US3563415A - Multidrop adapter - Google Patents

Multidrop adapter Download PDF

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US3563415A
US3563415A US3563415DA US3563415A US 3563415 A US3563415 A US 3563415A US 3563415D A US3563415D A US 3563415DA US 3563415 A US3563415 A US 3563415A
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tubular member
piston
set forth
resilient means
liquid
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Robert W Ogle
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MULTI DROP ADAPTER CORP
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MULTI DROP ADAPTER CORP
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2041—Separating means having removable plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2044—Separating means having slits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing

Definitions

  • the eyedropper with its squeezable rubber bulb affixed to a glass tubing dispenser is a familiar occupant of nearly every medicine cabinet. Nevertheless, when it is desired for example, to give a vaccination by applying a drop of vaccine over an opened portion of the skin of a patient it is still common practice to resort to a syringe or other costly or complicated device for dispensing the single drop of vaccine required. More particularly, the problem becomes compounded when the liquid to be dispensed is one which must be made up just before it is dispensed, as for example, where a powder is mixed with a liquid just before application or where two liquids which are not compatible over any extended period of time are to be mixed just prior to application.
  • FIG. I is a sectional view of a preferred embodiment of the present invention.
  • FIG. 2 is a view similar to FIG. 1 showing the plug after displacement
  • FIG. 3 is a view similar to FIGS. 1 and 2 after a complete depressing of the cylinder and the formation of a drop of liquid about to be released;
  • FIG. 4 is a vertical section of the device illustrated in FIG. 1 and taken along the line 4-4;
  • FIG. 5 is a perspective view of a preferred form of resilient means utilized in the present invention.
  • FIG. 6 is a vertical section of another embodiment of the invention.
  • FIG. 7 is a vertical section of a further embodiment of the invention.
  • FIG. 8 is a vertical section of the device shown in FIG. 7 in a fully depressed condition of the cylinder.
  • a multidrop adapter in the preferred embodiment of which there is utilized a device 10 which is termed herein a cylinder because it receives a plug 11 and a piston 12 but which has an enlarged, hollow head 13 as illustrated.
  • the plug 11 normally fits in the cylinder 10 as indicated in FIG. I but is displaced into the head 13 prior to the dispensing of a drop of liquid as hereinafter described.
  • Head I3 is normally partially filled with a dry substance or powder 14 but the number 14 can be taken to illustrate a liquid other than the liquid 15 which fills the space between the piston I2 and the plug 11.
  • the remaining parts constituting the preferred embodiment are the applicator l6 and the compression pad 17.
  • the applicator I6 is in the form of a cylinder having a flange 18 and an annular skirt I9 the interior of which cylinder receives in sliding fit the exterior of the cylinder 10.
  • Piston 12 is generally in the form of a solid flexible member of rubber or rubberlike material having a longitudinal central passage or bore 20.
  • the tapered underside 25 of end 22 is cemented or glued to inner cylinder 26 by joining material 27 so that piston 12 is effectively held in place during operation of the device.
  • the compression pad 17 is preferably made of rubber and has the form of a ring with three downturned legs 28 which in use rest upon the bottom of applicator 16 in the annular space between the outer wall of applicator I6 and cylinder 26.
  • the device may be provided with a cap 29 which seals on both skirt l9 and nose 21 to maintain sterility. The cap is removed prior to operation of the device.
  • the operation of the above-described device is as follows: Assuming the device illustrated to be filled with a liquid 15 between the plug 11 and the piston 12 and a powder 14in the head 13. The device is held in an upright position with the head 13 low and the nose 21 high. In this position a collapsing of the device by pressing the cylinder 10 into the applicator l6 and over the piston I2 will cause the plug 11 to be blown into the head 13 as indicated in FIG. 2. In this condition the liquid 15 may mix with the powder 14 (or two liquids may mix). Thereafter, the device is inverted, the nose 21 is pointed at the spot where a drop of liquid 30 is desired and the device is further collapsed to the condition shown in FIG.
  • FIG. 6 there is shown an embodiment of the invention wherein the cylinder 31 differs from the cylinder 10 by not having an enlarged head 13 and by having a closed end 32 instead of a plug 11. Obviously, this device merely dispenses a drop of liquid and does not perform any mixing function. All of the remaining parts are identical with those of the previous embodiment.
  • FIGS. 7 and 8 there is shown a further embodiment of the invention wherein a cylinder 33 has a plug 34, a piston 35 and an enlarged head 36 generally comparable to the correlative numbers 10--I3 of the first embodiment.
  • An applicator 37 similar to the applicator 116 has a flange 38 and a reduced hub 39.
  • the applicator 37 includes an integral upstanding cylindrical portion 40 preferably formed integrally with the remainder of the applicator 37 and spaced inwardly from the sidewall of the applicator to leave an annular space 41.
  • a coil spring 42 surrounds the member 40 in the annular space 41 and has its upper end engaging the flange 43 of a member 44.
  • Member 44 is preferably formed of plastic and is a cylindrical sleeve adapted to fit over the upstanding member 7 40 and have its flange 43 also engaged by the end of the cylinder 33 as clearly shown in FIGS. 7 and 8.
  • the upstanding member 40 may be internally threaded as at 49 to receive the external threads 45 of a rubber piston 35 threaded therein as indicated.
  • a tube 46 is cemented in the bore 47 of the hub 39 and extends upwardly within the member 40 and into the bore 48 of piston 35 as shown.
  • a multidrop dispenser comprising:
  • first tubular member having an open end and a closed end
  • a second tubular member having an open end and a partially closed end, said first tubular member being telescopically slidable in said second tubular member;
  • resilient means having extended and collapsed positions carried by said second tubular member and adapted to engage said first tubular member and biasing said first tubular member towards extended rather than collapsed position of said resilient means.
  • a multidrop dispenser as set forth in claim 1 in which said first tubular member is provided with an enlarged head and a stopper adapted to be forced into said enlarged head upon partial telescopic movement of said first tubular member into said second tubular member.
  • a multidrop dispenser as set forth in claim 1 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
  • a multidrop dispenser as set forth in claim 2 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
  • a multidrop dispenser as set forth in claim 1 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
  • a multidrop dispenser as set forth in claim 2 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
  • said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
  • a multidrop dispenser as set forth in claim 2 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
  • a multidrop dispenser as set forth in claim 4 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Coating Apparatus (AREA)

Abstract

A multidrop adapter or dispenser in which a tubular member which may have an enlarged head for containing a powder or substance to be mixed with a liquid in the remainder of the tubular member is telescopically received in a second tubular member which seals one end of a piston which extends into the first tubular member and has a bore which extends out of said second tubular member to expel a drop of liquid when said first tubular member is telescopically moved into said second tubular member and over said piston; and resilient means biasing said first tubular member out of said second tubular member. A plug in said first tubular member is dispelled into said enlarged head upon movement of said first tubular member over said piston when said enlarged head is employed in the invention.

Description

United States Patent Primary Examiner-Samuel F. Coleman Assistant Examiner-Norman L. Stack, Jr. Attorney-Finkelstein and Mueth ABSTRACT: A multidrop adapter or dispenser in which a tubular member which may have an enlarged head for containing a powder or substance to be mixed with a liquid in the remainder of the tubular member is telescopically received in a second tubular member which seals one end of a piston which extends into the first tubular member and has a bore which extends out of said second tubular member to expel a drop of liquid when said first tubular :member is telescopically moved into said second tubular member and over said piston; and resilient means biasing said first tubular member out of said second tubular member. A plug in said first tubular member is dispelled into said enlarged head upon movement of said first tubular member over said piston when said enlarged head is employed in the invention.
PATENTED m1 6l97| SHEET 1 BF 2 INVENTOR 605667- W. 0646 a ax Arrow/6V5 MUL'IIDROP ADAPTER BACKGROUND OF INVENTION Devices for dispensing repeated drops of medicine or other liquids for a variety of purposes are of great antiquity hence the man skilled in the art hasa wealth of historic development from which to draw. Perhaps the simplest such device constitutes a mere short length of tubing, such as a straw, which can be filled or partially filled with water or other liquid and drops dispensed by alternately placing and removing a finger from the upper end of such an inverted straw. The eyedropper with its squeezable rubber bulb affixed to a glass tubing dispenser is a familiar occupant of nearly every medicine cabinet. Nevertheless, when it is desired for example, to give a vaccination by applying a drop of vaccine over an opened portion of the skin of a patient it is still common practice to resort to a syringe or other costly or complicated device for dispensing the single drop of vaccine required. More particularly, the problem becomes compounded when the liquid to be dispensed is one which must be made up just before it is dispensed, as for example, where a powder is mixed with a liquid just before application or where two liquids which are not compatible over any extended period of time are to be mixed just prior to application.
Accordingly, it is one object of the present invention to provide a multidrop adapter which retains the traditional simplicity of such devices and yet is capable of dispensing a plurality of carefully measured single drops of liquid,which may be in one of the embodiments of this invention a liquid which has just been constituted, in situ, by mixing together a powder and a liquid or two liquids just prior to their use.
These and other objects and advantages of this invention will be apparent from the more detailed description which follows.
DESCRIPTION OF PREFERRED EMBODIMENTS Turning to the drawings:
FIG. I is a sectional view of a preferred embodiment of the present invention;
FIG. 2 is a view similar to FIG. 1 showing the plug after displacement;
FIG. 3 is a view similar to FIGS. 1 and 2 after a complete depressing of the cylinder and the formation of a drop of liquid about to be released; I
FIG. 4 is a vertical section of the device illustrated in FIG. 1 and taken along the line 4-4;
FIG. 5 is a perspective view of a preferred form of resilient means utilized in the present invention;
FIG. 6 is a vertical section of another embodiment of the invention;
FIG. 7 is a vertical section of a further embodiment of the invention; and
FIG. 8 is a vertical section of the device shown in FIG. 7 in a fully depressed condition of the cylinder.
Referring now more particularly to the drawings, there is illustrated a multidrop adapter in the preferred embodiment of which there is utilized a device 10 which is termed herein a cylinder because it receives a plug 11 and a piston 12 but which has an enlarged, hollow head 13 as illustrated. The plug 11 normally fits in the cylinder 10 as indicated in FIG. I but is displaced into the head 13 prior to the dispensing of a drop of liquid as hereinafter described.
Head I3 is normally partially filled with a dry substance or powder 14 but the number 14 can be taken to illustrate a liquid other than the liquid 15 which fills the space between the piston I2 and the plug 11.
The remaining parts constituting the preferred embodiment are the applicator l6 and the compression pad 17.
The applicator I6 is in the form of a cylinder having a flange 18 and an annular skirt I9 the interior of which cylinder receives in sliding fit the exterior of the cylinder 10.
Piston 12 is generally in the form of a solid flexible member of rubber or rubberlike material having a longitudinal central passage or bore 20. A nose 21 of reduced cross section, and an enlarged upper end 22 having a pair ofspaced sealing rings 23 and 24 formed thereon and adapted to sealingly engage the exterior of the cylinder 10. The tapered underside 25 of end 22 is cemented or glued to inner cylinder 26 by joining material 27 so that piston 12 is effectively held in place during operation of the device.
The compression pad 17 is preferably made of rubber and has the form of a ring with three downturned legs 28 which in use rest upon the bottom of applicator 16 in the annular space between the outer wall of applicator I6 and cylinder 26.
For storage, the device may be provided with a cap 29 which seals on both skirt l9 and nose 21 to maintain sterility. The cap is removed prior to operation of the device.
The operation of the above-described device is as follows: Assuming the device illustrated to be filled with a liquid 15 between the plug 11 and the piston 12 and a powder 14in the head 13. The device is held in an upright position with the head 13 low and the nose 21 high. In this position a collapsing of the device by pressing the cylinder 10 into the applicator l6 and over the piston I2 will cause the plug 11 to be blown into the head 13 as indicated in FIG. 2. In this condition the liquid 15 may mix with the powder 14 (or two liquids may mix). Thereafter, the device is inverted, the nose 21 is pointed at the spot where a drop of liquid 30 is desired and the device is further collapsed to the condition shown in FIG. 3 in which the end of cylinder 10 contacts the ring portion of pad 17, collapses the legs 28 thereof and forces a drop or bead of liquid 30 to fall from the nose 21. Thereafter, the head 13 may be released and the device will return to its original expanded condition, with the plug 11, however, still in head 13, under the force of the resilience of the legs 28 of pad 17. The return of the device to the expanded position draws air into the head 13 through bore 20 to permit the forming of a succeeding drop.
Referring now more particularly to FIG. 6, there is shown an embodiment of the invention wherein the cylinder 31 differs from the cylinder 10 by not having an enlarged head 13 and by having a closed end 32 instead of a plug 11. Obviously, this device merely dispenses a drop of liquid and does not perform any mixing function. All of the remaining parts are identical with those of the previous embodiment.
Turning now to FIGS. 7 and 8, there is shown a further embodiment of the invention wherein a cylinder 33 has a plug 34, a piston 35 and an enlarged head 36 generally comparable to the correlative numbers 10--I3 of the first embodiment. An applicator 37 similar to the applicator 116 has a flange 38 and a reduced hub 39. The applicator 37 includes an integral upstanding cylindrical portion 40 preferably formed integrally with the remainder of the applicator 37 and spaced inwardly from the sidewall of the applicator to leave an annular space 41. A coil spring 42 surrounds the member 40 in the annular space 41 and has its upper end engaging the flange 43 of a member 44. Member 44 is preferably formed of plastic and is a cylindrical sleeve adapted to fit over the upstanding member 7 40 and have its flange 43 also engaged by the end of the cylinder 33 as clearly shown in FIGS. 7 and 8. The upstanding member 40 may be internally threaded as at 49 to receive the external threads 45 of a rubber piston 35 threaded therein as indicated. A tube 46 is cemented in the bore 47 of the hub 39 and extends upwardly within the member 40 and into the bore 48 of piston 35 as shown.
The operation of the device shown in FIGS. 7 and 8 is identical with that of FIGS. 1-6 with the coil spring 42 I claim:
1. A multidrop dispenser comprising:
a first tubular member having an open end and a closed end;
a second tubular member having an open end and a partially closed end, said first tubular member being telescopically slidable in said second tubular member;
a piston in said first tubular member and having a portion extending into and through the partially closed end of said second tubular member;
a central bore in said piston; and
resilient means having extended and collapsed positions carried by said second tubular member and adapted to engage said first tubular member and biasing said first tubular member towards extended rather than collapsed position of said resilient means.
2. A multidrop dispenser as set forth in claim 1 in which said first tubular member is provided with an enlarged head and a stopper adapted to be forced into said enlarged head upon partial telescopic movement of said first tubular member into said second tubular member.
3. A multidrop dispenser as set forth in claim 1 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
4. A multidrop dispenser as set forth in claim 2 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
5. A multidrop dispenser as set forth in claim 1 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
6. A multidrop dispenser as set forth in claim 2 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
7. A multidrop dispenser as set forth in claim 3 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
8. A multidrop dispenser as set forth in claim 1 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
9. A multidrop dispenser as set forth in claim 2 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
10. A multidrop dispenser as set forth in claim 4 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.

Claims (10)

1. A multidrop dispenser comprising: a first tubular member having an open end and a closed end; a second tubular member having an open end and a partially closed end, said first tubular member being telescopically slidable in said second tubular member; a piston in said first tubular member and having a portion extending into and through the partially closed end of said second tubular member; a central bore in said piston; and resilient means having extended and collapsed positions carried by said second tubular member and adapted to engage said first tubular member and biasing said first tubular member towards extended rather than collapsed position of said resilient means.
2. A multidrop dispenser as set forth in claim 1 in which said first tubular member is provided with an enlarged head and a stopper adapted to be forced into said enlarged head upon partial telescopic movement of said first tubular member into said second tubular member.
3. A multidrop dispenser as set forth in claim 1 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
4. A multidrop dispenser as set forth in claim 2 in which said piston terminates in a nose upon which a bead, a drop, of liquid is formed upon expulsion of such liquid from said first tubular member through said bore by telescopic movement of said first tubular member into said second tubular member and over said piston.
5. A multidrop dispenser as set forth in claim 1 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
6. A multidrop dispenser as set forth in claim 2 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
7. A multidrop dispenser as set forth in claim 3 in which said resilient means comprises a rubberlike ring member adapted to be compressed upon movement of said first tubular member into said second tubular member.
8. A multidrop dispenser as set forth in claim 1 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end anD the inner end of said first tubular member at the other end thereof.
9. A multidrop dispenser as set forth in claim 2 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
10. A multidrop dispenser as set forth in claim 4 in which said resilient means comprises a coil spring seated in said second tubular member and adapted to engage the partially closed end thereof at one end and the inner end of said first tubular member at the other end thereof.
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US3788528A (en) * 1971-08-23 1974-01-29 Ims Ltd Mini dropper
US3968872A (en) * 1973-08-03 1976-07-13 Sigma-Tau Device, provided with a puncher and a dripper, for the hermetic sealing of containers
US4142656A (en) * 1976-12-17 1979-03-06 Eastman Kodak Company Drop former utilizing gas pressure
US4657534A (en) * 1985-11-04 1987-04-14 Alcon Laboratories, Inc. Dual compartment, disposable, mixing and dispensing container
US4741737A (en) * 1982-12-20 1988-05-03 Medicorp Holding S.A. Prefilled ampoule-syringe
US4776704A (en) * 1986-12-15 1988-10-11 Dentsply Research & Development Corp. Mixing and dispensing syringe
WO1990007318A1 (en) * 1988-12-27 1990-07-12 Medicorp Holding S.A. Storage and transfer bottle designed for storing a component of a medicamental substance
WO1990007319A1 (en) * 1988-12-27 1990-07-12 Medicorp Holding S.A. Storage and transfer bottle designed for storing two components of a medicamental substance
US4941876A (en) * 1986-04-10 1990-07-17 Medicorp Holding S.A. Device for conditioning liquids or liquid and solid substances
US4979941A (en) * 1989-12-05 1990-12-25 International Medication Systems, Limited Device suitable for mixing medication
US5114411A (en) * 1990-11-19 1992-05-19 Habley Medical Technology Corporation Multi-chamber vial
US5169388A (en) * 1990-06-07 1992-12-08 Gensia Pharmaceuticals, Inc. Pressure-activated medication dispenser
US5176634A (en) * 1990-08-02 1993-01-05 Mcgaw, Inc. Flexible multiple compartment drug container
US5267986A (en) * 1992-04-06 1993-12-07 Self-Instill & Co., Inc. Cartridge for applying medicament to an eye from a dispenser
US5330048A (en) * 1993-07-09 1994-07-19 Habley Medical Technology Corporation Controlled access mixing vial
US5401259A (en) * 1992-04-06 1995-03-28 Py Daniel C Cartridge for applying medicament to an eye
US5478324A (en) * 1993-02-19 1995-12-26 Medicorp Holding S.A. Prefilled syringe for storing and for transfer of liquid and sterile medicinal substances
US5526853A (en) * 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
US5613957A (en) * 1991-12-02 1997-03-25 Daniel Py Apparatus for applying medicament to an eye
US5641010A (en) * 1994-07-14 1997-06-24 International Medication Systems, Limited Mixing and dispensing apparatus
US6213597B1 (en) * 2000-02-29 2001-04-10 Win-Yin Liu Apparatus for ink cartridge of a jet printer
WO2001051110A1 (en) * 2000-01-14 2001-07-19 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US20010013554A1 (en) * 1999-09-09 2001-08-16 Scott Borland Aperture plate and methods for its construction and use
US20030150445A1 (en) * 2001-11-01 2003-08-14 Aerogen, Inc. Apparatus and methods for delivery of medicament to a respiratory system
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