ATE410407T1 (de) 2008-10-15
US20040034096A1 (en) 2004-02-19
RU2318802C2 (ru) 2008-03-10
PL373390A1 (en) 2005-08-22
AU2003281030A1 (en) 2004-02-02
CA2493372A1 (en) 2004-01-22
DE60323981D1 (de) 2008-11-20
EP1523469B1 (en) 2008-10-08
CN1665774A (zh) 2005-09-07
EP1523469A1 (en) 2005-04-20
KR20050029206A (ko) 2005-03-24

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Legal Events

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Effective date: 20150427