UA96745C2 - PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS - Google Patents

PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS

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Publication number
UA96745C2
UA96745C2 UAA200808079A UAA200808079A UA96745C2 UA 96745 C2 UA96745 C2 UA 96745C2 UA A200808079 A UAA200808079 A UA A200808079A UA A200808079 A UAA200808079 A UA A200808079A UA 96745 C2 UA96745 C2 UA 96745C2
Authority
UA
Ukraine
Prior art keywords
pyrazo
pyrimido
pyrido
pyrimidine derivatives
mtor inhibitors
Prior art date
Application number
UAA200808079A
Other languages
English (en)
Ukrainian (uk)
Inventor
Марк Джеффри Хаммерсон
Сильви Гомез
Кейт Аллан Минер
Грейм Камерон Марри Смит
Карине Малагу
Хедер Мери Эллен Дагган
Сяо-Лин Фань Кокрофт
Гезине Йоханна Германн
Original Assignee
Кудос Фармасьютикалз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кудос Фармасьютикалз Лимитед filed Critical Кудос Фармасьютикалз Лимитед
Publication of UA96745C2 publication Critical patent/UA96745C2/ru

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Раскрыты соединения формулы I:, (I)которые пригодны для лечения злокачественного новообразования.
UAA200808079A 2005-11-22 2006-11-20 PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS UA96745C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73890205P 2005-11-22 2005-11-22

Publications (1)

Publication Number Publication Date
UA96745C2 true UA96745C2 (en) 2011-12-12

Family

ID=40332775

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200808079A UA96745C2 (en) 2005-11-22 2006-11-20 PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS

Country Status (3)

Country Link
CN (1) CN101360746B (ru)
UA (1) UA96745C2 (ru)
ZA (1) ZA200804104B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101914483B (zh) * 2010-09-02 2013-07-31 福建新大陆生物技术股份有限公司 一种液基薄层细胞保存处理液及其用途
CN102887895B (zh) * 2011-07-22 2016-08-24 山东轩竹医药科技有限公司 吡啶并嘧啶类mTOR抑制剂
CN103588792B (zh) * 2013-03-04 2016-03-23 中国科学院上海药物研究所 吡啶并嘧啶或嘧啶并嘧啶类化合物、其制备方法、药物组合物及其用途
CN105669731B (zh) * 2016-01-10 2017-06-30 沧州普瑞东方科技有限公司 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法
US11377444B2 (en) 2017-11-06 2022-07-05 Medshine Discovery Inc. Pyridopyrimidine compounds acting as mTORC 1/2 dual inhibitors
KR20240134949A (ko) * 2022-01-17 2024-09-10 수조우 푸허 바이오파마 컴퍼니 리미티드 Egfr 억제제 역할을 하는 2-피페리딜 또는 2-피라졸릴 치환된 피리미딘 화합물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2407593C (en) * 2000-04-27 2011-01-11 Yamanouchi Pharmaceutical Co. Ltd. Fused heteroaryl derivatives
ATE330956T1 (de) * 2001-04-13 2006-07-15 Pfizer Prod Inc Bizyklisch substituierte 4- aminopyridopyrimidinderivate
US20040156869A1 (en) * 2002-12-13 2004-08-12 Neurogen Corporation 2-substituted quinazolin-4-ylamine analogues

Also Published As

Publication number Publication date
CN101360746A (zh) 2009-02-04
CN101360746B (zh) 2013-12-11
ZA200804104B (en) 2009-11-25

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