SK283263B6 - Fluóralkoxysubstituované benzamidy, spôsob ich výroby a ich použitie ako inhibítorov fosfodiesterázy cyklických nukleotidov - Google Patents

Fluóralkoxysubstituované benzamidy, spôsob ich výroby a ich použitie ako inhibítorov fosfodiesterázy cyklických nukleotidov Download PDF

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Publication number
SK283263B6
SK283263B6 SK1617-95A SK161795A SK283263B6 SK 283263 B6 SK283263 B6 SK 283263B6 SK 161795 A SK161795 A SK 161795A SK 283263 B6 SK283263 B6 SK 283263B6
Authority
SK
Slovakia
Prior art keywords
alkyl
pyridyl
halogen
alkoxy
hydrogen
Prior art date
Application number
SK1617-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK161795A3 (en
Inventor
Hermann Amschler
Dieter Flockerzi
Beate Gutterer
Armin Hatzelmann
Christian Schudt
Rolf Beume
Ulrich Kilian
Horst P. O. Wolf
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4223466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK283263(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of SK161795A3 publication Critical patent/SK161795A3/sk
Publication of SK283263B6 publication Critical patent/SK283263B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
SK1617-95A 1993-07-02 1994-07-02 Fluóralkoxysubstituované benzamidy, spôsob ich výroby a ich použitie ako inhibítorov fosfodiesterázy cyklických nukleotidov SK283263B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH199693 1993-07-02
PCT/EP1994/002169 WO1995001338A1 (de) 1993-07-02 1994-07-02 Fluoralkoxy substituierte benzamide und ihre verwendung als zyklisch-nukleotid phosphodiesterase-inhibitoren

Publications (2)

Publication Number Publication Date
SK161795A3 SK161795A3 (en) 1996-07-03
SK283263B6 true SK283263B6 (sk) 2003-04-01

Family

ID=4223466

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1617-95A SK283263B6 (sk) 1993-07-02 1994-07-02 Fluóralkoxysubstituované benzamidy, spôsob ich výroby a ich použitie ako inhibítorov fosfodiesterázy cyklických nukleotidov

Country Status (28)

Country Link
US (1) US5712298A (zh)
EP (1) EP0706513B1 (zh)
JP (1) JP3093271B2 (zh)
KR (1) KR100331255B1 (zh)
CN (1) CN1046939C (zh)
AT (1) ATE217612T1 (zh)
AU (1) AU687087B2 (zh)
CA (1) CA2165192C (zh)
CY (2) CY2389B1 (zh)
CZ (1) CZ290266B6 (zh)
DE (2) DE59410119D1 (zh)
DK (1) DK0706513T3 (zh)
ES (1) ES2176252T3 (zh)
FI (1) FI112864B (zh)
FR (1) FR10C0052I2 (zh)
HK (1) HK1011690A1 (zh)
HU (1) HU220041B (zh)
LU (1) LU91709I2 (zh)
LV (1) LV13074B (zh)
NO (2) NO305598B1 (zh)
NZ (1) NZ271316A (zh)
PL (1) PL178314B1 (zh)
PT (1) PT706513E (zh)
RU (1) RU2137754C1 (zh)
SG (1) SG143011A1 (zh)
SI (1) SI0706513T1 (zh)
SK (1) SK283263B6 (zh)
WO (1) WO1995001338A1 (zh)

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