SI3589730T1 - Adeno-povezan virus (AAV) clade F vektor in njihova uporaba - Google Patents
Adeno-povezan virus (AAV) clade F vektor in njihova uporabaInfo
- Publication number
- SI3589730T1 SI3589730T1 SI201831066T SI201831066T SI3589730T1 SI 3589730 T1 SI3589730 T1 SI 3589730T1 SI 201831066 T SI201831066 T SI 201831066T SI 201831066 T SI201831066 T SI 201831066T SI 3589730 T1 SI3589730 T1 SI 3589730T1
- Authority
- SI
- Slovenia
- Prior art keywords
- clade
- aav
- adeno
- vector
- associated virus
- Prior art date
Links
- 241000702421 Dependoparvovirus Species 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762464748P | 2017-02-28 | 2017-02-28 | |
| US201762591002P | 2017-11-27 | 2017-11-27 | |
| US201862614002P | 2018-01-05 | 2018-01-05 | |
| EP18711202.4A EP3589730B1 (en) | 2017-02-28 | 2018-02-27 | Adeno-associated virus (aav) clade f vector and uses therefor |
| PCT/US2018/019992 WO2018160582A1 (en) | 2017-02-28 | 2018-02-27 | Adeno-associated virus (aav) clade f vector and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3589730T1 true SI3589730T1 (sl) | 2024-04-30 |
Family
ID=61628475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201831066T SI3589730T1 (sl) | 2017-02-28 | 2018-02-27 | Adeno-povezan virus (AAV) clade F vektor in njihova uporaba |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US11827906B2 (sl) |
| EP (2) | EP4272765A3 (sl) |
| JP (2) | JP7455579B2 (sl) |
| KR (1) | KR20190132639A (sl) |
| CN (1) | CN110741082B (sl) |
| AU (2) | AU2018227440B2 (sl) |
| BR (1) | BR112019017839A2 (sl) |
| CA (1) | CA3053399A1 (sl) |
| CL (1) | CL2019002474A1 (sl) |
| CO (1) | CO2019009525A2 (sl) |
| DK (1) | DK3589730T5 (sl) |
| ES (1) | ES2971872T3 (sl) |
| FI (1) | FI3589730T3 (sl) |
| HR (1) | HRP20240257T1 (sl) |
| HU (1) | HUE065885T2 (sl) |
| IL (1) | IL268644A (sl) |
| LT (1) | LT3589730T (sl) |
| MD (1) | MD3589730T2 (sl) |
| MX (1) | MX2019010275A (sl) |
| PE (1) | PE20191362A1 (sl) |
| PL (1) | PL3589730T3 (sl) |
| PT (1) | PT3589730T (sl) |
| RS (1) | RS65241B1 (sl) |
| SA (1) | SA519402565B1 (sl) |
| SG (4) | SG10201912969XA (sl) |
| SI (1) | SI3589730T1 (sl) |
| WO (1) | WO2018160582A1 (sl) |
| ZA (1) | ZA201905407B (sl) |
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| ES2455126T3 (es) | 2001-11-13 | 2014-04-14 | The Trustees Of The University Of Pennsylvania | Secuencias Cy.5 de virus adeno-asociados (AAV), vectores que las contienen y uso de las mismas. |
| DK2345731T3 (en) | 2003-09-30 | 2016-01-25 | Univ Pennsylvania | Adeno-associated virus (AAV) groupings, sequences, vectors containing the same and uses thereof |
| DK3356390T3 (da) | 2015-09-28 | 2021-04-12 | Univ North Carolina Chapel Hill | Fremgangsmåder og sammensætninger til virusvektorer, der undgår antistoffer |
| DK3402483T3 (da) * | 2016-01-15 | 2024-01-02 | American Gene Tech Int Inc | Fremgangsmåder og sammensætninger til aktivering af gamma-delta-T-celler |
| SI3589730T1 (sl) | 2017-02-28 | 2024-04-30 | The Trustees Of The University Of Pennsylvania | Adeno-povezan virus (AAV) clade F vektor in njihova uporaba |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| RU2019139555A (ru) | 2017-05-11 | 2021-06-11 | Зе Трастис Оф Зе Юниверсити Оф Пеннсильвания | Генная терапия нейрональных цероидных липофусцинозов |
| SG11202004991SA (en) | 2017-11-30 | 2020-06-29 | Univ Pennsylvania | Gene therapy for mucopolysaccharidosis iiib |
| JP7389744B2 (ja) | 2017-11-30 | 2023-11-30 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | ムコ多糖症ｉｉｉａ型のための遺伝子療法 |
| EP3758724A4 (en) * | 2018-02-27 | 2022-07-06 | The Trustees of The University of Pennsylvania | NOVEL ADENO-ASSOCIATED VIRUS (AAV) VECTORS, AAV VECTORS WITH REDUCED CAPSID DEAMIDATION AND USES THEREOF |
| CN112236443A (zh) * | 2018-02-27 | 2021-01-15 | 宾夕法尼亚州大学信托人 | 新颖腺相关病毒(aav)载体、具有降低的衣壳脱酰胺化的aav载体及其用途 |
| CN112272672A (zh) | 2018-04-03 | 2021-01-26 | 斯特里迪比奥公司 | 抗体逃避性病毒载体 |
| WO2019195444A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
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| US20230040603A1 (en) * | 2018-10-01 | 2023-02-09 | The Trustees Of The University Of Pennsylvania | Compositions useful for treating gm1 gangliosidosis |
| UY38407A (es) | 2018-10-15 | 2020-05-29 | Novartis Ag | Anticuerpos estabilizadores de trem2 |
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| BR112021015817A2 (pt) | 2019-02-22 | 2021-10-13 | The Trustees Of The University Of Pennsylvania | Vírus adeno-associado recombinante para tratamento de neurodegeneração com início na idade adulta associado a grn |
| CA3130055A1 (en) * | 2019-02-26 | 2020-09-03 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of krabbe disease |
| CN113727992A (zh) | 2019-03-21 | 2021-11-30 | 斯特里迪比奥公司 | 重组腺相关病毒载体 |
| CA3133889A1 (en) * | 2019-04-24 | 2020-10-29 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of rett syndrome |
| SG11202111867XA (en) * | 2019-05-03 | 2021-11-29 | Univ Pennsylvania | Compositions useful in treatment of metachromatic leukodystrophy |
| IL292297A (en) | 2019-10-17 | 2022-06-01 | Stridebio Inc | Adeno-associated viral vectors for the treatment of Niemann-Pick type c disease |
| AU2020398904A1 (en) * | 2019-12-10 | 2022-06-30 | Homology Medicines, Inc. | Adeno-associated virus compositions and methods of use thereof |
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| AR123838A1 (es) | 2020-10-18 | 2023-01-18 | Univ Pennsylvania | Vector mejorado de virus adenoasociado (aav) y usos de este |
| JP2023546689A (ja) * | 2020-10-22 | 2023-11-07 | スカウト バイオ， インコーポレイテッド | ベクター送達される治療用タンパク質に対する免疫応答を抑制する方法 |
| WO2022094078A1 (en) | 2020-10-28 | 2022-05-05 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of rett syndrome |
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| US20230390418A1 (en) * | 2020-10-29 | 2023-12-07 | Regenxbio Inc. | Vectorized factor xii antibodies and administration thereof |
| AU2021378075A1 (en) | 2020-11-11 | 2023-06-22 | Borea Therapeutics S.R.L. | Modified viral particles for gene therapy |
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| JP2023551911A (ja) | 2020-12-01 | 2023-12-13 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | アンジェルマン症候群の治療のための組成物及びその使用 |
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| WO2023133584A1 (en) | 2022-01-10 | 2023-07-13 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of metachromatic leukodystrophy |
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