TR201901062T4 - Modifiye meningokokal fhbp polipeptidleri. - Google Patents

Modifiye meningokokal fhbp polipeptidleri. Download PDF

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Publication number
TR201901062T4
TR201901062T4 TR2019/01062T TR201901062T TR201901062T4 TR 201901062 T4 TR201901062 T4 TR 201901062T4 TR 2019/01062 T TR2019/01062 T TR 2019/01062T TR 201901062 T TR201901062 T TR 201901062T TR 201901062 T4 TR201901062 T4 TR 201901062T4
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TR
Turkey
Prior art keywords
meningococcal fhbp
fhbp polypeptides
modified meningococcal
modified
polypeptides
Prior art date
Application number
TR2019/01062T
Other languages
English (en)
Inventor
Bottomley Matthew
Masignani Vega
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of TR201901062T4 publication Critical patent/TR201901062T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Buluş sahipleri, meningokokal fHbp varyant 2 ve varyant 3 içinde, bu varyantların özelliklerini geliştirmek maksadıyla modifiye edilebilecek olan artıklar belirleyip tanımlamışlardır.
TR2019/01062T 2014-07-17 2015-07-16 Modifiye meningokokal fhbp polipeptidleri. TR201901062T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14177564 2014-07-17

Publications (1)

Publication Number Publication Date
TR201901062T4 true TR201901062T4 (tr) 2019-02-21

Family

ID=51178812

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/01062T TR201901062T4 (tr) 2014-07-17 2015-07-16 Modifiye meningokokal fhbp polipeptidleri.

Country Status (18)

Country Link
US (3) US11066450B2 (tr)
EP (1) EP3169357B1 (tr)
JP (1) JP2017522320A (tr)
KR (1) KR20170023191A (tr)
CN (1) CN106795208A (tr)
AR (1) AR102324A1 (tr)
AU (1) AU2015289192A1 (tr)
BE (1) BE1022641B1 (tr)
BR (1) BR112017000521A2 (tr)
CA (1) CA2954745A1 (tr)
EA (1) EA201692552A1 (tr)
ES (1) ES2722773T3 (tr)
IL (1) IL249822A0 (tr)
MX (1) MX2017000776A (tr)
SG (1) SG11201610945PA (tr)
TR (1) TR201901062T4 (tr)
WO (1) WO2016008960A1 (tr)
ZA (1) ZA201700170B (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2910199T3 (es) 2010-03-30 2022-05-11 Childrens Hospital & Res Center At Oakland Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas
WO2015128480A1 (en) * 2014-02-28 2015-09-03 Novartis Ag Modified meningococcal fhbp polypeptides
IL249823B (en) 2014-07-17 2022-07-01 Glaxosmithkline Biologicals Sa Meningococcus vaccines
CA2954745A1 (en) 2014-07-17 2016-01-21 Glaxosmithkline Biologicals S.A. Modified meningococcal fhbp polypeptides
KR20230155595A (ko) 2014-07-23 2023-11-10 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 인자 h 결합 단백질 변이체 및 이의 사용 방법
CN110248681A (zh) * 2016-11-25 2019-09-17 葛兰素史密丝克莱恩生物有限公司 nOMV-抗原缀合物及其用途
EP3607967A1 (en) * 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
IT201900003947A1 (it) * 2019-03-19 2020-09-19 Mt Ortho S R L Granulo in materiale metallico biocompatibile per vertebroplastica.
CN114929660A (zh) 2019-12-19 2022-08-19 陶氏技术投资有限责任公司 用于制备异戊二烯和包含至少六个碳原子的单烯烃的方法
EP4294432A1 (en) 2021-02-19 2023-12-27 Sanofi Pasteur, Inc. Meningococcal b recombinant vaccine
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods
GB202208093D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
GB202208089D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747137B1 (en) 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
US6551795B1 (en) 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
PT1248647E (pt) 2000-01-17 2010-11-18 Novartis Vaccines & Diagnostics Srl Vacina de vesícula da membrana externa (omv) compreendendo proteínas de membrana externa de n. meningitidis do serogrupo b
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0419408D0 (en) 2004-09-01 2004-10-06 Chiron Srl 741 chimeric polypeptides
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
US20130022633A1 (en) * 2009-10-27 2013-01-24 University Of Florence MENINGOCOCCAL fHBP POLYPEPTIDES
CN102869378A (zh) 2010-03-10 2013-01-09 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
ES2910199T3 (es) 2010-03-30 2022-05-11 Childrens Hospital & Res Center At Oakland Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas
GB201120634D0 (en) 2011-11-30 2012-01-11 Univ Sheffield Adjuvant polypeptide
CN104602704B (zh) 2012-06-14 2019-08-06 诺华股份有限公司 针对血清组x脑膜炎球菌的疫苗
GB201215005D0 (en) 2012-08-23 2012-10-10 Isis Innovation Stabilised meningitis vaccine
WO2015128480A1 (en) 2014-02-28 2015-09-03 Novartis Ag Modified meningococcal fhbp polypeptides
CA2954745A1 (en) * 2014-07-17 2016-01-21 Glaxosmithkline Biologicals S.A. Modified meningococcal fhbp polypeptides
IL249823B (en) 2014-07-17 2022-07-01 Glaxosmithkline Biologicals Sa Meningococcus vaccines

Also Published As

Publication number Publication date
AU2015289192A1 (en) 2017-02-02
EA201692552A1 (ru) 2017-06-30
CN106795208A (zh) 2017-05-31
BE1022641B1 (fr) 2016-06-23
EP3169357B1 (en) 2018-11-07
WO2016008960A1 (en) 2016-01-21
US20220002355A1 (en) 2022-01-06
BE1022641A1 (fr) 2016-06-23
EP3169357A1 (en) 2017-05-24
US20170226161A1 (en) 2017-08-10
ZA201700170B (en) 2019-06-26
US11066450B2 (en) 2021-07-20
BR112017000521A2 (pt) 2017-11-21
KR20170023191A (ko) 2017-03-02
IL249822A0 (en) 2017-03-30
US20240327470A1 (en) 2024-10-03
ES2722773T3 (es) 2019-08-16
AR102324A1 (es) 2017-02-22
MX2017000776A (es) 2017-05-04
US11939357B2 (en) 2024-03-26
SG11201610945PA (en) 2017-01-27
CA2954745A1 (en) 2016-01-21
JP2017522320A (ja) 2017-08-10

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